Conservation of cofitness between A4249_RS03825 and A4249_RS07745 in Brevundimonas sp. GW460-12-10-14-LB2

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS03825 MATE family efflux transporter 1.0 A4249_RS07745 glucuronate isomerase 0.59 2
Caulobacter crescentus NA1000 Δfur 0.44 CCNA_02099 Na+ driven multidrug efflux pump 0.62 CCNA_01557 uronate isomerase low > 67
Caulobacter crescentus NA1000 0.44 CCNA_02099 Na+ driven multidrug efflux pump 0.62 CCNA_01557 uronate isomerase low > 66
Azospirillum brasilense Sp245 0.28 AZOBR_RS15325 multidrug transporter 0.70 AZOBR_RS31425 glucuronate isomerase low > 97
Azospirillum sp. SherDot2 0.26 MPMX19_01223 Multidrug resistance protein NorM 0.70 MPMX19_05792 Uronate isomerase low > 112
Echinicola vietnamensis KMM 6221, DSM 17526 0.19 Echvi_2195 putative efflux protein, MATE family 0.17 Echvi_3072 Glucuronate isomerase low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.17 CA265_RS09325 MATE family efflux transporter 0.19 CA265_RS19870 Glucuronate isomerase (EC 5.3.1.12) (from data) low > 88
Pontibacter actiniarum KMM 6156, DSM 19842 0.16 CA264_06370 MATE family efflux transporter 0.17 CA264_13950 glucuronate isomerase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.15 ABZR88_RS09785 MATE family efflux transporter 0.20 ABZR88_RS13040 glucuronate isomerase low > 71
Enterobacter sp. TBS_079 0.15 MPMX20_01973 Multidrug resistance protein MdtK 0.16 MPMX20_04001 Uronate isomerase low > 85
Klebsiella michiganensis M5al 0.15 BWI76_RS16535 MATE family efflux transporter 0.18 BWI76_RS23645 uronate isomerase low > 92
Enterobacter asburiae PDN3 0.14 EX28DRAFT_1660 putative efflux protein, MATE family 0.17 EX28DRAFT_3160 Glucuronate isomerase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.14 GFF3613 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.17 GFF3095 Uronate isomerase (EC 5.3.1.12) low > 78
Escherichia coli HS(pFamp)R (ATCC 700891) 0.14 OHPLBJKB_02061 Multidrug resistance protein MdtK 0.16 OHPLBJKB_00610 Uronate isomerase low > 73
Escherichia coli BL21 0.14 ECD_01634 multidrug efflux system transporter 0.16 ECD_02961 uronate isomerase low > 61
Escherichia coli ECRC100 0.14 OKFHMN_27360 mdtK multidrug efflux MATE transporter MdtK 0.16 OKFHMN_18520 uxaC glucuronate isomerase low > 80
Escherichia fergusonii Becca 0.14 EFB2_02329 Multidrug resistance protein MdtK 0.16 EFB2_00720 Uronate isomerase low > 86
Escherichia coli ECRC98 0.14 JDDGAC_01950 mdtK multidrug efflux MATE transporter MdtK 0.16 JDDGAC_22155 uxaC glucuronate isomerase low > 86
Escherichia coli ECRC99 0.14 KEDOAH_00750 mdtK multidrug efflux MATE transporter MdtK 0.16 KEDOAH_09625 uxaC glucuronate isomerase — —
Escherichia coli Nissle 1917 0.14 ECOLIN_RS09270 multidrug efflux MATE transporter MdtK 0.16 ECOLIN_RS17830 glucuronate isomerase — —
Escherichia coli ECRC101 0.14 MCAODC_18050 mdtK multidrug efflux MATE transporter MdtK 0.16 MCAODC_09035 uxaC glucuronate isomerase low > 87
Escherichia coli BW25113 0.14 b1663 mdtK multidrug efflux protein NorM (NCBI) 0.16 b3092 uxaC glucuronate isomerase (NCBI) low > 76
Escherichia coli ECRC102 0.14 NIAGMN_00705 mdtK multidrug efflux MATE transporter MdtK 0.16 NIAGMN_16285 uxaC glucuronate isomerase — —
Escherichia coli ECRC62 0.14 BNILDI_16670 mdtK multidrug efflux MATE transporter MdtK 0.16 BNILDI_01195 uxaC glucuronate isomerase low > 75
Escherichia coli ECOR27 0.14 NOLOHH_17880 mdtK multidrug efflux MATE transporter MdtK 0.16 NOLOHH_10320 uxaC glucuronate isomerase low > 75
Escherichia coli ECOR38 0.14 HEPCGN_05745 mdtK multidrug efflux MATE transporter MdtK 0.16 HEPCGN_17375 uxaC glucuronate isomerase low > 87
Dickeya dianthicola ME23 0.14 DZA65_RS13155 MATE family efflux transporter 0.16 DZA65_RS02965 glucuronate isomerase low > 75
Serratia liquefaciens MT49 0.13 IAI46_11210 MATE family efflux transporter 0.16 IAI46_22220 glucuronate isomerase low > 86
Dickeya dianthicola 67-19 0.13 HGI48_RS12700 MATE family efflux transporter 0.16 HGI48_RS02800 glucuronate isomerase low > 71
Pectobacterium carotovorum WPP14 0.13 HER17_RS09220 MATE family efflux transporter 0.15 HER17_RS18715 glucuronate isomerase low > 75
Xanthomonas campestris pv. campestris strain 8004 0.13 Xcc-8004.4760.1 Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM 0.65 Xcc-8004.5237.1 Uronate isomerase (EC 5.3.1.12) low > 74
Pantoea sp. MT58 0.13 IAI47_10820 MATE family efflux transporter 0.16 IAI47_02910 glucuronate isomerase low > 76
Rhizobium sp. OAE497 0.12 ABIE40_RS12780 MATE family efflux transporter 0.56 ABIE40_RS00130 glucuronate isomerase low > 107
Rahnella sp. WP5 0.12 EX31_RS13855 MATE family efflux transporter 0.15 EX31_RS12675 glucuronate isomerase low > 89
Alteromonas macleodii MIT1002 0.12 MIT1002_02233 Na(+)/drug antiporter 0.65 MIT1002_02431 Uronate isomerase low > 70
Sinorhizobium meliloti 1021 0.12 SMc01211 hypothetical protein 0.66 SM_b21354 glucuronate isomerase low > 103
Bacteroides thetaiotaomicron VPI-5482 0.12 BT3804 putative transport protein, multidrug efflux protein (NCBI ptt file) 0.19 BT_0823 glucuronate isomerase (RefSeq) low > 81
Sphingomonas koreensis DSMZ 15582 0.12 Ga0059261_2291 putative efflux protein, MATE family 0.65 Ga0059261_2969 Glucuronate isomerase low > 68
Lysobacter sp. OAE881 0.11 ABIE51_RS02170 MATE family efflux transporter 0.67 ABIE51_RS03680 glucuronate isomerase low > 62
Bacteroides stercoris CC31F 0.11 HMPREF1181_RS00200 MATE family efflux transporter 0.19 HMPREF1181_RS14420 glucuronate isomerase low > 56
Bosea sp. OAE506 0.10 ABIE41_RS08515 MATE family efflux transporter 0.65 ABIE41_RS07850 glucuronate isomerase low > 77
Bacteroides ovatus ATCC 8483 0.10 BACOVA_03694 MATE efflux family protein 0.19 BACOVA_02558 glucuronate isomerase low > 94
Phocaeicola vulgatus CL09T03C04 0.10 HMPREF1058_RS02770 MATE family efflux transporter 0.18 HMPREF1058_RS01590 glucuronate isomerase low > 67
Phocaeicola dorei CL03T12C01 0.10 ABI39_RS02110 MATE family efflux transporter 0.18 ABI39_RS15475 glucuronate isomerase low > 72
Parabacteroides merdae CL09T00C40 0.09 HMPREF1078_RS10360 MATE family efflux transporter 0.18 HMPREF1078_RS05615 glucuronate isomerase low > 61
Dickeya dadantii 3937 0.08 DDA3937_RS13645 MATE family efflux transporter 0.16 DDA3937_RS02825 glucuronate isomerase low > 74

Not shown: 47 genomes with orthologs for A4249_RS03825 only; 0 genomes with orthologs for A4249_RS07745 only