Conservation of cofitness between b0049 and b2022 in Escherichia coli BW25113

36 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0049 apaH diadenosinetetraphosphatase (NCBI) 1.0 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.55 11
Escherichia coli ECRC62 1.00 BNILDI_08415 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.99 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli BL21 1.00 ECD_00053 diadenosine tetraphosphatase 0.99 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03607 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical' transl_table=11 0.99 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia coli ECOR27 0.99 NOLOHH_03190 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 57
Escherichia coli ECOR38 0.99 HEPCGN_08835 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.99 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 85
Escherichia coli ECRC101 0.99 OKFHMN_10845 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC101 0.99 MCAODC_01360 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC98 0.99 JDDGAC_14440 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC102 0.99 NIAGMN_08695 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia fergusonii Becca 0.99 EFB2_03994 Bis(5'-nucleosyl)-tetraphosphatase [symmetrical] 0.99 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00275 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.99 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC99 0.98 KEDOAH_17310 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 1.00 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF192 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 0.96 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Enterobacter asburiae PDN3 0.91 EX28DRAFT_3643 Bis(5'nucleosyl)-tetraphosphatase, ApaH 0.91 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 76
Enterobacter sp. TBS_079 0.89 MPMX20_00745 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical 0.92 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB low > 85
Klebsiella michiganensis M5al 0.89 BWI76_RS04510 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 0.88 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 92
Pantoea sp. MT58 0.82 IAI47_16095 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 76
Rahnella sp. WP5 0.79 EX31_RS03790 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 89
Dickeya dadantii 3937 0.79 DDA3937_RS18275 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.84 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 69
Serratia liquefaciens MT49 0.79 IAI46_03235 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Dickeya dianthicola ME23 0.79 DZA65_RS19350 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 0.84 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Dickeya dianthicola 67-19 0.79 HGI48_RS18210 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.84 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Erwinia tracheiphila SCR3 0.76 LU632_RS02740 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Pectobacterium carotovorum WPP14 0.76 HER17_RS02950 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Vibrio cholerae E7946 ATCC 55056 0.53 CSW01_02315 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella sp. ANA-3 0.45 Shewana3_3211 apaH diadenosine tetraphosphatase (RefSeq) 0.63 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.45 SO3641 apaH bis(5'-nucleosyl)-tetraphosphatase (symmetrical) (NCBI ptt file) 0.63 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.69 16
Shewanella loihica PV-4 0.45 Shew_0877 apaH diadenosine tetraphosphatase (RefSeq) 0.66 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.69 26
Shewanella amazonensis SB2B 0.44 Sama_2821 apaH diadenosine tetraphosphatase (RefSeq) 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.42 MIT1002_00779 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB low > 70
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS12295 symmetrical bis(5'-nucleosyl)-tetraphosphatase 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 59
Rhodanobacter denitrificans MT42 0.39 LRK55_RS12030 symmetrical bis(5'-nucleosyl)-tetraphosphatase 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Lysobacter sp. OAE881 0.38 ABIE51_RS05375 symmetrical bis(5'-nucleosyl)-tetraphosphatase 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 62
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.4275.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 74
Rhodanobacter sp. FW510-T8 0.38 OKGIIK_11635 apaH symmetrical bis(5'-nucleosyl)-tetraphosphatase 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 52
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS11280 symmetrical bis(5'-nucleosyl)-tetraphosphatase 0.54 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74

Not shown: 33 genomes with orthologs for b0049 only; 10 genomes with orthologs for b2022 only