Conservation of cofitness between b4238 and b0902 in Escherichia coli BW25113

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4238 nrdD anaerobic ribonucleoside triphosphate reductase (NCBI) 1.0 b0902 pflA pyruvate formate lyase activating enzyme 1 (NCBI) 0.56 6
Escherichia coli BL21 1.00 ECD_04106 anaerobic ribonucleoside-triphosphate reductase 1.00 ECD_00906 pyruvate formate-lyase 1-activating enzyme; [formate-C-acetyltransferase 1]-activating enzyme; PFL activase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03797 Anaerobic ribonucleoside-triphosphate reductase 1.00 OHPLBJKB_02766 Pyruvate formate-lyase 1-activating enzyme low > 73
Escherichia coli ECRC62 1.00 BNILDI_07340 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 BNILDI_20330 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECOR38 1.00 HEPCGN_10100 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 HEPCGN_23005 pflA pyruvate formate lyase 1-activating protein low > 85
Escherichia coli ECOR27 1.00 NOLOHH_04170 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 NOLOHH_22075 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECRC101 1.00 MCAODC_02410 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 MCAODC_24905 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECRC101 1.00 OKFHMN_11905 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 OKFHMN_05515 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECRC98 1.00 JDDGAC_15545 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 JDDGAC_09325 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECRC102 1.00 NIAGMN_09755 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 NIAGMN_03235 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli ECRC99 1.00 KEDOAH_16250 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 KEDOAH_22220 pflA pyruvate formate lyase 1-activating protein — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS24585 anaerobic ribonucleoside-triphosphate reductase 1.00 ECOLIN_RS04780 pyruvate formate lyase 1-activating protein — —
Escherichia fergusonii Becca 1.00 EFB2_04295 Anaerobic ribonucleoside-triphosphate reductase 1.00 EFB2_03162 Pyruvate formate-lyase 1-activating enzyme low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF919 Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) 0.86 GFF3656 Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) low > 78
Klebsiella michiganensis M5al 0.95 BWI76_RS02935 anaerobic ribonucleoside triphosphate reductase 0.98 BWI76_RS09730 pyruvate formate lyase 1-activating protein 0.34 9
Enterobacter sp. TBS_079 0.95 MPMX20_00531 Anaerobic ribonucleoside-triphosphate reductase 0.97 MPMX20_01561 Pyruvate formate-lyase 1-activating enzyme 0.22 72
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3437 ribonucleoside-triphosphate reductase class III catalytic subunit (EC 1.17.4.2) 0.98 EX28DRAFT_2033 pyruvate formate-lyase 1-activating enzyme low > 76
Dickeya dianthicola ME23 0.88 DZA65_RS01880 anaerobic ribonucleoside-triphosphate reductase 0.89 DZA65_RS09970 pyruvate formate lyase 1-activating protein 0.67 2
Dickeya dianthicola 67-19 0.88 HGI48_RS01825 anaerobic ribonucleoside-triphosphate reductase 0.90 HGI48_RS09660 pyruvate formate lyase 1-activating protein 0.56 27
Dickeya dadantii 3937 0.88 DDA3937_RS01875 anaerobic ribonucleoside-triphosphate reductase 0.91 DDA3937_RS09650 pyruvate formate lyase 1-activating protein 0.78 10
Pectobacterium carotovorum WPP14 0.87 HER17_RS19525 anaerobic ribonucleoside-triphosphate reductase 0.92 HER17_RS12310 pyruvate formate lyase 1-activating protein 0.92 10
Serratia liquefaciens MT49 0.87 IAI46_02135 anaerobic ribonucleoside-triphosphate reductase 0.90 IAI46_08605 pyruvate formate lyase 1-activating protein 0.91 3
Rahnella sp. WP5 0.87 EX31_RS08395 anaerobic ribonucleoside-triphosphate reductase 0.90 EX31_RS18470 pyruvate formate lyase 1-activating protein low > 89
Erwinia tracheiphila SCR3 0.81 LU632_RS20975 nrdD anaerobic ribonucleoside-triphosphate reductase 0.88 LU632_RS09770 pflA pyruvate formate lyase 1-activating protein low > 74
Shewanella oneidensis MR-1 0.80 SO2834 nrdD anaerobic ribonucleoside-triphosphate reductase (NCBI ptt file) 0.72 SO2913 pflA pyruvate formate-lyase 1 activating enzyme (NCBI ptt file) 0.87 4
Shewanella sp. ANA-3 0.79 Shewana3_2603 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.72 Shewana3_1554 pflA pyruvate formate lyase-activating enzyme 1 (RefSeq) low > 73
Pantoea sp. MT58 0.79 IAI47_16925 anaerobic ribonucleoside-triphosphate reductase 0.89 IAI47_12885 pyruvate formate lyase 1-activating protein 0.44 11
Shewanella loihica PV-4 0.78 Shew_2449 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.69 Shew_2391 pflA pyruvate formate lyase-activating enzyme 1 (RefSeq) low > 60
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_16800 anaerobic ribonucleoside-triphosphate reductase 0.78 CSW01_09365 pyruvate formate lyase 1-activating protein 0.54 14
Shewanella amazonensis SB2B 0.77 Sama_1275 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.70 Sama_1497 pflA pyruvate formate lyase-activating enzyme 1 (RefSeq) 0.30 59
Bifidobacterium breve UCC2003 0.43 BBR_RS17915 anaerobic ribonucleoside-triphosphate reductase 0.37 BBR_RS14480 pyruvate formate-lyase 1-activating enzyme — —
Fusobacterium nucleatum SB010 0.38 HUW76_02665 anaerobic ribonucleoside-triphosphate reductase 0.42 HUW76_08090 pyruvate formate lyase-activating protein low > 35
Phocaeicola vulgatus CL09T03C04 0.21 HMPREF1058_RS00560 anaerobic ribonucleoside triphosphate reductase 0.40 HMPREF1058_RS18115 pyruvate formate lyase-activating protein low > 67
Phocaeicola dorei CL03T12C01 0.21 ABI39_RS08180 anaerobic ribonucleoside triphosphate reductase 0.40 ABI39_RS14445 pyruvate formate lyase-activating protein low > 72
Bacteroides ovatus ATCC 8483 0.20 BACOVA_01422 anaerobic ribonucleoside-triphosphate reductase 0.38 BACOVA_05596 pyruvate formate-lyase 1-activating enzyme 0.57 12
Bacteroides thetaiotaomicron VPI-5482 0.20 BT1998 anaerobic ribonucleoside-triphosphate reductase (NCBI ptt file) 0.40 BT4737 pyruvate formate-lyase activating enzyme (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.20 HMPREF1181_RS15485 anaerobic ribonucleoside triphosphate reductase 0.37 HMPREF1181_RS12345 pyruvate formate lyase-activating protein low > 56
Parabacteroides merdae CL09T00C40 0.19 HMPREF1078_RS12530 anaerobic ribonucleoside triphosphate reductase 0.45 HMPREF1078_RS04215 pyruvate formate-lyase-activating protein low > 61
Rhodospirillum rubrum S1H 0.09 Rru_A1276 ATP-cone (NCBI) 0.37 Rru_A2999 Radical SAM (NCBI) low > 58

Not shown: 17 genomes with orthologs for b4238 only; 2 genomes with orthologs for b0902 only