Conservation of cofitness between b2838 and b0002 in Escherichia coli BW25113

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2838 lysA diaminopimelate decarboxylase, PLP-binding (NCBI) 1.0 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.93 7
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00891 Diaminopimelate decarboxylase 0.99 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli BL21 1.00 ECD_02686 diaminopimelate decarboxylase, PLP-binding 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.85 3
Escherichia coli ECOR27 1.00 NOLOHH_11830 lysA diaminopimelate decarboxylase 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 57
Escherichia coli ECOR38 1.00 HEPCGN_19565 lysA diaminopimelate decarboxylase 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 85
Escherichia coli ECRC99 1.00 KEDOAH_08185 lysA diaminopimelate decarboxylase 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia fergusonii Becca 1.00 EFB2_01045 Diaminopimelate decarboxylase 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli ECRC62 1.00 BNILDI_10310 lysA diaminopimelate decarboxylase 0.99 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS15930 diaminopimelate decarboxylase 1.00 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.51 12
Escherichia coli ECRC101 0.99 OKFHMN_19945 lysA diaminopimelate decarboxylase 1.00 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC102 0.99 NIAGMN_17715 lysA diaminopimelate decarboxylase 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 0.99 MCAODC_10470 lysA diaminopimelate decarboxylase 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC98 0.99 JDDGAC_23610 lysA diaminopimelate decarboxylase 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Enterobacter sp. TBS_079 0.90 MPMX20_03705 Diaminopimelate decarboxylase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.85 19
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF1323 Diaminopimelate decarboxylase (EC 4.1.1.20) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2916 diaminopimelate decarboxylase 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.89 11
Klebsiella michiganensis M5al 0.88 BWI76_RS23360 diaminopimelate decarboxylase 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.81 16
Serratia liquefaciens MT49 0.78 IAI46_20520 diaminopimelate decarboxylase 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.71 7
Pectobacterium carotovorum WPP14 0.77 HER17_RS03710 diaminopimelate decarboxylase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.92 37
Erwinia tracheiphila SCR3 0.76 LU632_RS06040 lysA diaminopimelate decarboxylase 0.82 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 3
Dickeya dadantii 3937 0.75 DDA3937_RS17425 diaminopimelate decarboxylase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 5
Rahnella sp. WP5 0.75 EX31_RS13275 diaminopimelate decarboxylase 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 6
Dickeya dianthicola ME23 0.75 DZA65_RS18550 diaminopimelate decarboxylase 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.63 45
Pantoea sp. MT58 0.75 IAI47_03860 diaminopimelate decarboxylase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 3
Dickeya dianthicola 67-19 0.74 HGI48_RS17485 diaminopimelate decarboxylase 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 5
Echinicola vietnamensis KMM 6221, DSM 17526 0.26 Echvi_1295 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.94 1
Lysobacter sp. OAE881 0.26 ABIE51_RS13675 diaminopimelate decarboxylase 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella amazonensis SB2B 0.20 Sama_3250 diaminopimelate decarboxylase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.93 45
Shewanella sp. ANA-3 0.19 Shewana3_0390 diaminopimelate decarboxylase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.95 25
Shewanella oneidensis MR-1 0.19 SO4309 lysA diaminopimelate decarboxylase (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.87 69
Shewanella loihica PV-4 0.18 Shew_0322 diaminopimelate decarboxylase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.98 5
Vibrio cholerae E7946 ATCC 55056 0.18 CSW01_00635 diaminopimelate decarboxylase 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS11050 diaminopimelate decarboxylase 0.27 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 1
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS09650 diaminopimelate decarboxylase 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.89 8
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS13545 diaminopimelate decarboxylase 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 22
Bacteroides thetaiotaomicron VPI-5482 0.17 BT1374 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.74 15
Phocaeicola dorei CL03T12C01 0.17 ABI39_RS19950 diaminopimelate decarboxylase 0.31 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.67 16
Phocaeicola vulgatus CL09T03C04 0.17 HMPREF1058_RS06195 diaminopimelate decarboxylase 0.31 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I low > 67
Bacteroides ovatus ATCC 8483 0.17 BACOVA_00215 diaminopimelate decarboxylase 0.27 BACOVA_03021 homoserine dehydrogenase 0.95 19
Mucilaginibacter yixingensis YX-36 DSM 26809 0.16 ABZR88_RS10180 diaminopimelate decarboxylase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Alteromonas macleodii MIT1002 0.16 MIT1002_00160 Diaminopimelate decarboxylase 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.84 20

Not shown: 59 genomes with orthologs for b2838 only; 1 genomes with orthologs for b0002 only