Conservation of cofitness between b1232 and b0002 in Escherichia coli BW25113

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1232 purU formyltetrahydrofolate deformylase (NCBI) 1.0 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.75 9
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02453 Formyltetrahydrofolate deformylase 0.99 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia fergusonii Becca 1.00 EFB2_02694 Formyltetrahydrofolate deformylase 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli ECOR27 1.00 NOLOHH_20480 purU formyltetrahydrofolate deformylase 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 57
Escherichia coli ECOR38 1.00 HEPCGN_25030 purU formyltetrahydrofolate deformylase 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 85
Escherichia coli BL21 1.00 ECD_01208 formyltetrahydrofolate hydrolase 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 60
Escherichia coli Nissle 1917 1.00 ECOLIN_RS07460 formyltetrahydrofolate deformylase 1.00 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 52
Escherichia coli ECRC102 1.00 NIAGMN_27665 purU formyltetrahydrofolate deformylase 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 1.00 OKFHMN_28570 purU formyltetrahydrofolate deformylase 1.00 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 1.00 MCAODC_21690 purU formyltetrahydrofolate deformylase 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC98 1.00 JDDGAC_06005 purU formyltetrahydrofolate deformylase 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC99 1.00 KEDOAH_25565 purU formyltetrahydrofolate deformylase 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC62 0.99 BNILDI_18635 purU formyltetrahydrofolate deformylase 0.99 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF2756 Formyltetrahydrofolate deformylase (EC 3.5.1.10) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Klebsiella michiganensis M5al 0.96 BWI76_RS17290 formyltetrahydrofolate deformylase 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.46 2
Enterobacter sp. TBS_079 0.95 MPMX20_02596 Formyltetrahydrofolate deformylase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.53 32
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0858 formyltetrahydrofolate deformylase 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) low > 76
Serratia liquefaciens MT49 0.90 IAI46_14265 formyltetrahydrofolate deformylase 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I low > 86
Pectobacterium carotovorum WPP14 0.90 HER17_RS11065 formyltetrahydrofolate deformylase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.75 33
Pantoea sp. MT58 0.90 IAI47_09010 formyltetrahydrofolate deformylase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 38
Dickeya dadantii 3937 0.90 DDA3937_RS10325 formyltetrahydrofolate deformylase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 10
Erwinia tracheiphila SCR3 0.89 LU632_RS12940 purU formyltetrahydrofolate deformylase 0.82 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.62 61
Dickeya dianthicola ME23 0.89 DZA65_RS10810 formyltetrahydrofolate deformylase 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.57 69
Dickeya dianthicola 67-19 0.89 HGI48_RS10335 formyltetrahydrofolate deformylase 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I low > 71
Rahnella sp. WP5 0.89 EX31_RS10115 formyltetrahydrofolate deformylase 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 24
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_09940 formyltetrahydrofolate deformylase 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella sp. ANA-3 0.70 Shewana3_2821 purU formyltetrahydrofolate deformylase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.53 54
Shewanella amazonensis SB2B 0.69 Sama_1134 purU formyltetrahydrofolate deformylase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.40 25
Shewanella oneidensis MR-1 0.68 SO1624 purU formyltetrahydrofolate deformylase (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.65 Shew_2640 purU formyltetrahydrofolate deformylase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.52 10
Mucilaginibacter yixingensis YX-36 DSM 26809 0.50 ABZR88_RS14140 formyltetrahydrofolate deformylase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Pedobacter sp. GW460-11-11-14-LB5 0.45 CA265_RS21155 formyltetrahydrofolate deformylase 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.41 Echvi_1543 formyltetrahydrofolate deformylase 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.34 10
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS06160 formyltetrahydrofolate deformylase 0.31 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.70 47
Phocaeicola dorei CL03T12C01 0.39 ABI39_RS19915 formyltetrahydrofolate deformylase 0.31 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I low > 72
Bacteroides thetaiotaomicron VPI-5482 0.39 BT1381 formyltetrahydrofolate deformylase (NCBI ptt file) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.79 42
Bacteroides ovatus ATCC 8483 0.39 BACOVA_00222 formyltetrahydrofolate deformylase 0.27 BACOVA_03021 homoserine dehydrogenase 0.91 15
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS11085 formyltetrahydrofolate deformylase 0.27 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.78 21
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.395.1 Formyltetrahydrofolate deformylase (EC 3.5.1.10) 0.34 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.83 1
Alteromonas macleodii MIT1002 0.36 MIT1002_00404 Formyltetrahydrofolate deformylase 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I low > 70
Lysobacter sp. OAE881 0.35 ABIE51_RS07700 formyltetrahydrofolate deformylase 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62

Not shown: 49 genomes with orthologs for b1232 only; 1 genomes with orthologs for b0002 only