| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS02610 | | DNA-binding response regulator | insig. | 100 | 100 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS17360 | | LytTR family DNA-binding domain-containing protein | sig. | 55 | 98 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS23150 | | DNA-binding response regulator | sig. | 51 | 99 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04490 | | DNA-binding response regulator | insig. | 49 | 98 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07520 | | DNA-binding response regulator | insig. | 42 | 97 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_13010 | | DNA-binding response regulator | sig. | 44 | 98 |
| o | Cellulophaga baltica 18 | M666_RS16895 | | LytTR family DNA-binding domain-containing protein | insig. | 42 | 95 |
| | Cellulophaga baltica 18 | M666_RS14090 | | LytTR family DNA-binding domain-containing protein | insig. | 40 | 97 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08345 | | DNA-binding response regulator | insig. | 41 | 98 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1319 | | two-component system response regulator (NCBI ptt file) | insig. | 42 | 96 |
| | Cellulophaga baltica 18 | M666_RS16545 | | LytTR family DNA-binding domain-containing protein | insig. | 37 | 100 |
| | Cellulophaga baltica 18 | M666_RS16390 | | response regulator transcription factor | insig. | 43 | 98 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS16600 | | hypothetical protein | insig. | 38 | 98 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03960 | | LytTr DNA-binding domain protein | insig. | 40 | 95 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08575 | | LytTR family DNA-binding domain-containing protein | insig. | 43 | 95 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3828 | | Response regulator of the LytR/AlgR family | insig. | 40 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS05650 | | LytTR family DNA-binding domain-containing protein | insig. | 39 | 97 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS12495 | | response regulator transcription factor | cofit | 38 | 95 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS02920 | | LytTR family DNA-binding domain-containing protein | insig. | 38 | 95 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1457 | | two-component system response regulator (NCBI ptt file) | insig. | 38 | 96 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2692 | | Response regulator of the LytR/AlgR family | insig. | 41 | 97 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS16410 | | LytTR family DNA-binding domain-containing protein | insig. | 38 | 98 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1217 | | two-component system response regulator (NCBI ptt file) | strong | 38 | 95 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04152 | | response regulator receiver domain protein | insig. | 38 | 96 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4566 | | two-component system response regulator protein (NCBI ptt file) | insig. | 37 | 98 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09800 | | DNA-binding response regulator | sig. | 38 | 94 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_06915 | | DNA-binding response regulator | insig. | 39 | 96 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS17365 | | LytTR family DNA-binding domain-containing protein | insig. | 37 | 99 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3036 | | Response regulator of the LytR/AlgR family | insig. | 39 | 95 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04517 | | response regulator receiver domain protein | insig. | 37 | 95 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02521 | | response regulator receiver domain protein | insig. | 39 | 96 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS17125 | | DNA-binding response regulator | insig. | 39 | 93 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS00315 | | DNA-binding response regulator | insig. | 38 | 95 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1794 | | two-component system response regulator (NCBI ptt file) | insig. | 36 | 95 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS05725 | | LytTR family DNA-binding domain-containing protein | insig. | 36 | 94 |
| | Cellulophaga baltica 18 | M666_RS17925 | | LytTR family DNA-binding domain-containing protein | strong | 35 | 95 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS14405 | | response regulator transcription factor | insig. | 34 | 95 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS18080 | | response regulator transcription factor | insig. | 34 | 95 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4158 | | Response regulator of the LytR/AlgR family | insig. | 36 | 95 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS17690 | | DNA-binding response regulator | strong | 37 | 98 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS07585 | | DNA-binding response regulator | insig. | 34 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS06365 | | LytTR family DNA-binding domain-containing protein | insig. | 33 | 99 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS13935 | | DNA-binding response regulator | insig. | 33 | 94 |
| | Cellulophaga baltica 18 | M666_RS11950 | | LytTR family DNA-binding domain-containing protein | strong | 33 | 96 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11655 | | hypothetical protein | insig. | 32 | 95 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS10395 | | hypothetical protein | cofit | 31 | 95 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_16125 | | DNA-binding response regulator | sig. | 34 | 87 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS05660 | | DNA-binding response regulator | strong | 29 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS07120 | | LytTR family DNA-binding domain-containing protein | insig. | 30 | 95 |
| | Cellulophaga baltica 18 | M666_RS01195 | | LytTR family DNA-binding domain-containing protein | insig. | 34 | 86 |
| | Methylophilus sp. DMC18 | GFF2152 | | Transcriptional regulatory protein YpdB | cofit | 34 | 87 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS10975 | | DNA-binding response regulator | insig. | 34 | 87 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS18055 | | LytTR family DNA-binding domain-containing protein | insig. | 33 | 87 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0037 | | Response regulator of the LytR/AlgR family | insig. | 31 | 87 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0251 | | two component transcriptional regulator, LytTR family | cofit | 33 | 85 |
| | Cellulophaga baltica 18 | M666_RS06060 | | LytTR family DNA-binding domain-containing protein | insig. | 31 | 97 |
| | Sphingobium sp. HT1-2 | GFF1691 | | Two-component transcriptional response regulator, LuxR family | insig. | 29 | 93 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1140 | | Response regulator of the LytR/AlgR family | strong | 30 | 86 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS20425 | | LytTR family DNA-binding domain-containing protein | insig. | 31 | 86 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_03625 | | DNA-binding response regulator | insig. | 29 | 95 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_0437 | | two component transcriptional regulator, LytTR family | insig. | 29 | 94 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_0238 | | two component transcriptional regulator, LytTR family | insig. | 29 | 95 |
| | Enterobacter sp. TBS_079 | MPMX20_03092 | | Transcriptional regulatory protein BtsR | sig. | 28 | 94 |
| | Shewanella sp. ANA-3 | Shewana3_2594 | | putative two-component response-regulatory protein YehT (RefSeq) | insig. | 30 | 94 |
| | Shewanella amazonensis SB2B | Sama_1281 | | putative two-component response-regulatory protein YehT (RefSeq) | strong | 29 | 95 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS24520 | | hypothetical protein | insig. | 31 | 90 |
| | Escherichia coli ECOR27 | NOLOHH_14045 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC100 | OKFHMN_22360 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC101 | MCAODC_12890 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC102 | NIAGMN_20135 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC62 | BNILDI_12900 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC98 | JDDGAC_26325 | ypdB | two-component system response regulator YpdB | insig. | 28 | 97 |
| | Escherichia coli ECRC99 | KEDOAH_05860 | ypdB | two-component system response regulator YpdB | no data | 28 | 97 |
| | Escherichia coli ECOR38 | HEPCGN_21570 | ypdB | two-component system response regulator YpdB | insig. | 29 | 97 |
| | Escherichia coli BL21 | ECD_02291 | | response regulator activating yhjX; pyruvate-responsive YpdAB two-component system | insig. | 28 | 97 |
| | Escherichia fergusonii Becca | EFB2_01493 | | Transcriptional regulatory protein YpdB | insig. | 28 | 97 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01340 | | Transcriptional regulatory protein YpdB | insig. | 28 | 97 |
| | Escherichia coli BW25113 | b2381 | ypdB | predicted response regulator in two-component system withYpdA (NCBI) | insig. | 28 | 97 |
| | Fusobacterium nucleatum SB010 | HUW76_02600 | | response regulator transcription factor | strong | 28 | 87 |
| | Shewanella oneidensis MR-1 | SO2823 | | response regulator (NCBI ptt file) | strong | 30 | 94 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS13700 | | two-component system response regulator YpdB | no data | 29 | 97 |
| | Sphingobium sp. HT1-2 | GFF230 | | Two-component transcriptional response regulator, LuxR family | no data | 28 | 88 |
| | Enterobacter sp. TBS_079 | MPMX20_03280 | | Transcriptional regulatory protein YpdB | sig. | 28 | 97 |
| | Klebsiella michiganensis M5al | BWI76_RS20505 | | DNA-binding response regulator | insig. | 30 | 89 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_27365 | | DNA-binding response regulator | insig. | 28 | 89 |
| | Dickeya dianthicola ME23 | DZA65_RS17550 | | two-component system response regulator BtsR | insig. | 29 | 94 |
| | Pantoea sp. MT58 | IAI47_05560 | | response regulator transcription factor | insig. | 27 | 97 |
| | Alteromonas macleodii MIT1002 | MIT1002_01990 | | Transcriptional regulatory protein YehT | insig. | 27 | 95 |
| | Cellulophaga baltica 18 | M666_RS07845 | | LytTR family DNA-binding domain-containing protein | insig. | 28 | 87 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS20110 | | response regulator transcription factor | insig. | 27 | 97 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF738 | | Autolysis response regulater LytR | cofit | 26 | 88 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01125 | | LytTR family transcriptional regulator DNA-binding domain-containing protein | insig. | 30 | 85 |
| | Klebsiella michiganensis M5al | BWI76_RS19470 | | DNA-binding response regulator | strong | 26 | 94 |
| | Dickeya dadantii 3937 | DDA3937_RS16365 | | two-component system response regulator BtsR | insig. | 28 | 94 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS12350 | | hypothetical protein | insig. | 26 | 97 |
| | Dickeya dianthicola 67-19 | HGI48_RS16465 | | two-component system response regulator BtsR | insig. | 28 | 94 |
| | Rahnella sp. WP5 | EX31_RS00780 | | two-component system response regulator BtsR | insig. | 28 | 94 |
| | Escherichia coli BL21 | ECD_02054 | | putative response regulator in two-component system withYehU | insig. | 26 | 94 |
| | Escherichia fergusonii Becca | EFB2_01731 | | Transcriptional regulatory protein BtsR | insig. | 26 | 94 |
| | Escherichia coli ECOR27 | NOLOHH_15235 | btsR | two-component system response regulator BtsR | insig. | 26 | 94 |