Conservation of cofitness between SMc00377 and SMc02868 in Sinorhizobium meliloti 1021

24 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Sinorhizobium meliloti 1021	1.0	SMc00377		hypothetical protein	1.0	SMc02868		multidrug efflux system protein	0.32	5
Sphingomonas koreensis DSMZ 15582	0.27	Ga0059261_0738		Predicted transcriptional regulators	0.34	Ga0059261_0560		RND family efflux transporter, MFP subunit	low	> 68
Paraburkholderia bryophila 376MFSha3.1	0.27	H281DRAFT_03495		transcriptional regulator, XRE family	0.35	H281DRAFT_01000		membrane fusion protein, multidrug efflux system	low	> 103
Lysobacter sp. OAE881	0.27	ABIE51_RS06320		helix-turn-helix transcriptional regulator	0.28	ABIE51_RS17985		efflux RND transporter periplasmic adaptor subunit	—	—
Ralstonia sp. UNC404CL21Col	0.27	ABZR87_RS03115		helix-turn-helix transcriptional regulator	0.37	ABZR87_RS05310		efflux RND transporter periplasmic adaptor subunit	low	> 80
Paraburkholderia graminis OAS925	0.27	ABIE53_004095		transcriptional regulator with XRE-family HTH domain	0.31	ABIE53_003409		membrane fusion protein (multidrug efflux system)	low	> 113
Paraburkholderia sabiae LMG 24235	0.27	QEN71_RS33545		helix-turn-helix transcriptional regulator	0.35	QEN71_RS29870		efflux RND transporter periplasmic adaptor subunit	low	> 153
Burkholderia phytofirmans PsJN	0.26	BPHYT_RS23010		transcriptional regulator	0.35	BPHYT_RS34600		hemolysin D	low	> 109
Bosea sp. OAE506	0.26	ABIE41_RS03500		helix-turn-helix transcriptional regulator	0.36	ABIE41_RS01600		efflux RND transporter periplasmic adaptor subunit	low	> 77
Dyella japonica UNC79MFTsu3.2	0.26	ABZR86_RS19660		helix-turn-helix transcriptional regulator	0.38	ABZR86_RS18280		efflux RND transporter periplasmic adaptor subunit	low	> 74
Agrobacterium fabrum C58	0.26	Atu0743		hypothetical protein	0.55	Atu3203		RND multidrug efflux membrane permease	low	> 89
Rhizobium sp. OAE497	0.26	ABIE40_RS11140		helix-turn-helix transcriptional regulator	0.34	ABIE40_RS24220		efflux RND transporter periplasmic adaptor subunit	low	> 107
Variovorax sp. OAS795	0.24	ABID97_RS08540		helix-turn-helix transcriptional regulator	0.39	ABID97_RS00320		efflux RND transporter periplasmic adaptor subunit	low	> 91
Acidovorax sp. GW101-3H11	0.24	Ac3H11_1138		Predicted transcriptional regulators	0.36	Ac3H11_4449		RND efflux system, membrane fusion protein CmeA	low	> 79
Azospirillum sp. SherDot2	0.23	MPMX19_05933		hypothetical protein	0.39	MPMX19_05883		Multidrug resistance protein MexA	—	—
Cupriavidus basilensis FW507-4G11	0.23	RR42_RS28910		XRE family transcriptional regulator	0.36	RR42_RS20645		MexE family multidrug efflux RND transporter periplasmic adaptor subunit	—	—
Rhodopseudomonas palustris CGA009	0.22	TX73_020050		helix-turn-helix domain-containing protein	0.52	TX73_020240		efflux RND transporter periplasmic adaptor subunit	low	> 86
Azospirillum brasilense Sp245	0.22	AZOBR_RS28605		XRE family transcriptional regulator	0.37	AZOBR_RS30180		hemolysin D	—	—
Pseudomonas simiae WCS417	0.22	PS417_14830		Cro/Cl family transcriptional regulator	0.41	PS417_12590		RND transporter	—	—
Pseudomonas putida KT2440	0.22	PP_2653		Transcriptional regulator, Cro/CI family	0.39	PP_3455		Multidrug efflux RND membrane fusion protein	low	> 96
Hydrogenophaga sp. GW460-11-11-14-LB1	0.21	GFF3378		transcriptional regulator, XRE family	0.38	GFF3839		RND efflux system, membrane fusion protein CmeA	low	> 90
Pseudomonas fluorescens SBW25	0.21	PFLU_RS16845		helix-turn-helix transcriptional regulator	0.41	PFLU_RS13285		efflux RND transporter periplasmic adaptor subunit	low	> 109
Pseudomonas fluorescens SBW25-INTG	0.21	PFLU_RS16845		helix-turn-helix transcriptional regulator	0.41	PFLU_RS13285		efflux RND transporter periplasmic adaptor subunit	low	> 109
Pseudomonas fluorescens FW300-N2C3	0.21	AO356_20715		Cro/Cl family transcriptional regulator	0.41	AO356_28725		RND transporter	—	—
Pseudomonas sp. S08-1	0.21	OH686_11600		protein	0.40	OH686_16045		Multidrug efflux system, membrane fusion component	low	> 80

Not shown: 1 genomes with orthologs for SMc00377 only; 58 genomes with orthologs for SMc02868 only