Conservation of cofitness between Rv1058 and Rv1085c in Mycobacterium tuberculosis H37Rv

21 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Mycobacterium tuberculosis H37Rv	1.0	Rv1058		Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	1.0	Rv1085c		Possible hemolysin-like protein	0.53	10
Variovorax sp. SCN45	0.43	GFF2114		3-methylmercaptopropionyl-CoA ligase (EC 6.2.1.44) of DmdB2 type	0.17	GFF727		FIG01964566: Predicted membrane protein, hemolysin III homolog	low	> 127
Cupriavidus basilensis FW507-4G11	0.40	RR42_RS19810		long-chain fatty acid--CoA ligase	0.15	RR42_RS36990		hemolysin III	low	> 128
Acidovorax sp. GW101-3H11	0.40	Ac3H11_4302		Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)	0.14	Ac3H11_4296		COG1272: Predicted membrane protein hemolysin III homolog	low	> 79
Ralstonia sp. UNC404CL21Col	0.39	ABZR87_RS12625		3-(methylthio)propionyl-CoA ligase	0.12	ABZR87_RS02015		hemolysin III family protein	low	> 80
Rhodopseudomonas palustris CGA009	0.38	TX73_023060		fatty-acid--CoA ligase	0.18	TX73_008140		hemolysin III family protein	low	> 86
Rhodospirillum rubrum S1H	0.38	Rru_A1316		AMP-dependent synthetase and ligase (NCBI)	0.16	Rru_A0661		Hly-III related proteins (NCBI)	low	> 58
Pseudomonas stutzeri RCH2	0.36	Psest_2444		Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	0.17	Psest_3779		channel protein, hemolysin III family	low	> 67
Pseudomonas fluorescens GW456-L13	0.30	PfGW456L13_4890		Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)	0.16	PfGW456L13_1038		COG1272: Predicted membrane protein hemolysin III homolog	low	> 87
Pseudomonas putida KT2440	0.30	PP_0763		Medium-chain-fatty-acid CoA ligase	0.16	PP_4986		Channel protein, hemolysin III family	low	> 96
Pseudomonas fluorescens FW300-N2E2	0.30	Pf6N2E2_3244		Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)	0.16	Pf6N2E2_4629		COG1272: Predicted membrane protein hemolysin III homolog	low	> 103
Pseudomonas sp. S08-1	0.29	OH686_06325		Medium-chain-fatty-acid--CoA ligase	0.16	OH686_06045		Predicted membrane protein, hemolysin III-related	low	> 80
Pseudomonas fluorescens FW300-N2E3	0.29	AO353_15010		long-chain fatty acid--CoA ligase	0.17	AO353_08075		hemolysin III	low	> 101
Pseudomonas fluorescens FW300-N2C3	0.29	AO356_06910		long-chain fatty acid--CoA ligase	0.17	AO356_13560		hemolysin III	low	> 104
Pseudomonas sp. RS175	0.29	PFR28_03620		Long-chain-fatty-acid--CoA ligase	0.16	PFR28_04213		hypothetical protein	low	> 88
Pseudomonas syringae pv. syringae B728a ΔmexB	0.29	Psyr_0990		AMP-dependent synthetase and ligase	0.18	Psyr_0452		HylII	low	> 86
Pseudomonas syringae pv. syringae B728a	0.29	Psyr_0990		AMP-dependent synthetase and ligase	0.18	Psyr_0452		HylII	low	> 86
Pseudomonas simiae WCS417	0.29	PS417_04540		long-chain fatty acid--CoA ligase	0.17	PS417_26570		hemolysin III	low	> 88
Pseudomonas fluorescens FW300-N1B4	0.29	Pf1N1B4_5982		Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)	0.16	Pf1N1B4_2371		COG1272: Predicted membrane protein hemolysin III homolog	low	> 87
Marinobacter adhaerens HP15	0.28	HP15_2595		acyl-CoA synthetase	0.16	HP15_2974		channel protein, hemolysin III family	low	> 73
Acinetobacter radioresistens SK82	0.21	MPMX26_00552		Long-chain-fatty-acid--CoA ligase	0.16	MPMX26_00606		hypothetical protein	low	> 36
Dinoroseobacter shibae DFL-12	0.20	Dshi_0833		AMP-dependent synthetase and ligase (RefSeq)	0.13	Dshi_2910		Hly-III family protein (RefSeq)	low	> 64

Not shown: 22 genomes with orthologs for Rv1058 only; 9 genomes with orthologs for Rv1085c only