Conservation of cofitness between PP_4999 and PP_3999 in Pseudomonas putida KT2440

25 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4999 dihydroorotase-like protein 1.0 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.45 10
Pseudomonas simiae WCS417 0.85 PS417_26705 dihydroorotase 0.83 PS417_16465 sirohydrochlorin ferrochelatase — —
Pseudomonas syringae pv. syringae B728a 0.85 Psyr_0481 dihydroorotase 0.82 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.85 Psyr_0481 dihydroorotase 0.82 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.85 PFLU_RS28350 dihydroorotase 0.84 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase — —
Pseudomonas fluorescens SBW25 0.85 PFLU_RS28350 dihydroorotase 0.84 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase — —
Pseudomonas fluorescens GW456-L13 0.84 PfGW456L13_1015 Dihydroorotase (EC 3.5.2.3) 0.84 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Pseudomonas fluorescens FW300-N1B4 0.84 Pf1N1B4_2346 Dihydroorotase (EC 3.5.2.3) 0.83 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Pseudomonas fluorescens FW300-N2E2 0.81 Pf6N2E2_4605 Dihydroorotase (EC 3.5.2.3) 0.84 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Pseudomonas fluorescens FW300-N2E3 0.81 AO353_08140 dihydroorotase 0.84 AO353_27625 sirohydrochlorin ferrochelatase — —
Pseudomonas sp. RS175 0.81 PFR28_04238 Dihydroorotase-like protein 0.84 PFR28_02603 Siroheme synthase — —
Pseudomonas fluorescens FW300-N2C3 0.81 AO356_13445 dihydroorotase 0.84 AO356_22200 sirohydrochlorin ferrochelatase low > 104
Pseudomonas stutzeri RCH2 0.80 Psest_0290 dihydroorotase, multifunctional complex type 0.77 Psest_2037 uroporphyrin-III C-methyltransferase — —
Pseudomonas sp. S08-1 0.78 OH686_10945 Dihydroorotase 0.77 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase — —
Rhodospirillum rubrum S1H 0.35 Rru_A3191 Dihydroorotase multifunctional complex type (NCBI) 0.30 Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) low > 58
Acinetobacter radioresistens SK82 0.33 MPMX26_01100 Dihydroorotase-like protein 0.55 MPMX26_00706 Siroheme synthase — —
Bosea sp. OAE506 0.32 ABIE41_RS17225 dihydroorotase 0.30 ABIE41_RS15910 siroheme synthase CysG — —
Rhodopseudomonas palustris CGA009 0.31 TX73_016125 dihydroorotase 0.35 TX73_021850 siroheme synthase CysG — —
Sinorhizobium meliloti 1021 0.29 SMc01361 dihydroorotase 0.34 SMc01053 siroheme synthase 0.71 56
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS04255 dihydroorotase 0.36 A4249_RS09675 siroheme synthase CysG — —
Dinoroseobacter shibae DFL-12 0.27 Dshi_3094 dihydroorotase, multifunctional complex type (RefSeq) 0.28 Dshi_1671 uroporphyrin-III C-methyltransferase (RefSeq) low > 64
Rhizobium sp. OAE497 0.27 ABIE40_RS07380 dihydroorotase 0.33 ABIE40_RS09140 siroheme synthase CysG — —
Agrobacterium fabrum C58 0.26 Atu1307 dihydroorotase 0.33 Atu1454 siroheme synthase 0.78 45
Mycobacterium tuberculosis H37Rv 0.25 Rv1381 Probable dihydroorotase PyrC (DHOase) 0.20 Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase — —
Lysobacter sp. OAE881 0.14 ABIE51_RS13460 dihydroorotase 0.40 ABIE51_RS15855 siroheme synthase CysG — —
Dyella japonica UNC79MFTsu3.2 0.14 ABZR86_RS08760 dihydroorotase 0.42 ABZR86_RS05880 siroheme synthase CysG — —

Not shown: 37 genomes with orthologs for PP_4999 only; 31 genomes with orthologs for PP_3999 only