Conservation of cofitness between NOLOHH_15535 and NOLOHH_11820 in Escherichia coli ECOR27

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 NOLOHH_11820 ygeA amino acid racemase 0.65 14
Escherichia coli ECRC98 1.00 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 JDDGAC_23600 ygeA amino acid racemase low > 86
Escherichia coli ECRC62 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 BNILDI_10300 ygeA amino acid racemase low > 75
Escherichia coli ECRC101 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_10460 ygeA amino acid racemase low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_08195 ygeA amino acid racemase — —
Escherichia coli ECRC102 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_17705 ygeA amino acid racemase — —
Escherichia coli ECRC100 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_19935 ygeA amino acid racemase low > 80
Escherichia coli BL21 1.00 ECD_01981 multidrug efflux system, subunit C 1.00 ECD_02688 Asp/Glu_racemase family protein low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_00889 Putative racemase YgeA low > 73
Escherichia coli BW25113 1.00 b2076 mdtC multidrug efflux system, subunit C (NCBI) 0.99 b2840 ygeA predicted racemase (NCBI) low > 76
Escherichia coli ECOR38 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 HEPCGN_19575 ygeA amino acid racemase low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 1.00 ECOLIN_RS15940 amino acid racemase — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 1.00 EFB2_01043 L-aspartate/glutamate-specific racemase low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.83 EX28DRAFT_2918 aspartate racemase low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.84 MPMX20_03707 L-aspartate/glutamate-specific racemase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.83 GFF1325 Aspartate racemase (EC 5.1.1.13) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.82 BWI76_RS23370 aspartate/glutamate racemase low > 92
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.61 IAI46_18225 aspartate/glutamate racemase family protein low > 86
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.62 HER17_RS15295 aspartate/glutamate racemase family protein low > 75
Pantoea sp. MT58 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC 0.59 IAI47_18995 aspartate/glutamate racemase family protein low > 76
Dickeya dianthicola 67-19 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC 0.13 HGI48_RS07250 aspartate/glutamate racemase family protein low > 71
Dickeya dadantii 3937 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC 0.13 DDA3937_RS07385 aspartate/glutamate racemase family protein low > 74
Dickeya dianthicola ME23 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC 0.13 DZA65_RS07760 aspartate/glutamate racemase family protein low > 75
Ralstonia solanacearum GMI1000 0.63 RS_RS22920 nodulation protein 0.22 RS_RS01050 aspartate/glutamate racemase family protein low > 80
Acidovorax sp. GW101-3H11 0.56 Ac3H11_3620 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.12 Ac3H11_1641 Aspartate racemase (EC 5.1.1.13) low > 79
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.57 OH686_18340 Aspartate racemase low > 80
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.50 PFLU_RS14675 aspartate/glutamate racemase family protein low > 109
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.50 PFLU_RS14675 aspartate/glutamate racemase family protein low > 109
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.62 EX31_RS20045 aspartate/glutamate racemase family protein low > 89
Pseudomonas simiae WCS417 0.52 PS417_12750 acriflavine resistance protein B 0.52 PS417_13940 racemase low > 88
Castellaniella sp019104865 MT123 0.52 ABCV34_RS14625 efflux RND transporter permease subunit 0.60 ABCV34_RS07215 aspartate/glutamate racemase family protein low > 48
Pseudomonas sp. RS175 0.51 PFR28_02193 Multidrug resistance protein MdtC 0.54 PFR28_02199 L-aspartate/glutamate-specific racemase low > 88
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein 0.25 GFF2459 Aspartate racemase (EC 5.1.1.13) low > 90
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_06491 multidrug efflux pump 0.55 H281DRAFT_00459 aspartate racemase low > 103
Azospirillum brasilense Sp245 0.44 AZOBR_RS14670 multidrug transporter 0.44 AZOBR_RS21090 aspartate racemase low > 97
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS07780 nodulation protein 0.55 BPHYT_RS12885 aspartate racemase low > 109
Bosea sp. OAE506 0.41 ABIE41_RS20140 efflux RND transporter permease subunit 0.52 ABIE41_RS12895 aspartate/glutamate racemase family protein low > 77
Agrobacterium fabrum C58 0.39 Atu3274 AcrB/AcrD/AcrF family protein 0.44 Atu3073 aspartate racemase low > 89
Variovorax sp. OAS795 0.39 ABID97_RS06490 efflux RND transporter permease subunit 0.24 ABID97_RS21720 amino acid racemase low > 91
Rhizobium sp. OAE497 0.38 ABIE40_RS05760 efflux RND transporter permease subunit 0.48 ABIE40_RS11390 aspartate/glutamate racemase family protein low > 107
Sinorhizobium meliloti 1021 0.23 SMc01457 transport transmembrane protein 0.44 SMc01404 aspartate racemase low > 103
Caulobacter crescentus NA1000 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.52 CCNA_03387 aspartate racemase low > 66
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.52 CCNA_03387 aspartate racemase low > 67
Fusobacterium nucleatum SB010 0.16 HUW76_07660 efflux RND transporter permease subunit 0.56 HUW76_08040 aspartate/glutamate racemase family protein low > 35

Not shown: 19 genomes with orthologs for NOLOHH_15535 only; 18 genomes with orthologs for NOLOHH_11820 only