Conservation of cofitness between GFF409 and GFF655 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF409 L-lactate dehydrogenase (EC 1.1.2.3) 1.0 GFF655 DNA-binding domain of ModE / Molybdate-binding domain of ModE 0.46 7
Escherichia coli BW25113 0.95 b3605 lldD L-lactate dehydrogenase, FMN-linked (NCBI) 0.83 b0761 modE DNA-binding transcriptional dual regulator (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_00094 L-lactate dehydrogenase 0.83 OHPLBJKB_02952 Transcriptional regulator ModE low > 73
Escherichia coli ECRC98 0.95 JDDGAC_19395 lldD quinone-dependent L-lactate dehydrogenase 0.83 JDDGAC_10360 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECRC101 0.95 MCAODC_06280 lldD quinone-dependent L-lactate dehydrogenase 0.83 MCAODC_25925 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECRC102 0.95 NIAGMN_13530 lldD quinone-dependent L-lactate dehydrogenase 0.83 NIAGMN_04755 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECRC99 0.95 KEDOAH_12380 lldD quinone-dependent L-lactate dehydrogenase 0.83 KEDOAH_21260 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECRC62 0.95 BNILDI_03865 lldD quinone-dependent L-lactate dehydrogenase 0.83 BNILDI_21130 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECOR27 0.95 NOLOHH_07650 lldD quinone-dependent L-lactate dehydrogenase 0.83 NOLOHH_23135 modE molybdenum-dependent transcriptional regulator low > 57
Escherichia coli ECRC101 0.95 OKFHMN_15770 lldD quinone-dependent L-lactate dehydrogenase 0.83 OKFHMN_06705 modE molybdenum-dependent transcriptional regulator — —
Escherichia coli ECOR38 0.95 HEPCGN_14610 lldD quinone-dependent L-lactate dehydrogenase 0.83 HEPCGN_01570 modE molybdenum-dependent transcriptional regulator low > 85
Escherichia coli Nissle 1917 0.95 ECOLIN_RS20580 quinone-dependent L-lactate dehydrogenase 0.83 ECOLIN_RS04055 molybdenum-dependent transcriptional regulator low > 52
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3855 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases 0.78 EX28DRAFT_2234 ModE molybdate transport repressor domain/molybdenum-pterin binding domain low > 76
Enterobacter sp. TBS_079 0.94 MPMX20_00129 L-lactate dehydrogenase 0.76 MPMX20_01388 DNA-binding transcriptional dual regulator ModE low > 85
Escherichia fergusonii Becca 0.93 EFB2_00205 L-lactate dehydrogenase 0.83 EFB2_03345 DNA-binding transcriptional dual regulator ModE low > 86
Pantoea sp. MT58 0.89 IAI47_15020 FMN-dependent L-lactate dehydrogenase LldD 0.57 IAI47_13575 molybdenum-dependent transcriptional regulator low > 76
Rahnella sp. WP5 0.83 EX31_RS00640 FMN-dependent L-lactate dehydrogenase LldD 0.62 EX31_RS23600 molybdenum-dependent transcriptional regulator low > 89
Serratia liquefaciens MT49 0.82 IAI46_20620 FMN-dependent L-lactate dehydrogenase LldD 0.61 IAI46_06450 molybdenum-dependent transcriptional regulator low > 86
Pseudomonas putida KT2440 0.81 PP_4736 L-lactate dehydrogenase 0.22 PP_0360 Molybdate transport regulator low > 96
Pectobacterium carotovorum WPP14 0.81 HER17_RS20970 FMN-dependent L-lactate dehydrogenase LldD 0.64 HER17_RS14755 molybdenum-dependent transcriptional regulator low > 75
Pseudomonas sp. S08-1 0.80 OH686_17010 L-lactate dehydrogenase 0.23 OH686_10365 DNA-binding domain of ModE / Molybdate-binding domain of ModE low > 80
Pseudomonas fluorescens SBW25 0.73 PFLU_RS21125 FMN-dependent L-lactate dehydrogenase LldD 0.25 PFLU_RS27660 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS21125 FMN-dependent L-lactate dehydrogenase LldD 0.25 PFLU_RS27660 LysR family transcriptional regulator low > 109
Pseudomonas simiae WCS417 0.73 PS417_19130 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) 0.25 PS417_26015 ModE family transcriptional regulator low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.70 Psyr_0908 FMN-dependent alpha-hydroxy acid dehydrogenase 0.26 Psyr_4689 Helix-turn-helix, Fis-type:Molybdenum-binding protein, N-terminal:Molybdenum-pterin binding protein low > 86
Pseudomonas syringae pv. syringae B728a 0.70 Psyr_0908 FMN-dependent alpha-hydroxy acid dehydrogenase 0.26 Psyr_4689 Helix-turn-helix, Fis-type:Molybdenum-binding protein, N-terminal:Molybdenum-pterin binding protein low > 86
Caulobacter crescentus NA1000 0.61 CCNA_01209 L-lactate dehydrogenase 0.17 CCNA_00330 molybdenum-pterin binding protein mopB low > 66
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_01209 L-lactate dehydrogenase 0.17 CCNA_00330 molybdenum-pterin binding protein mopB low > 67
Rhodopseudomonas palustris CGA009 0.44 TX73_022385 alpha-hydroxy acid oxidase 0.24 TX73_024510 TOBE domain-containing protein low > 86
Ralstonia solanacearum PSI07 0.43 RPSI07_RS14000 alpha-hydroxy-acid oxidizing protein 0.22 RPSI07_RS05300 molybdenum-dependent transcriptional regulator low > 81
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS12985 L-lactate dehydrogenase 0.20 HSERO_RS14405 molybdenum transport protein ModE low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF2105 L-lactate dehydrogenase (EC 1.1.2.3) 0.28 GFF4672 DNA-binding domain of ModE / Molybdate-binding domain of ModE low > 90
Acidovorax sp. GW101-3H11 0.40 Ac3H11_1623 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) 0.12 Ac3H11_3587 DNA-binding domain of ModE / Molybdate-binding domain of ModE low > 79
Paraburkholderia graminis OAS925 0.31 ABIE53_005317 (S)-mandelate dehydrogenase 0.20 ABIE53_004836 molybdate transport system regulatory protein low > 113
Azospirillum brasilense Sp245 0.27 AZOBR_RS27055 L-lactate dehydrogenase 0.23 AZOBR_RS21350 molybdenum-pterin-binding protein low > 97
Dechlorosoma suillum PS 0.25 Dsui_1668 alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase 0.29 Dsui_0561 ModE molybdate transport repressor domain/molybdenum-pterin binding domain protein low > 51
Burkholderia phytofirmans PsJN 0.24 BPHYT_RS31690 hypothetical protein 0.22 BPHYT_RS33700 ModE family transcriptional regulator low > 109
Magnetospirillum magneticum AMB-1 0.23 AMB_RS22540 alpha-hydroxy-acid oxidizing protein 0.21 AMB_RS14845 molybdenum-dependent transcriptional regulator low > 64

Not shown: 20 genomes with orthologs for GFF409 only; 21 genomes with orthologs for GFF655 only