Conservation of cofitness between ECD_03708 and ECD_00003 in Escherichia coli BL21

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_00003 homoserine kinase 0.96 10
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.00 ECOLIN_RS00015 homoserine kinase low > 55
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 1.00 b0003 thrB homoserine kinase (NCBI) 0.66 31
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 EFB2_04040 Homoserine kinase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_03657 Homoserine kinase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NOLOHH_03435 thrB homoserine kinase 0.82 53
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 BNILDI_08165 thrB homoserine kinase 0.98 30
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 HEPCGN_09110 thrB homoserine kinase 0.83 75
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 KEDOAH_17050 thrB homoserine kinase — —
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 MCAODC_01620 thrB homoserine kinase 0.82 54
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 OKFHMN_11105 thrB homoserine kinase 0.99 11
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 JDDGAC_14700 thrB homoserine kinase low > 86
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NIAGMN_08955 thrB homoserine kinase — —
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.92 EX28DRAFT_3615 homoserine kinase (EC 2.7.1.39) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.93 GFF1079 Homoserine kinase (EC 2.7.1.39) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 BWI76_RS04250 homoserine kinase 0.25 73
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.91 MPMX20_00711 Homoserine kinase 0.29 71
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 HER17_RS02800 homoserine kinase low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 DDA3937_RS18410 homoserine kinase low > 74
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 DZA65_RS19480 homoserine kinase low > 75
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 HGI48_RS18340 homoserine kinase 0.78 56
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.77 LU632_RS02615 thrB homoserine kinase low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.80 IAI46_03035 homoserine kinase 0.82 7
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 EX31_RS03940 homoserine kinase low > 89
Pantoea sp. MT58 0.83 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 IAI47_16210 homoserine kinase low > 76
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.72 CSW01_11970 homoserine kinase low > 62
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.53 Shew_1080 homoserine kinase (RefSeq) 0.41 30
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.51 Shewana3_1140 homoserine kinase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.52 SO3414 thrB homoserine kinase (NCBI ptt file) 0.92 37
Mucilaginibacter yixingensis YX-36 DSM 26809 0.53 ABZR88_RS18615 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.23 ABZR88_RS18955 homoserine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.53 CA265_RS21095 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.22 CA265_RS23470 homoserine kinase (EC 2.7.1.39) (from data) low > 88
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.52 Sama_0906 homoserine kinase (RefSeq) 0.96 21
Echinicola vietnamensis KMM 6221, DSM 17526 0.51 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.22 Echvi_2001 homoserine kinase (EC 2.7.1.39) (from data) low > 79
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.15 ABZR86_RS15980 homoserine kinase (EC 2.7.1.39) (from data) low > 74
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.19 LRK54_RS10360 homoserine kinase low > 59
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.18 LRK55_RS10000 homoserine kinase — —

Not shown: 32 genomes with orthologs for ECD_03708 only; 7 genomes with orthologs for ECD_00003 only