| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_07980 | | NAD(P)-dependent oxidoreductase | 1.0 | CSW01_09635 | | sigma-54-dependent Fis family transcriptional regulator | 0.59 | 1 |
| Pseudomonas syringae pv. syringae B728a | 0.53 | Psyr_0904 | | Short-chain dehydrogenase/reductase SDR | 0.50 | Psyr_3913 | | Helix-turn-helix, Fis-type | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.53 | Psyr_0904 | | Short-chain dehydrogenase/reductase SDR | 0.50 | Psyr_3913 | | Helix-turn-helix, Fis-type | low | > 86 |
| Paraburkholderia graminis OAS925 | 0.51 | ABIE53_002129 | | meso-butanediol dehydrogenase/(S,S)-butanediol dehydrogenase/diacetyl reductase | 0.51 | ABIE53_000648 | | two-component system C4-dicarboxylate transport response regulator DctD | low | > 113 |
| Herbaspirillum seropedicae SmR1 | 0.51 | HSERO_RS12375 | | 3-oxoacyl-ACP reductase | 0.47 | HSERO_RS16810 | | Fis family transcriptional regulator | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.46 | QEN71_RS33455 | | SDR family NAD(P)-dependent oxidoreductase | 0.49 | QEN71_RS01375 | | sigma-54 dependent transcriptional regulator | low | > 153 |
| Rhodopseudomonas palustris CGA009 | 0.41 | TX73_000560 | | SDR family NAD(P)-dependent oxidoreductase | 0.31 | TX73_013430 | | sigma-54 dependent transcriptional regulator | — | — |
| Sinorhizobium meliloti 1021 | 0.34 | SMa0329 | | short chain alcohol dehydrogenase-related dehydrogenase | 0.50 | SM_b20613 | | C4-dicarboxylate transport transcriptional regulator | low | > 103 |
| Rhizobium sp. OAE497 | 0.32 | ABIE40_RS29645 | | SDR family oxidoreductase | 0.49 | ABIE40_RS15425 | | sigma-54 dependent transcriptional regulator | low | > 107 |
| Sphingobium sp. HT1-2 | 0.32 | GFF1478 | | Oxidoreductase, short-chain dehydrogenase/reductase family | 0.33 | GFF159 | | hypothetical protein | low | > 95 |
| Dinoroseobacter shibae DFL-12 | 0.31 | Dshi_0620 | | short-chain dehydrogenase/reductase SDR (RefSeq) | 0.47 | Dshi_1196 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | low | > 64 |
| Pseudomonas fluorescens GW456-L13 | 0.31 | PfGW456L13_2522 | | 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) | 0.50 | PfGW456L13_4775 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | low | > 87 |
| Pseudomonas putida KT2440 | 0.30 | PP_1946 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.50 | PP_0263 | | C4-dicarboxylate transport transcriptional regulatory protein | low | > 96 |
| Pseudomonas fluorescens FW300-N2E2 | 0.30 | Pf6N2E2_1004 | | 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) | 0.49 | Pf6N2E2_5565 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | low | > 103 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.30 | Echvi_2940 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | 0.34 | Echvi_0196 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | low | > 79 |
| Variovorax sp. SCN45 | 0.29 | GFF5685 | | Gluconate 5-dehydrogenase (EC 1.1.1.69) | 0.49 | GFF1691 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | low | > 127 |
| Variovorax sp. OAS795 | 0.29 | ABID97_RS22500 | | SDR family oxidoreductase | 0.50 | ABID97_RS26605 | | sigma-54 dependent transcriptional regulator | low | > 91 |
| Azospirillum brasilense Sp245 | 0.29 | AZOBR_RS28175 | | short-chain dehydrogenase | 0.55 | AZOBR_RS21130 | | Fis family transcriptional regulator | low | > 97 |
| Pseudomonas stutzeri RCH2 | 0.29 | Psest_1716 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | 0.49 | Psest_4132 | | alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) | low | > 67 |
| Pseudomonas sp. DMC3 | 0.29 | GFF1110 | | Cyclic-di-GMP-binding biofilm dispersal mediator protein | 0.50 | GFF5115 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | low | > 89 |
| Azospirillum sp. SherDot2 | 0.29 | MPMX19_03281 | | 3-oxoacyl-[acyl-carrier-protein] reductase FabG | 0.54 | MPMX19_04251 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | low | > 112 |
| Phocaeicola dorei CL03T12C01 | 0.29 | ABI39_RS19260 | | SDR family oxidoreductase | 0.32 | ABI39_RS16590 | | sigma-54-dependent Fis family transcriptional regulator | low | > 72 |
| Bosea sp. OAE506 | 0.29 | ABIE41_RS11675 | | SDR family oxidoreductase | 0.32 | ABIE41_RS16775 | | sigma-54 dependent transcriptional regulator | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.28 | PFLU_RS22960 | | SDR family oxidoreductase | 0.50 | PFLU_RS01400 | | sigma-54-dependent Fis family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.28 | PFLU_RS22960 | | SDR family oxidoreductase | 0.50 | PFLU_RS01400 | | sigma-54-dependent Fis family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens FW300-N2C3 | 0.28 | AO356_23595 | | short-chain dehydrogenase | 0.49 | AO356_18205 | | Fis family transcriptional regulator | low | > 104 |
| Pseudomonas lactucae CFBP13502 | 0.28 | GEMAOFIL_01942 | | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase | 0.49 | GEMAOFIL_00486 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.28 | Pf1N1B4_4153 | | Glucose 1-dehydrogenase (EC 1.1.1.47) | 0.50 | Pf1N1B4_776 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | low | > 87 |
| Pseudomonas sp. RS175 | 0.28 | PFR28_01507 | | Dihydroanticapsin 7-dehydrogenase | 0.49 | PFR28_03376 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | low | > 88 |
| Pseudomonas simiae WCS417 | 0.28 | PS417_21340 | | short-chain dehydrogenase | 0.50 | PS417_01305 | | Fis family transcriptional regulator | low | > 88 |
| Pseudomonas orientalis W4I3 | 0.27 | QF045_RS23425 | | SDR family oxidoreductase | 0.49 | QF045_RS04425 | | sigma-54 dependent transcriptional regulator | low | > 93 |
| Pseudomonas aeruginosa PUPa3 | 0.27 | DQ20_RS54005 | | SDR family oxidoreductase | 0.50 | DQ20_RS50420 | dctD;inference=COORDINATES | two-component system response regulator DctD | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.26 | DY961_RS19905 | | SDR family oxidoreductase | 0.50 | DY961_RS11680 | dctD;inference=COORDINATES | two-component system response regulator DctD | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.26 | IKLFDK_07915 | | SDR family oxidoreductase | 0.50 | IKLFDK_27655 | | two-component system response regulator DctD | low | > 98 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.24 | A4249_RS13930 | | SDR family oxidoreductase | 0.46 | A4249_RS04415 | | sigma-54 dependent transcriptional regulator | low | > 48 |
Not shown: 12 genomes with orthologs for CSW01_07980 only; 38 genomes with orthologs for CSW01_09635 only