Conservation of cofitness between BWI76_RS02510 and BWI76_RS20910 in Klebsiella michiganensis M5al

34 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS02510 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 1.0 BWI76_RS20910 glycine cleavage system transcriptional repressor 0.25 13
Enterobacter asburiae PDN3 0.80 EX28DRAFT_3364 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.82 EX28DRAFT_0181 Glycine cleavage system regulatory protein low > 76
Escherichia coli Nissle 1917 0.79 ECOLIN_RS24205 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 ECOLIN_RS14150 glycine cleavage system transcriptional repressor low > 55
Enterobacter sp. TBS_079 0.79 MPMX20_00448 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.83 MPMX20_03341 Glycine cleavage system transcriptional repressor low > 85
Escherichia coli BW25113 0.79 b4167 yjeF predicted carbohydrate kinase (NCBI) 0.84 b2479 gcvR transcriptional regulation of gcv operon (VIMSS) 0.28 26
Escherichia coli BL21 0.79 ECD_04034 bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase 0.84 ECD_02371 transcriptional repressor, regulatory protein accessory to GcvA 0.46 20
Escherichia coli ECRC100 0.78 OKFHMN_12280 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 OKFHMN_21910 gcvR glycine cleavage system transcriptional repressor low > 80
Escherichia coli ECRC99 0.78 KEDOAH_15875 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 KEDOAH_06310 gcvR glycine cleavage system transcriptional repressor — —
Escherichia coli ECRC101 0.78 MCAODC_02795 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 MCAODC_12440 gcvR glycine cleavage system transcriptional repressor 0.39 53
Escherichia coli ECRC102 0.78 NIAGMN_10130 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 NIAGMN_19680 gcvR glycine cleavage system transcriptional repressor — —
Escherichia coli ECRC98 0.78 JDDGAC_15920 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 JDDGAC_25855 gcvR glycine cleavage system transcriptional repressor low > 86
Escherichia fergusonii Becca 0.78 EFB2_04368 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.84 EFB2_01407 Glycine cleavage system transcriptional repressor low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.78 OHPLBJKB_03875 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.84 OHPLBJKB_01250 Glycine cleavage system transcriptional repressor low > 73
Escherichia coli ECRC62 0.78 BNILDI_06945 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 BNILDI_12380 gcvR glycine cleavage system transcriptional repressor low > 75
Escherichia coli ECOR27 0.78 NOLOHH_04545 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 NOLOHH_13570 gcvR glycine cleavage system transcriptional repressor low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF820 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.85 GFF2179 Glycine cleavage system transcriptional antiactivator GcvR low > 78
Escherichia coli ECOR38 0.78 HEPCGN_10510 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 HEPCGN_21080 gcvR glycine cleavage system transcriptional repressor low > 87
Erwinia tracheiphila SCR3 0.67 LU632_RS02030 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.73 LU632_RS08320 glycine cleavage system transcriptional repressor low > 74
Rahnella sp. WP5 0.65 EX31_RS08845 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.70 EX31_RS22735 glycine cleavage system transcriptional repressor low > 89
Dickeya dianthicola 67-19 0.64 HGI48_RS18570 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.72 HGI48_RS06105 glycine cleavage system transcriptional repressor low > 71
Dickeya dianthicola ME23 0.63 DZA65_RS19705 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.72 DZA65_RS06455 glycine cleavage system transcriptional repressor low > 75
Serratia liquefaciens MT49 0.63 IAI46_01600 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.76 IAI46_18785 glycine cleavage system transcriptional repressor low > 86
Pectobacterium carotovorum WPP14 0.62 HER17_RS02560 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.70 HER17_RS15420 glycine cleavage system transcriptional repressor low > 75
Dickeya dadantii 3937 0.60 DDA3937_RS18635 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.72 DDA3937_RS06060 glycine cleavage system transcriptional repressor low > 74
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_14940 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.36 CSW01_10760 glycine cleavage system transcriptional regulator low > 62
Alteromonas macleodii MIT1002 0.38 MIT1002_03793 Nicotinamide nucleotide repair protein 0.22 MIT1002_02208 Gcv operon repressor low > 70
Shewanella amazonensis SB2B 0.36 Sama_3030 YjeF protein (RefSeq) 0.30 Sama_1909 glycine cleavage system transcriptional repressor, putative (RefSeq) low > 62
Shewanella sp. ANA-3 0.36 Shewana3_0592 carbohydrate kinase, YjeF related protein (RefSeq) 0.29 Shewana3_1655 glycine cleavage system transcriptional repressor, putative (RefSeq) low > 73
Shewanella oneidensis MR-1 0.36 SO0598 yjeF yjeF protein (NCBI ptt file) 0.30 SO1878 glycine cleavage system transcriptional repressor, putative (NCBI ptt file) low > 76
Rhodanobacter denitrificans FW104-10B01 0.34 LRK54_RS15135 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.16 LRK54_RS15080 glycine cleavage system protein R low > 59
Shewanella loihica PV-4 0.34 Shew_0561 carbohydrate kinase, YjeF-related protein (RefSeq) 0.28 Shew_1847 amino acid-binding ACT domain-containing protein (RefSeq) — —
Rhodanobacter denitrificans MT42 0.34 LRK55_RS14850 NAD(P)H-hydrate dehydratase 0.16 LRK55_RS14795 glycine cleavage system protein R low > 63
Lysobacter sp. OAE881 0.34 ABIE51_RS08050 NAD(P)H-hydrate dehydratase 0.17 ABIE51_RS07990 glycine cleavage system protein R low > 62
Dyella japonica UNC79MFTsu3.2 0.33 ABZR86_RS00840 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.17 ABZR86_RS00780 glycine cleavage system protein R low > 74
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.2253.1 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.16 Xcc-8004.3086.1 Glycine cleavage system transcriptional antiactivator GcvR — —

Not shown: 60 genomes with orthologs for BWI76_RS02510 only; 1 genomes with orthologs for BWI76_RS20910 only