Conservation of cofitness between BWI76_RS04245 and BWI76_RS00850 in Klebsiella michiganensis M5al

39 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 1.0 BWI76_RS00850 acetylglutamate kinase 0.94 9
Escherichia coli BW25113 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.90 b3959 argB acetylglutamate kinase (RefSeq) 0.87 49
Escherichia coli ECOR38 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 HEPCGN_12225 acetylglutamate kinase 0.97 11
Escherichia coli ECRC101 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 MCAODC_04080 acetylglutamate kinase 0.90 8
Escherichia coli ECRC98 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 JDDGAC_17205 acetylglutamate kinase 0.77 70
Escherichia fergusonii Becca 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.89 EFB2_04655 Acetylglutamate kinase low > 86
Escherichia coli ECRC99 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 KEDOAH_14580 acetylglutamate kinase — —
Escherichia coli ECRC102 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 NIAGMN_11330 acetylglutamate kinase — —
Escherichia coli ECRC100 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 OKFHMN_13580 acetylglutamate kinase 0.98 16
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.90 OHPLBJKB_04091 Acetylglutamate kinase low > 73
Escherichia coli ECOR27 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 NOLOHH_05725 acetylglutamate kinase 0.96 11
Escherichia coli BL21 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.90 ECD_03844 acetylglutamate kinase 0.90 26
Escherichia coli ECRC62 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 BNILDI_05800 acetylglutamate kinase 0.99 4
Escherichia coli Nissle 1917 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.89 ECOLIN_RS22850 acetylglutamate kinase 0.49 34
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.87 GFF2345 Acetylglutamate kinase (EC 2.7.2.8) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.90 MPMX20_04521 Acetylglutamate kinase 0.88 38
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.91 EX28DRAFT_4421 N-acetylglutamate kinase (EC 2.7.2.8) 0.79 32
Rahnella sp. WP5 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.78 EX31_RS14185 acetylglutamate kinase 0.97 27
Pantoea sp. MT58 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 IAI47_00910 acetylglutamate kinase low > 76
Serratia liquefaciens MT49 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 IAI46_24510 acetylglutamate kinase 0.88 8
Pectobacterium carotovorum WPP14 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 HER17_RS20625 acetylglutamate kinase low > 75
Erwinia tracheiphila SCR3 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.81 LU632_RS19610 argB acetylglutamate kinase 0.70 32
Dickeya dadantii 3937 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 DDA3937_RS20345 acetylglutamate kinase 0.82 42
Dickeya dianthicola 67-19 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 HGI48_RS00880 acetylglutamate kinase 0.76 56
Dickeya dianthicola ME23 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 DZA65_RS00940 acetylglutamate kinase 0.78 41
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I 0.56 CSW01_13375 acetylglutamate kinase low > 62
Shewanella loihica PV-4 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.47 Shew_0203 acetylglutamate kinase (RefSeq) 0.99 9
Shewanella oneidensis MR-1 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.43 SO0276 argB acetylglutamate kinase (NCBI ptt file) 0.85 23
Shewanella sp. ANA-3 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.43 Shewana3_3904 acetylglutamate kinase (RefSeq) 0.85 70
Alteromonas macleodii MIT1002 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.37 MIT1002_00470 Acetylglutamate kinase 0.97 28
Shewanella amazonensis SB2B 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.41 Sama_0257 acetylglutamate kinase (RefSeq) 0.90 39
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.15 Echvi_3850 acetylglutamate kinase 0.95 22
Mucilaginibacter yixingensis YX-36 DSM 26809 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I 0.21 ABZR88_RS09860 acetylglutamate kinase — —
Phocaeicola vulgatus CL09T03C04 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.18 HMPREF1058_RS12115 acetylglutamate kinase low > 67
Pedobacter sp. GW460-11-11-14-LB5 0.32 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.16 CA265_RS18510 acetylglutamate kinase — —
Phocaeicola dorei CL03T12C01 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.17 ABI39_RS04685 acetylglutamate kinase 0.82 31
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.16 HMPREF1078_RS15335 acetylglutamate kinase 0.96 26
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.17 HMPREF1181_RS02540 acetylglutamate kinase 0.98 9
Bacteroides thetaiotaomicron VPI-5482 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.17 BT3395 N-succinylglutamate kinase (EC 2.7.2.-) (from data) 0.90 9
Bacteroides ovatus ATCC 8483 0.28 BACOVA_03021 homoserine dehydrogenase 0.17 BACOVA_01910 acetylglutamate kinase 0.96 11

Not shown: 2 genomes with orthologs for BWI76_RS04245 only; 14 genomes with orthologs for BWI76_RS00850 only