Conservation of cofitness between b3962 and b1130 in Escherichia coli BW25113

42 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3962 udhA putative oxidoreductase (VIMSS) 1.0 b1130 phoP DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) 0.48 5
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04088 Soluble pyridine nucleotide transhydrogenase 1.00 OHPLBJKB_02538 Transcriptional regulatory protein PhoP low > 73
Escherichia coli ECOR38 1.00 HEPCGN_12205 sthA Si-specific NAD(P)(+) transhydrogenase 1.00 HEPCGN_24200 phoP two-component system response regulator PhoP low > 85
Escherichia coli ECRC98 1.00 JDDGAC_17185 sthA Si-specific NAD(P)(+) transhydrogenase 0.99 JDDGAC_06635 phoP two-component system response regulator PhoP — —
Escherichia coli ECRC101 1.00 MCAODC_04060 sthA Si-specific NAD(P)(+) transhydrogenase 0.99 MCAODC_22355 phoP two-component system response regulator PhoP — —
Escherichia coli ECRC99 1.00 KEDOAH_14600 sthA Si-specific NAD(P)(+) transhydrogenase 0.99 KEDOAH_24815 phoP two-component system response regulator PhoP — —
Escherichia coli ECRC62 1.00 BNILDI_05830 sthA Si-specific NAD(P)(+) transhydrogenase 1.00 BNILDI_19080 phoP two-component system response regulator PhoP — —
Escherichia coli ECOR27 1.00 NOLOHH_05695 sthA Si-specific NAD(P)(+) transhydrogenase 1.00 NOLOHH_20915 phoP two-component system response regulator PhoP — —
Escherichia coli ECRC101 1.00 OKFHMN_13560 sthA Si-specific NAD(P)(+) transhydrogenase 0.99 OKFHMN_00730 phoP two-component system response regulator PhoP — —
Escherichia fergusonii Becca 1.00 EFB2_04650 Soluble pyridine nucleotide transhydrogenase 1.00 EFB2_02845 Transcriptional regulatory protein PhoP low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS22875 Si-specific NAD(P)(+) transhydrogenase 1.00 ECOLIN_RS06610 two-component system response regulator PhoP — —
Escherichia coli ECRC102 1.00 NIAGMN_11310 sthA Si-specific NAD(P)(+) transhydrogenase 0.99 NIAGMN_24875 phoP two-component system response regulator PhoP — —
Escherichia coli BL21 1.00 ECD_03847 pyridine nucleotide transhydrogenase, soluble 1.00 ECD_01128 response regulator in two-component regulatory system with PhoQ — —
Enterobacter sp. TBS_079 0.97 MPMX20_04518 Soluble pyridine nucleotide transhydrogenase 0.95 MPMX20_01811 Transcriptional regulatory protein PhoP low > 85
Enterobacter asburiae PDN3 0.97 EX28DRAFT_4425 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes 0.96 EX28DRAFT_1800 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 76
Klebsiella michiganensis M5al 0.95 BWI76_RS00870 NAD(P)(+) transhydrogenase 0.93 BWI76_RS11280 two-component system response regulator PhoP — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2348 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) 0.95 GFF3415 Transcriptional regulatory protein PhoP low > 78
Pantoea sp. MT58 0.91 IAI47_00935 Si-specific NAD(P)(+) transhydrogenase 0.83 IAI47_11930 two-component system response regulator PhoP 0.53 26
Erwinia tracheiphila SCR3 0.90 LU632_RS19585 sthA Si-specific NAD(P)(+) transhydrogenase 0.84 LU632_RS14590 phoP two-component system response regulator PhoP low > 74
Dickeya dadantii 3937 0.87 DDA3937_RS00975 Si-specific NAD(P)(+) transhydrogenase 0.78 DDA3937_RS11500 two-component system response regulator PhoP low > 74
Dickeya dianthicola 67-19 0.87 HGI48_RS20400 Si-specific NAD(P)(+) transhydrogenase 0.78 HGI48_RS11545 two-component system response regulator PhoP low > 71
Dickeya dianthicola ME23 0.87 DZA65_RS21445 Si-specific NAD(P)(+) transhydrogenase 0.78 DZA65_RS11880 two-component system response regulator PhoP low > 75
Pectobacterium carotovorum WPP14 0.86 HER17_RS00960 Si-specific NAD(P)(+) transhydrogenase 0.81 HER17_RS11640 two-component system response regulator PhoP 0.83 41
Serratia liquefaciens MT49 0.85 IAI46_24470 Si-specific NAD(P)(+) transhydrogenase 0.87 IAI46_10395 two-component system response regulator PhoP low > 86
Rahnella sp. WP5 0.85 EX31_RS14165 Si-specific NAD(P)(+) transhydrogenase 0.85 EX31_RS24560 two-component system response regulator PhoP low > 89
Alteromonas macleodii MIT1002 0.72 MIT1002_03373 Soluble pyridine nucleotide transhydrogenase 0.43 MIT1002_01421 Transcriptional regulatory protein PhoP low > 70
Pseudomonas stutzeri RCH2 0.63 Psest_1663 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes 0.47 Psest_3883 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 67
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_1901 FAD-dependent pyridine nucleotide-disulfide oxidoreductase:Pyridine nucleotide-disulfide oxidoreductase dimerization region 0.49 Psyr_3709 Response regulator receiver:Transcriptional regulatory protein, C-terminal — —
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_1901 FAD-dependent pyridine nucleotide-disulfide oxidoreductase:Pyridine nucleotide-disulfide oxidoreductase dimerization region 0.49 Psyr_3709 Response regulator receiver:Transcriptional regulatory protein, C-terminal — —
Pseudomonas putida KT2440 0.62 PP_2151 soluble pyridine nucleotide transhydrogenase 0.51 PP_1186 two component system DNA-binding transcriptional dual regulator — —
Pseudomonas simiae WCS417 0.62 PS417_07650 pyridine nucleotide-disulfide oxidoreductase 0.51 PS417_21515 transcriptional regulator — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_4024 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) 0.50 PfGW456L13_2011 Transcriptional regulatory protein PhoP — —
Pseudomonas fluorescens SBW25-INTG 0.62 PFLU_RS07725 Si-specific NAD(P)(+) transhydrogenase 0.47 PFLU_RS23130 response regulator transcription factor low > 109
Pseudomonas fluorescens SBW25 0.62 PFLU_RS07725 Si-specific NAD(P)(+) transhydrogenase 0.47 PFLU_RS23130 response regulator transcription factor low > 109
Pseudomonas sp. RS175 0.62 PFR28_01127 Soluble pyridine nucleotide transhydrogenase 0.52 PFR28_03244 Transcriptional regulatory protein PhoP low > 88
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_02250 pyridine nucleotide-disulfide oxidoreductase 0.52 AO356_18965 transcriptional regulator 0.33 37
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_3919 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) 0.50 Pf1N1B4_3483 Transcriptional regulatory protein PhoP — —
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_00390 pyridine nucleotide-disulfide oxidoreductase 0.50 AO353_02815 transcriptional regulator — —
Pseudomonas fluorescens FW300-N2E2 0.61 Pf6N2E2_2274 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) 0.52 Pf6N2E2_5704 Transcriptional regulatory protein PhoP low > 103
Marinobacter adhaerens HP15 0.60 HP15_2245 soluble pyridine nucleotide transhydrogenase 0.37 HP15_185 two component transcriptional regulator, winged helix family — —
Agrobacterium fabrum C58 0.38 Atu1661 soluble pyridine nucleotide transhydrogenase 0.41 Atu0970 two component response regulator — —
Sinorhizobium meliloti 1021 0.36 SMc00300 soluble pyridine nucleotide transhydrogenase 0.41 SMc00458 transcriptional regulator low > 103
Rhizobium sp. OAE497 0.36 ABIE40_RS08610 Si-specific NAD(P)(+) transhydrogenase 0.40 ABIE40_RS05660 response regulator transcription factor low > 107

Not shown: 5 genomes with orthologs for b3962 only; 20 genomes with orthologs for b1130 only