Conservation of cofitness between b4235 and b0920 in Escherichia coli BW25113

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 1.0 b0920 ycbC conserved inner membrane protein (NCBI) 0.28 15
Escherichia coli ECRC99 1.00 KEDOAH_16230 pmbA metalloprotease PmbA 1.00 KEDOAH_22310 elyC envelope biogenesis factor ElyC — —
Escherichia coli ECRC102 1.00 NIAGMN_09775 pmbA metalloprotease PmbA 1.00 NIAGMN_03145 elyC envelope biogenesis factor ElyC — —
Escherichia coli ECRC62 1.00 BNILDI_07325 pmbA metalloprotease PmbA 0.99 BNILDI_20240 elyC envelope biogenesis factor ElyC — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03800 Metalloprotease PmbA 1.00 OHPLBJKB_02747 hypothetical protein low > 73
Escherichia coli ECRC101 1.00 OKFHMN_11925 pmbA metalloprotease PmbA 1.00 OKFHMN_05425 elyC envelope biogenesis factor ElyC — —
Escherichia coli ECRC101 1.00 MCAODC_02430 pmbA metalloprotease PmbA 1.00 MCAODC_24815 elyC envelope biogenesis factor ElyC — —
Escherichia coli ECOR27 1.00 NOLOHH_04185 pmbA metalloprotease PmbA 0.99 NOLOHH_21985 elyC envelope biogenesis factor ElyC low > 57
Escherichia coli ECOR38 1.00 HEPCGN_10125 pmbA metalloprotease PmbA 1.00 HEPCGN_23100 elyC envelope biogenesis factor ElyC low > 85
Escherichia coli ECRC98 1.00 JDDGAC_15565 pmbA metalloprotease PmbA 1.00 JDDGAC_09035 elyC envelope biogenesis factor ElyC — —
Escherichia coli BL21 1.00 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 1.00 ECD_00924 envelope biogenesis factor; DUF218 superfamily protein — —
Escherichia fergusonii Becca 0.99 EFB2_04298 Metalloprotease PmbA 1.00 EFB2_03144 hypothetical protein low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS24570 metalloprotease PmbA 1.00 ECOLIN_RS04870 envelope biogenesis factor ElyC — —
Enterobacter sp. TBS_079 0.97 MPMX20_00517 Metalloprotease PmbA 0.76 MPMX20_01578 hypothetical protein low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.83 GFF3677 Membrane Protein Functionally coupled to the MukBEF Chromosome Partitioning Mechanism low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.79 EX28DRAFT_2016 Uncharacterized conserved protein low > 76
Klebsiella michiganensis M5al 0.94 BWI76_RS02850 metalloprotease PmbA 0.70 BWI76_RS09825 envelope biogenesis factor ElyC low > 92
Serratia liquefaciens MT49 0.86 IAI46_22575 metalloprotease PmbA 0.53 IAI46_08710 envelope biogenesis factor ElyC low > 86
Rahnella sp. WP5 0.85 EX31_RS12320 metalloprotease PmbA 0.57 EX31_RS18185 envelope biogenesis factor ElyC low > 89
Pectobacterium carotovorum WPP14 0.84 HER17_RS20090 metalloprotease PmbA 0.61 HER17_RS12070 envelope biogenesis factor ElyC low > 75
Pantoea sp. MT58 0.84 IAI47_02765 metalloprotease PmbA 0.55 IAI47_12805 envelope biogenesis factor ElyC low > 76
Erwinia tracheiphila SCR3 0.81 LU632_RS02145 pmbA metalloprotease PmbA 0.65 LU632_RS09860 elyC envelope biogenesis factor ElyC low > 74
Dickeya dadantii 3937 0.81 DDA3937_RS01500 metalloprotease PmbA 0.56 DDA3937_RS09870 envelope biogenesis factor ElyC low > 74
Dickeya dianthicola ME23 0.81 DZA65_RS01480 metalloprotease PmbA 0.57 DZA65_RS10215 envelope biogenesis factor ElyC low > 75
Dickeya dianthicola 67-19 0.81 HGI48_RS01415 metalloprotease PmbA 0.57 HGI48_RS09880 envelope biogenesis factor ElyC low > 71
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_12845 metalloprotease PmbA 0.38 CSW01_08640 envelope biogenesis factor ElyC low > 62
Shewanella sp. ANA-3 0.59 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.20 Shewana3_2789 hypothetical protein (RefSeq) low > 73
Shewanella loihica PV-4 0.57 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.24 Shew_1429 hypothetical protein (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.54 MIT1002_00230 peptidase PmbA 0.14 MIT1002_02841 hypothetical protein low > 70
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS09265 peptidase C69 0.14 HSERO_RS13720 hypothetical protein 0.29 48
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS21700 metalloprotease PmbA 0.11 ABZR86_RS18570 YdcF family protein low > 74
Dechlorosoma suillum PS 0.44 Dsui_1234 putative Zn-dependent protease-like protein 0.13 Dsui_2924 hypothetical protein low > 51
Acidovorax sp. GW101-3H11 0.44 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.12 Ac3H11_4852 Protein of unknown function DUF218 low > 79
Castellaniella sp019104865 MT123 0.42 ABCV34_RS10610 metalloprotease PmbA 0.13 ABCV34_RS02460 YdcF family protein — —
Azospirillum sp. SherDot2 0.34 MPMX19_01886 Metalloprotease PmbA 0.11 MPMX19_01463 hypothetical protein low > 112
Magnetospirillum magneticum AMB-1 0.29 AMB_RS22120 TldD/PmbA family protein 0.13 AMB_RS12330 YdcF family protein low > 64
Rhodopseudomonas palustris CGA009 0.29 TX73_005930 TldD/PmbA family protein 0.16 TX73_016340 YdcF family protein low > 86
Rhizobium sp. OAE497 0.26 ABIE40_RS03780 TldD/PmbA family protein 0.13 ABIE40_RS00405 YdcF family protein low > 107

Not shown: 51 genomes with orthologs for b4235 only; 3 genomes with orthologs for b0920 only