Conservation of cofitness between b3960 and b0002 in Escherichia coli BW25113

39 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3960 argH argininosuccinate lyase (NCBI) 1.0 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.96 3
Escherichia coli BL21 1.00 ECD_03845 argininosuccinate lyase 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.91 1
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04090 Argininosuccinate lyase 0.99 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli ECOR38 1.00 HEPCGN_12220 argH argininosuccinate lyase 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS22855 argininosuccinate lyase 1.00 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 52
Escherichia fergusonii Becca 0.99 EFB2_04654 Argininosuccinate lyase 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli ECRC62 0.99 BNILDI_05805 argH argininosuccinate lyase 0.99 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECOR27 0.99 NOLOHH_05720 argH argininosuccinate lyase 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 57
Escherichia coli ECRC98 0.99 JDDGAC_17200 argH argininosuccinate lyase 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC99 0.99 KEDOAH_14585 argH argininosuccinate lyase 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 0.99 MCAODC_04075 argH argininosuccinate lyase 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 0.99 OKFHMN_13575 argH argininosuccinate lyase 1.00 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC102 0.99 NIAGMN_11325 argH argininosuccinate lyase 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Klebsiella michiganensis M5al 0.96 BWI76_RS00855 argininosuccinate lyase 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 8
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF2346 Argininosuccinate lyase (EC 4.3.2.1) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_4422 argininosuccinate lyase 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.88 11
Enterobacter sp. TBS_079 0.93 MPMX20_04520 Argininosuccinate lyase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.90 22
Serratia liquefaciens MT49 0.88 IAI46_24500 argininosuccinate lyase 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 8
Rahnella sp. WP5 0.88 EX31_RS14180 argininosuccinate lyase 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 18
Pantoea sp. MT58 0.88 IAI47_00920 argininosuccinate lyase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 21
Erwinia tracheiphila SCR3 0.88 LU632_RS19600 argH argininosuccinate lyase 0.82 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.75 31
Dickeya dadantii 3937 0.86 DDA3937_RS20340 argininosuccinate lyase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 22
Pectobacterium carotovorum WPP14 0.86 HER17_RS20620 argininosuccinate lyase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I low > 75
Dickeya dianthicola 67-19 0.84 HGI48_RS00885 argininosuccinate lyase 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 21
Dickeya dianthicola ME23 0.84 DZA65_RS00945 argininosuccinate lyase 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.68 39
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_13360 argininosuccinate lyase 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella amazonensis SB2B 0.65 Sama_0260 argininosuccinate lyase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.92 42
Shewanella sp. ANA-3 0.63 Shewana3_3901 argininosuccinate lyase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.84 51
Shewanella oneidensis MR-1 0.63 SO0279 argH argininosuccinate lyase (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.86 65
Shewanella loihica PV-4 0.62 Shew_0206 argininosuccinate lyase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.98 13
Alteromonas macleodii MIT1002 0.57 MIT1002_00467 Argininosuccinate lyase 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.99 4
Pedobacter sp. GW460-11-11-14-LB5 0.26 CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) (from data) 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.95 8
Echinicola vietnamensis KMM 6221, DSM 17526 0.25 Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) (from data) 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.95 5
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS07095 argininosuccinate lyase 0.31 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 7
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS09585 argininosuccinate lyase 0.31 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.71 19
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS12070 argininosuccinate lyase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Bacteroides ovatus ATCC 8483 0.24 BACOVA_03551 argininosuccinate lyase 0.27 BACOVA_03021 homoserine dehydrogenase 0.95 10
Bacteroides stercoris CC31F 0.24 HMPREF1181_RS03410 argininosuccinate lyase 0.27 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.99 7
Lysobacter sp. OAE881 0.22 ABIE51_RS13380 argininosuccinate lyase 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 27
Xanthomonas campestris pv. campestris strain 8004 0.19 Xcc-8004.2323.1 Argininosuccinate lyase (EC 4.3.2.1) 0.34 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.94 9

Not shown: 61 genomes with orthologs for b3960 only; 2 genomes with orthologs for b0002 only