Conservation of cofitness between GFF2198 and GFF233 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF2198 NADP-dependent malic enzyme (EC 1.1.1.40) 1.0 GFF233 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly 0.59 14
Escherichia coli ECRC102 0.95 NIAGMN_19775 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 NIAGMN_12195 cyaY iron donor protein CyaY — —
Escherichia coli ECRC101 0.95 OKFHMN_22005 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 OKFHMN_14440 cyaY iron donor protein CyaY — —
Escherichia coli ECRC98 0.95 JDDGAC_25950 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 JDDGAC_18065 cyaY iron donor protein CyaY — —
Escherichia coli ECRC101 0.95 MCAODC_12535 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 MCAODC_04945 cyaY iron donor protein CyaY — —
Escherichia fergusonii Becca 0.95 EFB2_01425 NADP-dependent malic enzyme 0.85 EFB2_04831 Iron-sulfur cluster assembly protein CyaY low > 86
Escherichia coli ECOR38 0.95 HEPCGN_21175 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.86 HEPCGN_13160 cyaY iron donor protein CyaY low > 85
Escherichia coli ECRC62 0.95 BNILDI_12495 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.87 BNILDI_04950 cyaY iron donor protein CyaY — —
Escherichia coli ECOR27 0.95 NOLOHH_13685 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.87 NOLOHH_06585 cyaY iron donor protein CyaY low > 57
Escherichia coli Nissle 1917 0.95 ECOLIN_RS14055 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 ECOLIN_RS21845 iron donor protein CyaY low > 52
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0198 Malic enzyme 0.81 EX28DRAFT_4476 iron donor protein CyaY — —
Escherichia coli BW25113 0.95 b2463 maeB malic enzyme (NCBI) 0.87 b3807 cyaY frataxin-like protein (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_01268 NADP-dependent malic enzyme 0.96 OHPLBJKB_04246 Iron-sulfur cluster assembly protein CyaY low > 73
Escherichia coli ECRC99 0.95 KEDOAH_06215 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 KEDOAH_13710 cyaY iron donor protein CyaY — —
Escherichia coli BL21 0.95 ECD_02354 malic enzyme: putative oxidoreductase/phosphotransacetylase 0.86 ECD_03682 iron-dependent inhibitor of iron-sulfur cluster formation; frataxin; iron-binding and oxidizing protein — —
Enterobacter sp. TBS_079 0.94 MPMX20_03324 NADP-dependent malic enzyme 0.82 MPMX20_04468 Iron-sulfur cluster assembly protein CyaY low > 85
Klebsiella michiganensis M5al 0.94 BWI76_RS20830 bifunctional malic enzyme oxidoreductase/phosphotransacetylase 0.86 BWI76_RS01190 iron donor protein CyaY low > 92
Serratia liquefaciens MT49 0.87 IAI46_18585 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.64 IAI46_00705 iron donor protein CyaY low > 86
Pectobacterium carotovorum WPP14 0.87 HER17_RS17280 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.73 HER17_RS01330 iron donor protein CyaY low > 75
Dickeya dadantii 3937 0.86 DDA3937_RS04355 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.73 DDA3937_RS19910 iron donor protein CyaY low > 74
Dickeya dianthicola ME23 0.85 DZA65_RS04265 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.72 DZA65_RS21110 iron donor protein CyaY low > 75
Dickeya dianthicola 67-19 0.84 HGI48_RS04345 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.73 HGI48_RS20065 iron donor protein CyaY — —
Dechlorosoma suillum PS 0.63 Dsui_0543 malic enzyme 0.35 Dsui_1184 iron donor protein CyaY — —
Paraburkholderia graminis OAS925 0.63 ABIE53_000015 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) 0.45 ABIE53_003747 CyaY protein — —
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_05846 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) 0.43 H281DRAFT_05608 CyaY protein — —
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS18310 malic enzyme 0.47 BPHYT_RS17920 protein CyaY low > 109
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS28455 NADP-dependent malic enzyme 0.49 QEN71_RS28070 iron donor protein CyaY low > 153
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS16825 NADP-dependent malic enzyme oxidoreductase 0.39 HSERO_RS00945 frataxin — —
Ralstonia solanacearum UW163 0.62 UW163_RS10465 NADP-dependent malic enzyme 0.37 UW163_RS06635 iron donor protein CyaY — —
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS03260 NADP-dependent malic enzyme 0.37 RALBFv3_RS06980 iron donor protein CyaY low > 76
Ralstonia solanacearum GMI1000 0.62 RS_RS10650 NADP-dependent malic enzyme 0.37 RS_RS14920 iron donor protein CyaY low > 80
Ralstonia solanacearum PSI07 0.62 RPSI07_RS14050 NADP-dependent malic enzyme 0.38 RPSI07_RS10260 iron donor protein CyaY low > 81
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS05210 malic enzyme 0.33 RR42_RS19045 frataxin low > 128
Variovorax sp. OAS795 0.61 ABID97_RS22340 NADP-dependent malic enzyme 0.43 ABID97_RS23295 iron donor protein CyaY — —
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS01565 NADP-dependent malic enzyme 0.37 ABZR87_RS02630 iron donor protein CyaY low > 80
Variovorax sp. SCN45 0.60 GFF1796 NADP-dependent malic enzyme (EC 1.1.1.40) 0.41 GFF5317 Frataxin homolog CyaY, facilitates Fe-S cluster assembly, interacts with IscS low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF3306 NADP-dependent malic enzyme (EC 1.1.1.40) 0.41 GFF1339 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly low > 90
Magnetospirillum magneticum AMB-1 0.60 AMB_RS03695 NADP-dependent malic enzyme 0.26 AMB_RS15295 iron donor protein CyaY low > 64
Acidovorax sp. GW101-3H11 0.59 Ac3H11_1079 NADP-dependent malic enzyme (EC 1.1.1.40) 0.41 Ac3H11_4699 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly — —

Not shown: 33 genomes with orthologs for GFF2198 only; 19 genomes with orthologs for GFF233 only