Conservation of cofitness between BWI76_RS12790 and BWI76_RS04225 in Klebsiella michiganensis M5al

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS12790 lactate dehydrogenase 1.0 BWI76_RS04225 cell envelope integrity protein CreD 0.20 11
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2638 D-lactate dehydrogenase (EC 1.1.1.28) 0.64 GFF1068 Inner membrane protein CreD low > 78
Enterobacter sp. TBS_079 0.92 MPMX20_02132 D-lactate dehydrogenase 0.60 MPMX20_00707 Inner membrane protein CreD low > 85
Enterobacter asburiae PDN3 0.92 EX28DRAFT_1435 Lactate dehydrogenase and related dehydrogenases 0.63 EX28DRAFT_3610 Inner membrane protein involved in colicin E2 resistance low > 76
Escherichia coli ECOR27 0.91 NOLOHH_19530 ldhA D-lactate dehydrogenase 0.64 NOLOHH_03460 creD cell envelope integrity protein CreD low > 75
Escherichia coli BW25113 0.91 b1380 ldhA D-lactate dehydrogenase (NCBI) 0.64 b4400 creD inner membrane protein (NCBI) low > 76
Escherichia coli ECOR38 0.91 HEPCGN_26050 ldhA D-lactate dehydrogenase 0.64 HEPCGN_09135 creD cell envelope integrity protein CreD low > 87
Escherichia fergusonii Becca 0.91 EFB2_02576 D-lactate dehydrogenase 0.63 EFB2_04044 Inner membrane protein CreD low > 86
Escherichia coli ECRC102 0.91 NIAGMN_25930 ldhA D-lactate dehydrogenase 0.64 NIAGMN_08980 creD cell envelope integrity protein CreD — —
Escherichia coli ECRC101 0.91 MCAODC_16140 ldhA D-lactate dehydrogenase 0.64 MCAODC_01645 creD cell envelope integrity protein CreD low > 87
Escherichia coli ECRC99 0.91 KEDOAH_26640 ldhA D-lactate dehydrogenase 0.64 KEDOAH_17025 creD cell envelope integrity protein CreD — —
Escherichia coli BL21 0.91 ECD_01352 fermentative D-lactate dehydrogenase, NAD-dependent 0.64 ECD_04276 inner membrane protein low > 61
Escherichia coli ECRC98 0.91 JDDGAC_04285 ldhA D-lactate dehydrogenase 0.64 JDDGAC_14725 creD cell envelope integrity protein CreD low > 86
Escherichia coli Nissle 1917 0.91 ECOLIN_RS08110 D-lactate dehydrogenase 0.64 ECOLIN_RS25250 cell envelope integrity protein CreD low > 55
Escherichia coli ECRC100 0.91 OKFHMN_01795 ldhA D-lactate dehydrogenase 0.64 OKFHMN_11130 creD cell envelope integrity protein CreD low > 80
Escherichia coli ECRC62 0.91 BNILDI_17985 ldhA D-lactate dehydrogenase 0.64 BNILDI_08140 creD cell envelope integrity protein CreD low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.91 OHPLBJKB_02331 D-lactate dehydrogenase 0.64 OHPLBJKB_03661 Inner membrane protein CreD low > 73
Serratia liquefaciens MT49 0.82 IAI46_13355 2-hydroxyacid dehydrogenase 0.47 IAI46_20740 cell envelope integrity protein CreD low > 86
Shewanella loihica PV-4 0.67 Shew_0787 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.17 Shew_0303 hypothetical protein (RefSeq) low > 60
Shewanella oneidensis MR-1 0.64 SO0968 ldhA D-lactate dehydrogenase (NCBI ptt file) 0.17 SO4334 inner membrane protein, putative (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.64 Shewana3_3319 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.17 Shewana3_0365 hypothetical protein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.63 Sama_0612 D-lactate dehydrogenase (RefSeq) 0.16 Sama_3274 hypothetical protein (RefSeq) low > 62
Agrobacterium fabrum C58 0.51 Atu3870 D-lactate dehydrogenase 0.22 Atu1155 hypothetical protein low > 89
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_19040 hydroxyacid dehydrogenase 0.26 AO356_14045 hypothetical protein low > 104
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_02740 hydroxyacid dehydrogenase 0.27 AO353_07585 hypothetical protein low > 101
Pseudomonas sp. RS175 0.50 PFR28_03228 D-lactate dehydrogenase 0.25 PFR28_04121 Inner membrane protein CreD low > 88
Pseudomonas sp. S08-1 0.50 OH686_18940 D-lactate dehydrogenase 0.31 OH686_14840 Inner membrane protein CreD low > 80
Pseudomonas fluorescens FW300-N2E2 0.50 Pf6N2E2_5719 D-lactate dehydrogenase (EC 1.1.1.28) 0.25 Pf6N2E2_4740 Inner membrane protein CreD low > 103
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_3500 D-lactate dehydrogenase (EC 1.1.1.28) 0.26 Pf1N1B4_2468 Inner membrane protein CreD low > 87
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_2028 D-lactate dehydrogenase (EC 1.1.1.28) 0.25 PfGW456L13_1129 Inner membrane protein CreD low > 87
Pseudomonas simiae WCS417 0.49 PS417_16375 2-hydroxyacid dehydrogenase 0.26 PS417_26130 membrane protein low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.48 Echvi_3936 Lactate dehydrogenase and related dehydrogenases 0.25 Echvi_1437 Inner membrane protein involved in colicin E2 resistance low > 79
Pseudomonas fluorescens SBW25 0.48 PFLU_RS18415 2-hydroxyacid dehydrogenase 0.25 PFLU_RS27760 cell envelope integrity protein CreD low > 109
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS18415 2-hydroxyacid dehydrogenase 0.25 PFLU_RS27760 cell envelope integrity protein CreD low > 109
Bacteroides ovatus ATCC 8483 0.47 BACOVA_04316 4-phosphoerythronate dehydrogenase 0.23 BACOVA_03839 inner membrane protein CreD low > 94
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1575 putative dehydrogenase (NCBI ptt file) 0.23 BT1254 inner membrane protein (NCBI ptt file) low > 81
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS05620 2-hydroxyacid dehydrogenase 0.21 ABZR88_RS19005 cell envelope integrity protein CreD low > 71
Fusobacterium nucleatum SB010 0.28 HUW76_07605 lactate dehydrogenase 0.17 HUW76_10140 cell envelope integrity protein CreD low > 35

Not shown: 26 genomes with orthologs for BWI76_RS12790 only; 12 genomes with orthologs for BWI76_RS04225 only