Conservation of cofitness between BT1607 and BT3762 in Bacteroides thetaiotaomicron VPI-5482

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT1607 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) 1.0 BT3762 arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file) 0.70 19
Bacteroides stercoris CC31F 0.97 HMPREF1181_RS11305 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.81 HMPREF1181_RS03470 arginine repressor low > 56
Bacteroides ovatus ATCC 8483 0.97 BACOVA_04344 tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein 1.00 BACOVA_03592 arginine repressor, C-terminal domain protein 0.85 56
Phocaeicola vulgatus CL09T03C04 0.96 HMPREF1058_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.79 HMPREF1058_RS08855 arginine repressor low > 67
Phocaeicola dorei CL03T12C01 0.96 ABI39_RS10870 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.79 ABI39_RS02985 arginine repressor 0.58 62
Parabacteroides merdae CL09T00C40 0.84 HMPREF1078_RS14700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.45 HMPREF1078_RS10565 arginine repressor low > 61
Erwinia tracheiphila SCR3 0.44 LU632_RS15195 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.18 LU632_RS21370 argR transcriptional regulator ArgR — —
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.18 CSW01_02265 arginine repressor low > 62
Dickeya dianthicola ME23 0.43 DZA65_RS15960 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 DZA65_RS03125 transcriptional regulator ArgR — —
Dickeya dianthicola 67-19 0.43 HGI48_RS15155 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 HGI48_RS03130 transcriptional regulator ArgR — —
Rahnella sp. WP5 0.43 EX31_RS22835 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 EX31_RS12790 ArgR family transcriptional regulator — —
Dickeya dadantii 3937 0.43 DDA3937_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 DDA3937_RS02965 transcriptional regulator ArgR — —
Shewanella sp. ANA-3 0.43 Shewana3_2663 methenyltetrahydrofolate cyclohydrolase (RefSeq) 0.18 Shewana3_3510 arginine repressor (RefSeq) — —
Alteromonas macleodii MIT1002 0.43 MIT1002_02770 hypothetical protein 0.19 MIT1002_03493 Arginine repressor — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF4447 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.20 GFF931 Arginine pathway regulatory protein ArgR, repressor of arg regulon — —
Shewanella oneidensis MR-1 0.43 SO1792 folD methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) 0.18 SO0769 argR arginine repressor (NCBI ptt file) — —
Pectobacterium carotovorum WPP14 0.42 HER17_RS06505 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 HER17_RS18395 transcriptional regulator ArgR — —
Pantoea sp. MT58 0.42 IAI47_14320 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.19 IAI47_02515 transcriptional regulator ArgR — —
Escherichia coli ECRC102 0.41 NIAGMN_05860 Bifunctional protein FolD 0.17 NIAGMN_15550 argR transcriptional regulator ArgR — —
Escherichia coli ECRC101 0.41 MCAODC_27025 Bifunctional protein FolD 0.17 MCAODC_08310 argR transcriptional regulator ArgR — —
Escherichia coli ECRC62 0.41 BNILDI_22225 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.17 BNILDI_01945 argR transcriptional regulator ArgR — —
Escherichia coli ECOR38 0.41 HEPCGN_06445 Bifunctional protein FolD 0.21 HEPCGN_10055 ArgR family transcriptional regulator — —
Escherichia coli ECOR27 0.41 NOLOHH_00795 Bifunctional protein FolD 0.17 NOLOHH_09590 argR transcriptional regulator ArgR — —
Escherichia coli ECRC99 0.41 KEDOAH_20165 Bifunctional protein FolD 0.17 KEDOAH_10360 argR transcriptional regulator ArgR — —
Escherichia coli Nissle 1917 0.41 ECOLIN_RS03065 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.21 ECOLIN_RS24635 arginine repressor — —
Escherichia coli BW25113 0.41 b0529 folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) 0.17 b3237 argR arginine repressor (NCBI) — —
Klebsiella michiganensis M5al 0.41 BWI76_RS07100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.18 BWI76_RS25425 arginine repressor — —
Escherichia coli ECRC98 0.41 JDDGAC_11455 Bifunctional protein FolD 0.17 JDDGAC_21415 argR transcriptional regulator ArgR — —
Escherichia coli ECRC101 0.41 OKFHMN_07805 Bifunctional protein FolD 0.17 OKFHMN_17790 argR transcriptional regulator ArgR — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.41 OHPLBJKB_03152 Bifunctional protein FolD protein 0.17 OHPLBJKB_00467 Arginine repressor — —
Escherichia fergusonii Becca 0.41 EFB2_03532 Bifunctional protein FolD protein 0.21 EFB2_04287 Arginine repressor — —
Serratia liquefaciens MT49 0.41 IAI46_05400 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.18 IAI46_01815 transcriptional regulator ArgR — —
Shewanella amazonensis SB2B 0.41 Sama_1222 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.18 Sama_0671 arginine repressor (RefSeq) — —
Enterobacter asburiae PDN3 0.41 EX28DRAFT_2449 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.19 EX28DRAFT_3448 transcriptional regulator, ArgR family — —
Mycobacterium tuberculosis H37Rv 0.35 Rv3356c Probable bifunctional protein FolD: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase 0.31 Rv1657 Probable arginine repressor ArgR (AHRC) — —
Bifidobacterium breve UCC2003 0.33 BBR_RS14270 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.24 BBR_RS13910 arginine repressor — —

Not shown: 66 genomes with orthologs for BT1607 only; 0 genomes with orthologs for BT3762 only