Conservation of cofitness between b1850 and b4322 in Escherichia coli BW25113

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 1.0 b4322 uxuA mannonate dehydratase (NCBI) 0.37 11
Escherichia coli ECRC62 1.00 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 BNILDI_07705 uxuA mannonate dehydratase — —
Escherichia fergusonii Becca 1.00 EFB2_02093 KHG/KDPG aldolase 1.00 EFB2_04122 Mannonate dehydratase low > 86
Escherichia coli ECRC101 1.00 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 OKFHMN_11565 uxuA mannonate dehydratase — —
Escherichia coli ECRC101 1.00 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 MCAODC_02080 uxuA mannonate dehydratase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01879 KHG/KDPG aldolase 1.00 OHPLBJKB_03745 Mannonate dehydratase low > 73
Escherichia coli ECRC99 1.00 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.99 KEDOAH_16580 uxuA mannonate dehydratase — —
Escherichia coli ECOR38 1.00 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 HEPCGN_09575 uxuA mannonate dehydratase low > 85
Escherichia coli BL21 1.00 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 1.00 ECD_04191 mannonate hydrolase — —
Escherichia coli ECRC102 1.00 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NIAGMN_09415 uxuA mannonate dehydratase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 ECOLIN_RS24835 mannonate dehydratase — —
Escherichia coli ECRC98 1.00 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 JDDGAC_15160 uxuA mannonate dehydratase — —
Escherichia coli ECOR27 0.99 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NOLOHH_03890 uxuA mannonate dehydratase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.93 GFF3093 Mannonate dehydratase (EC 4.2.1.8) low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_0706 Entner-Doudoroff aldolase 0.78 EX28DRAFT_0390 mannonate dehydratase low > 76
Enterobacter sp. TBS_079 0.96 MPMX20_02755 KHG/KDPG aldolase 0.78 MPMX20_03137 Mannonate dehydratase low > 85
Pectobacterium carotovorum WPP14 0.91 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.77 HER17_RS16140 mannonate dehydratase low > 75
Dickeya dadantii 3937 0.91 DDA3937_RS10140 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.79 DDA3937_RS00370 mannonate dehydratase low > 74
Dickeya dianthicola 67-19 0.91 HGI48_RS10170 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.78 HGI48_RS21000 mannonate dehydratase low > 71
Dickeya dianthicola ME23 0.91 DZA65_RS10585 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.79 DZA65_RS21985 mannonate dehydratase low > 75
Pantoea sp. MT58 0.89 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.71 IAI47_01440 mannonate dehydratase low > 76
Rahnella sp. WP5 0.88 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.74 EX31_RS06665 mannonate dehydratase low > 89
Serratia liquefaciens MT49 0.88 IAI46_14570 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.78 IAI46_17280 mannonate dehydratase low > 86
Klebsiella michiganensis M5al 0.87 BWI76_RS18095 ketohydroxyglutarate aldolase 0.96 BWI76_RS05650 mannonate dehydratase — —
Sinorhizobium meliloti 1021 0.48 SMc03153 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.54 SM_b20446 mannonate dehydratase low > 103
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_05150 keto-deoxy-phosphogluconate aldolase 0.65 AO356_28530 mannonate dehydratase — —
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_1903 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.29 PfGW456L13_3477 Mannonate dehydratase (EC 4.2.1.8) — —
Agrobacterium fabrum C58 0.46 Atu4494 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.54 Atu3257 mannonate dehydratase — —
Bosea sp. OAE506 0.45 ABIE41_RS23505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.53 ABIE41_RS18530 mannonate dehydratase low > 77
Rhizobium sp. OAE497 0.44 ABIE40_RS16720 2-dehydro-3-deoxy-phosphogluconate aldolase 0.49 ABIE40_RS22400 mannonate dehydratase — —
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS16730 2-dehydro-3-deoxyphosphogluconate aldolase 0.33 BPHYT_RS28515 mannonate dehydratase — —
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04277 2-keto-3-deoxy-phosphogluconate aldolase 0.33 H281DRAFT_02953 D-mannonate dehydratase (EC 4.2.1.8) — —
Azospirillum brasilense Sp245 0.39 AZOBR_RS29850 ketohydroxyglutarate aldolase 0.55 AZOBR_RS31370 mannonate dehydratase — —
Parabacteroides merdae CL09T00C40 0.22 HMPREF1078_RS05610 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 HMPREF1078_RS13635 mannonate dehydratase low > 61
Bacteroides stercoris CC31F 0.21 HMPREF1181_RS15440 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 HMPREF1181_RS02210 mannonate dehydratase low > 56
Bacteroides ovatus ATCC 8483 0.20 BACOVA_03829 KDPG and KHG aldolase 0.65 BACOVA_00858 mannonate dehydratase low > 94
Phocaeicola vulgatus CL09T03C04 0.20 HMPREF1058_RS01685 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 HMPREF1058_RS11755 mannonate dehydratase low > 67
Phocaeicola dorei CL03T12C01 0.20 ABI39_RS15380 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 ABI39_RS05150 mannonate dehydratase low > 72
Bacteroides thetaiotaomicron VPI-5482 0.20 BT0489 putative gluconate aldolase (NCBI ptt file) 0.65 BT1432 mannonate dehydratase (NCBI ptt file) — —

Not shown: 46 genomes with orthologs for b1850 only; 5 genomes with orthologs for b4322 only