Conservation of cofitness between b1095 and b3803 in Escherichia coli BW25113

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1095 fabF 3-oxoacyl-(acyl carrier protein) synthase (NCBI) 1.0 b3803 hemX predicted uroporphyrinogen III methylase (NCBI) 0.41 2
Escherichia coli BL21 1.00 ECD_01091 3-oxoacyl-[acyl-carrier-protein] synthase II 0.92 ECD_03678 putative uroporphyrinogen III methyltransferase — —
Escherichia fergusonii Becca 1.00 EFB2_02880 3-oxoacyl-[acyl-carrier-protein] synthase 2 0.92 EFB2_04835 Protein HemX low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS06325 beta-ketoacyl-ACP synthase II 0.92 ECOLIN_RS21825 uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECRC102 1.00 NIAGMN_24265 fabF beta-ketoacyl-ACP synthase II 0.92 NIAGMN_12215 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECOR27 1.00 NOLOHH_21095 fabF beta-ketoacyl-ACP synthase II 0.94 NOLOHH_06605 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECRC99 1.00 KEDOAH_24190 fabF beta-ketoacyl-ACP synthase II 0.92 KEDOAH_13690 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECRC98 1.00 JDDGAC_07225 fabF beta-ketoacyl-ACP synthase II 0.92 JDDGAC_18085 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECRC101 1.00 MCAODC_22925 fabF beta-ketoacyl-ACP synthase II 0.92 MCAODC_04965 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECRC101 1.00 OKFHMN_03565 fabF beta-ketoacyl-ACP synthase II 0.92 OKFHMN_14460 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli ECOR38 1.00 HEPCGN_23915 fabF beta-ketoacyl-ACP synthase II 0.92 HEPCGN_13180 hemX uroporphyrinogen-III C-methyltransferase low > 85
Escherichia coli ECRC62 1.00 BNILDI_19255 fabF beta-ketoacyl-ACP synthase II 0.94 BNILDI_04930 hemX uroporphyrinogen-III C-methyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02571 3-oxoacyl-[acyl-carrier-protein] synthase 2 0.96 OHPLBJKB_04250 Protein HemX 0.33 61
Enterobacter asburiae PDN3 0.93 EX28DRAFT_1834 beta-ketoacyl-acyl-carrier-protein synthase II 0.71 EX28DRAFT_4472 Uncharacterized enzyme of heme biosynthesis low > 76
Klebsiella michiganensis M5al 0.93 BWI76_RS11100 beta-ketoacyl-[acyl-carrier-protein] synthase II 0.69 BWI76_RS01170 uroporphyrinogen-III C-methyltransferase low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_01775 3-oxoacyl-[acyl-carrier-protein] synthase 2 0.74 MPMX20_04472 Protein HemX low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF3377 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) 0.82 GFF227 Homolog of E. coli HemX protein 0.82 43
Pectobacterium carotovorum WPP14 0.89 HER17_RS08660 beta-ketoacyl-ACP synthase II 0.52 HER17_RS01305 uroporphyrinogen-III C-methyltransferase low > 75
Pantoea sp. MT58 0.88 IAI47_12060 beta-ketoacyl-ACP synthase II 0.62 IAI47_18435 uroporphyrinogen-III C-methyltransferase low > 76
Rahnella sp. WP5 0.88 EX31_RS24445 beta-ketoacyl-ACP synthase II 0.61 EX31_RS15135 uroporphyrinogen-III C-methyltransferase low > 89
Serratia liquefaciens MT49 0.88 IAI46_09800 beta-ketoacyl-ACP synthase II 0.63 IAI46_00685 uroporphyrinogen-III C-methyltransferase low > 86
Dickeya dianthicola ME23 0.86 DZA65_RS13645 beta-ketoacyl-ACP synthase II 0.55 DZA65_RS21130 uroporphyrinogen-III C-methyltransferase low > 75
Dickeya dadantii 3937 0.86 DDA3937_RS13110 beta-ketoacyl-ACP synthase II 0.56 DDA3937_RS19930 uroporphyrinogen-III C-methyltransferase low > 74
Dickeya dianthicola 67-19 0.85 HGI48_RS13175 beta-ketoacyl-ACP synthase II 0.55 HGI48_RS20085 uroporphyrinogen-III C-methyltransferase low > 71
Erwinia tracheiphila SCR3 0.84 LU632_RS14810 fabF beta-ketoacyl-ACP synthase II 0.61 LU632_RS24170 hemX uroporphyrinogen-III C-methyltransferase low > 74
Shewanella amazonensis SB2B 0.78 Sama_1978 3-oxoacyl-(acyl-carrier-protein) synthase II (RefSeq) 0.24 Sama_3256 hemX protein (RefSeq) low > 62
Shewanella loihica PV-4 0.75 Shew_1605 beta-ketoacyl synthase (RefSeq) 0.20 Shew_0316 protein of unknown function DUF513, hemX (RefSeq) — —
Alteromonas macleodii MIT1002 0.71 MIT1002_01735 3-oxoacyl-[acyl-carrier-protein] synthase 2 0.20 MIT1002_00100 Putative uroporphyrinogen-III C-methyltransferase — —
Pseudomonas sp. S08-1 0.70 OH686_22150 beta-ketoacyl-acyl-carrier-protein synthase II 0.10 OH686_13910 Uncharacterized protein EC-HemX low > 80
Pseudomonas putida KT2440 0.68 PP_1916 beta-ketoacyl-ACP synthase II / 3-oxo-cis-vaccenoyl-[acp] synthase / FabF / KASII / acetoacetyl-[acp] synthase 0.12 PP_0188 putative Uroporphyrin-III C-methyltransferase — —
Pseudomonas stutzeri RCH2 0.68 Psest_1690 beta-ketoacyl-acyl-carrier-protein synthase II 0.10 Psest_3746 Uncharacterized enzyme of heme biosynthesis — —
Pseudomonas simiae WCS417 0.68 PS417_21430 3-oxoacyl-ACP synthase 0.11 PS417_27520 uroporphyrin-III methyltransferase low > 88
Pseudomonas fluorescens FW300-N2C3 0.67 AO356_20175 3-oxoacyl-ACP synthase 0.12 AO356_12795 heme biosynthesis operon protein HemX low > 104
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_01355 3-oxoacyl-ACP synthase 0.10 AO353_08980 heme biosynthesis operon protein HemX low > 101
Pseudomonas fluorescens GW456-L13 0.64 PfGW456L13_2107 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) 0.11 PfGW456L13_858 Uroporphyrinogen-III synthase (EC 4.2.1.75) 0.44 21
Pseudomonas syringae pv. syringae B728a 0.64 Psyr_1649 3-oxoacyl-[acyl-carrier-protein] synthase II 0.12 Psyr_0060 Protein of unknown function DUF513 — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.64 Psyr_1649 3-oxoacyl-[acyl-carrier-protein] synthase II 0.12 Psyr_0060 Protein of unknown function DUF513 — —
Pseudomonas fluorescens FW300-N1B4 0.64 Pf1N1B4_449 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) 0.12 Pf1N1B4_2187 Uroporphyrinogen-III synthase (EC 4.2.1.75) — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS09615 3-oxoacyl-ACP synthase 0.09 HSERO_RS14655 uroporphyrin-III C-methyltransferase — —

Not shown: 60 genomes with orthologs for b1095 only; 0 genomes with orthologs for b3803 only