| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b2026 | hisI | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | 1.0 | b3772 | ilvA | threonine dehydratase (NCBI) | 0.95 | 7 |
| Escherichia coli BL21 | 1.00 | ECD_01928 | | phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase | 1.00 | ECD_03650 | | l-threonine dehydratase, biosynthetic; also known as threonine deaminase | low | > 60 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS11975 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.99 | ECOLIN_RS21670 | | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECRC102 | 0.99 | NIAGMN_22430 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | NIAGMN_12390 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECRC98 | 0.99 | JDDGAC_28595 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | JDDGAC_18255 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECOR38 | 0.99 | HEPCGN_03190 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.99 | HEPCGN_13345 | ilvA | threonine ammonia-lyase, biosynthetic | low | > 85 |
| Escherichia coli ECRC101 | 0.99 | MCAODC_20455 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | MCAODC_05140 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECRC101 | 0.99 | OKFHMN_24485 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | OKFHMN_14635 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECRC99 | 0.99 | KEDOAH_03665 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | KEDOAH_13515 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia coli ECRC62 | 0.98 | BNILDI_14710 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | BNILDI_04755 | ilvA | threonine ammonia-lyase, biosynthetic | — | — |
| Escherichia fergusonii Becca | 0.98 | EFB2_01830 | | Histidine biosynthesis bifunctional protein HisIE | 0.99 | EFB2_04864 | | L-threonine dehydratase biosynthetic IlvA | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.96 | OHPLBJKB_01674 | | Histidine biosynthesis bifunctional protein HisIE | 1.00 | OHPLBJKB_04281 | | L-threonine dehydratase biosynthetic IlvA | low | > 73 |
| Escherichia coli ECOR27 | 0.92 | NOLOHH_15800 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 1.00 | NOLOHH_06770 | ilvA | threonine ammonia-lyase, biosynthetic | low | > 57 |
| Enterobacter asburiae PDN3 | 0.91 | EX28DRAFT_0533 | | phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) | 0.93 | EX28DRAFT_4444 | | threonine ammonia-lyase, biosynthetic, long form | 0.82 | 29 |
| Enterobacter sp. TBS_079 | 0.91 | MPMX20_03008 | | Histidine biosynthesis bifunctional protein HisIE | 0.93 | MPMX20_04498 | | L-threonine dehydratase biosynthetic IlvA | 0.95 | 2 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.89 | GFF3906 | | Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) | 0.93 | GFF2900 | | Threonine dehydratase biosynthetic (EC 4.3.1.19) | low | > 78 |
| Klebsiella michiganensis M5al | 0.87 | BWI76_RS18955 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase | 0.94 | BWI76_RS00980 | | PLP-dependent threonine dehydratase | 0.89 | 3 |
| Dickeya dadantii 3937 | 0.81 | DDA3937_RS09705 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.86 | DDA3937_RS20150 | | threonine ammonia-lyase, biosynthetic | 0.89 | 23 |
| Pantoea sp. MT58 | 0.81 | IAI47_07060 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.83 | IAI47_01040 | | threonine ammonia-lyase, biosynthetic | 0.97 | 10 |
| Dickeya dianthicola 67-19 | 0.80 | HGI48_RS09715 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.87 | HGI48_RS20290 | | threonine ammonia-lyase, biosynthetic | low | > 71 |
| Dickeya dianthicola ME23 | 0.80 | DZA65_RS10025 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.85 | DZA65_RS21330 | | threonine ammonia-lyase, biosynthetic | 0.89 | 4 |
| Erwinia tracheiphila SCR3 | 0.76 | LU632_RS08915 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.83 | LU632_RS24395 | ilvA | threonine ammonia-lyase, biosynthetic | low | > 74 |
| Rahnella sp. WP5 | 0.76 | EX31_RS11470 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.81 | EX31_RS15010 | | threonine ammonia-lyase, biosynthetic | 0.91 | 50 |
| Serratia liquefaciens MT49 | 0.76 | IAI46_08180 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.84 | IAI46_24340 | | threonine ammonia-lyase, biosynthetic | low | > 86 |
| Pectobacterium carotovorum WPP14 | 0.70 | HER17_RS12260 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.83 | HER17_RS01080 | | threonine ammonia-lyase, biosynthetic | 0.95 | 16 |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_05780 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase | 0.67 | CSW01_00135 | | threonine ammonia-lyase, biosynthetic | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.63 | MIT1002_02639 | | Phosphoribosyl-ATP pyrophosphatase | 0.54 | MIT1002_04040 | | L-threonine dehydratase biosynthetic IlvA | 0.95 | 26 |
| Shewanella oneidensis MR-1 | 0.62 | SO2067 | hisI | phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) | 0.57 | SO4344 | ilvA | threonine dehydratase (NCBI ptt file) | 0.85 | 63 |
| Shewanella amazonensis SB2B | 0.61 | Sama_1948 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) | 0.57 | Sama_3278 | | threonine dehydratase (RefSeq) | 0.88 | 53 |
| Shewanella sp. ANA-3 | 0.60 | Shewana3_1847 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) | 0.56 | Shewana3_0359 | | threonine dehydratase (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.57 | Shew_2204 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) | 0.54 | Shew_0293 | | threonine dehydratase (RefSeq) | 0.96 | 10 |
| Rhodanobacter denitrificans MT42 | 0.56 | LRK55_RS01355 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.45 | LRK55_RS09940 | | threonine ammonia-lyase, biosynthetic | low | > 63 |
| Rhodanobacter sp. FW510-T8 | 0.55 | OKGIIK_04980 | hisIE | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.46 | OKGIIK_13620 | ilvA | threonine ammonia-lyase, biosynthetic | low | > 52 |
| Rhodanobacter denitrificans FW104-10B01 | 0.55 | LRK54_RS01575 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.45 | LRK54_RS10300 | | threonine ammonia-lyase, biosynthetic | low | > 59 |
| Dyella japonica UNC79MFTsu3.2 | 0.54 | ABZR86_RS06700 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.49 | ABZR86_RS15925 | | threonine ammonia-lyase, biosynthetic | low | > 74 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.46 | A4249_RS10720 | | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | 0.49 | A4249_RS00615 | | threonine ammonia-lyase, biosynthetic | 0.98 | 44 |
| Acinetobacter radioresistens SK82 | 0.31 | MPMX26_00264 | | Histidine biosynthesis bifunctional protein HisIE | 0.46 | MPMX26_01278 | | L-threonine dehydratase biosynthetic IlvA | 0.87 | 26 |
Not shown: 13 genomes with orthologs for b2026 only; 33 genomes with orthologs for b3772 only