Conservation of cofitness between b0651 and b2074 in Escherichia coli BW25113

34 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0651 rihA ribonucleoside hydrolase 1 (NCBI) 1.0 b2074 b2074 putative membrane protein (VIMSS) 0.17 3
Escherichia coli BL21 1.00 ECD_00617 ribonucleoside hydrolase 1 0.99 ECD_01979 multidrug efflux system, subunit A low > 60
Escherichia coli ECRC99 1.00 KEDOAH_20695 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 KEDOAH_03950 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECRC101 1.00 OKFHMN_07275 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 OKFHMN_24200 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECRC101 1.00 MCAODC_26490 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 MCAODC_20740 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECRC102 1.00 NIAGMN_05330 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 NIAGMN_22145 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECRC98 1.00 JDDGAC_10920 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 JDDGAC_28310 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECRC62 0.99 BNILDI_21670 rihA pyrimidine-specific ribonucleoside hydrolase RihA 1.00 BNILDI_14460 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli ECOR27 0.99 NOLOHH_23660 rihA pyrimidine-specific ribonucleoside hydrolase RihA 1.00 NOLOHH_15545 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03062 Pyrimidine-specific ribonucleoside hydrolase RihA 1.00 OHPLBJKB_01630 Multidrug resistance protein MdtA low > 73
Escherichia coli ECOR38 0.99 HEPCGN_00955 rihA pyrimidine-specific ribonucleoside hydrolase RihA 0.99 HEPCGN_02890 mdtA multidrug efflux RND transporter subunit MdtA low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS03505 pyrimidine-specific ribonucleoside hydrolase RihA 0.99 ECOLIN_RS12195 multidrug efflux RND transporter subunit MdtA — —
Escherichia fergusonii Becca 0.99 EFB2_03448 Pyrimidine-specific ribonucleoside hydrolase RihA 0.99 EFB2_01781 Multidrug resistance protein MdtA low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF4569 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) 0.78 GFF3855 Multidrug transporter MdtA low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS13490 pyrimidine-specific ribonucleoside hydrolase RihA 0.79 BWI76_RS19250 multidrug transporter subunit MdtA low > 92
Enterobacter sp. TBS_079 0.89 MPMX20_01302 Pyrimidine-specific ribonucleoside hydrolase RihA 0.80 MPMX20_03060 Multidrug resistance protein MdtA low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2320 Inosine-uridine nucleoside N-ribohydrolase 0.78 EX28DRAFT_0484 RND family efflux transporter, MFP subunit low > 76
Serratia liquefaciens MT49 0.62 IAI46_05975 pyrimidine-specific ribonucleoside hydrolase RihA 0.61 IAI46_18970 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 86
Rahnella sp. WP5 0.40 EX31_RS20270 nucleoside hydrolase 0.38 EX31_RS13385 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 89
Pectobacterium carotovorum WPP14 0.37 HER17_RS00105 nucleoside hydrolase 0.62 HER17_RS06325 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 75
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_20845 uridine/adenosine nucleosidase (EC 3.2.2.3; EC 3.2.2.7) (from data) 0.42 AO353_22890 secretion protein HlyD low > 101
Pseudomonas fluorescens FW300-N2E2 0.34 Pf6N2E2_167 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) 0.43 Pf6N2E2_1273 Probable RND efflux membrane fusion protein low > 103
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_6029 uridine nucleosidase (EC 3.2.2.3) (from data) 0.42 Pf1N1B4_4664 RND transporter, membrane fusion protein — —
Ralstonia solanacearum GMI1000 0.34 RS_RS12775 nucleoside hydrolase 0.42 RS_RS22910 multidrug transporter subunit MdtA low > 80
Ralstonia solanacearum PSI07 0.34 RPSI07_RS12145 nucleoside hydrolase 0.42 RPSI07_RS05510 multidrug transporter subunit MdtA low > 81
Pseudomonas fluorescens FW300-N2C3 0.34 AO356_00940 uridine/adenosine nucleosidase (EC 3.2.2.3; EC 3.2.2.7) (from data) 0.43 AO356_25870 secretion protein HlyD low > 104
Pseudomonas simiae WCS417 0.33 PS417_18375 hypothetical protein 0.44 PS417_12740 secretion protein HlyD low > 88
Pseudomonas fluorescens SBW25 0.33 PFLU_RS20350 nucleoside hydrolase 0.44 PFLU_RS13425 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS20350 nucleoside hydrolase 0.44 PFLU_RS13425 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 109
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_3906 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) 0.43 PfGW456L13_3267 RND transporter, membrane fusion protein low > 87
Pseudomonas putida KT2440 0.33 PP_2460 ribonucleoside hydrolase 0.42 PP_3585 multidrug efflux transport system - putative membrane fusion protein low > 96
Bosea sp. OAE506 0.29 ABIE41_RS05160 nucleoside hydrolase 0.24 ABIE41_RS20145 efflux RND transporter periplasmic adaptor subunit low > 77
Xanthomonas campestris pv. campestris strain 8004 0.23 Xcc-8004.1203.1 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) 0.30 Xcc-8004.4791.1 Probable Co/Zn/Cd efflux system membrane fusion protein low > 74
Rhodanobacter denitrificans FW104-10B01 0.19 LRK54_RS11810 nucleoside hydrolase 0.28 LRK54_RS09840 efflux RND transporter periplasmic adaptor subunit low > 59
Rhodanobacter denitrificans MT42 0.19 LRK55_RS11535 nucleoside hydrolase 0.28 LRK55_RS09500 efflux RND transporter periplasmic adaptor subunit low > 63

Not shown: 13 genomes with orthologs for b0651 only; 21 genomes with orthologs for b2074 only