Conservation of cofitness between b0003 and b0002 in Escherichia coli BW25113

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0003 thrB homoserine kinase (NCBI) 1.0 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.96 2
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03657 Homoserine kinase 0.99 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli BL21 1.00 ECD_00003 homoserine kinase 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.89 1
Escherichia coli ECRC62 1.00 BNILDI_08165 thrB homoserine kinase 0.99 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECOR27 1.00 NOLOHH_03435 thrB homoserine kinase 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 57
Escherichia coli ECOR38 1.00 HEPCGN_09110 thrB homoserine kinase 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 85
Escherichia coli ECRC101 1.00 OKFHMN_11105 thrB homoserine kinase 1.00 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC99 1.00 KEDOAH_17050 thrB homoserine kinase 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC98 1.00 JDDGAC_14700 thrB homoserine kinase 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia fergusonii Becca 1.00 EFB2_04040 Homoserine kinase 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00015 homoserine kinase 1.00 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 52
Escherichia coli ECRC102 1.00 NIAGMN_08955 thrB homoserine kinase 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 1.00 MCAODC_01620 thrB homoserine kinase 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF1079 Homoserine kinase (EC 2.7.1.39) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter asburiae PDN3 0.91 EX28DRAFT_3615 homoserine kinase (EC 2.7.1.39) 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) — —
Enterobacter sp. TBS_079 0.91 MPMX20_00711 Homoserine kinase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.97 2
Klebsiella michiganensis M5al 0.89 BWI76_RS04250 homoserine kinase 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 1
Pantoea sp. MT58 0.82 IAI47_16210 homoserine kinase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 1
Pectobacterium carotovorum WPP14 0.81 HER17_RS02800 homoserine kinase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.81 58
Dickeya dadantii 3937 0.81 DDA3937_RS18410 homoserine kinase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 1
Rahnella sp. WP5 0.81 EX31_RS03940 homoserine kinase 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 20
Dickeya dianthicola ME23 0.81 DZA65_RS19480 homoserine kinase 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 1
Dickeya dianthicola 67-19 0.81 HGI48_RS18340 homoserine kinase 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 7
Serratia liquefaciens MT49 0.80 IAI46_03035 homoserine kinase 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 10
Erwinia tracheiphila SCR3 0.77 LU632_RS02615 thrB homoserine kinase 0.82 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 1
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_11970 homoserine kinase 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella loihica PV-4 0.53 Shew_1080 homoserine kinase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.92 21
Shewanella amazonensis SB2B 0.52 Sama_0906 homoserine kinase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.97 2
Shewanella oneidensis MR-1 0.52 SO3414 thrB homoserine kinase (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.90 46
Shewanella sp. ANA-3 0.51 Shewana3_1140 homoserine kinase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.96 2
Alteromonas macleodii MIT1002 0.49 MIT1002_03085 Homoserine kinase 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.97 11
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS18955 homoserine kinase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.22 Echvi_2001 homoserine kinase (EC 2.7.1.39) (from data) 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.98 1
Pedobacter sp. GW460-11-11-14-LB5 0.22 CA265_RS23470 homoserine kinase (EC 2.7.1.39) (from data) 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.98 1
Lysobacter sp. OAE881 0.18 ABIE51_RS17525 homoserine kinase 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 3
Xanthomonas campestris pv. campestris strain 8004 0.17 Xcc-8004.2956.1 Homoserine kinase (EC 2.7.1.39) 0.34 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.78 12

Not shown: 7 genomes with orthologs for b0003 only; 6 genomes with orthologs for b0002 only