Conservation of cofitness between SMc00813 and SMc04350 in Sinorhizobium meliloti 1021

39 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc00813 transport transmembrane protein 1.0 SMc04350 multidrug efflux system transmembrane protein 0.37 13
Agrobacterium fabrum C58 0.71 Atu0621 MFS permease 0.28 Atu5177 efflux protein low > 89
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS07670 major facilitator transporter 0.28 HSERO_RS10245 hemolysin secretion protein D low > 78
Azospirillum sp. SherDot2 0.46 MPMX19_02331 putative transport protein HsrA 0.31 MPMX19_03089 Macrolide export protein MacA low > 112
Azospirillum brasilense Sp245 0.45 AZOBR_RS03675 major facilitator transporter 0.30 AZOBR_RS27335 hemolysin secretion protein D low > 97
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS14740 MFS transporter 0.27 QEN71_RS35170 macrolide transporter subunit MacA low > 153
Xanthomonas campestris pv. campestris strain 8004 0.40 Xcc-8004.2186.1 Drug resistance translocase 0.10 Xcc-8004.4963.1 Acriflavin resistance protein low > 74
Serratia liquefaciens MT49 0.38 IAI46_11730 MFS transporter 0.32 IAI46_18480 efflux RND transporter periplasmic adaptor subunit low > 86
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS30530 MFS transporter 0.30 RR42_RS26395 hemolysin secretion protein D low > 128
Rhodospirillum rubrum S1H 0.37 Rru_A3056 Major facilitator superfamily MFS_1 (NCBI) 0.32 Rru_A3235 Secretion protein HlyD (NCBI) low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.35 GFF1703 Permeases of the major facilitator superfamily 0.31 GFF4905 Macrolide-specific efflux protein MacA low > 78
Escherichia coli BL21 0.35 ECD_03640 putative multidrug or homocysteine efflux system 0.32 ECD_00883 macrolide transporter membrane fusion protein (MFP) component low > 61
Escherichia coli ECRC100 0.35 OKFHMN_14720 hsrA putative transport protein HsrA 0.32 OKFHMN_05810 macA macrolide transporter subunit MacA low > 80
Escherichia coli BW25113 0.35 b3754 hsrA predicted multidrug or homocysteine efflux system (NCBI) 0.32 b0878 b0878 putative membrane protein (VIMSS) low > 76
Escherichia coli ECOR38 0.35 HEPCGN_13430 hsrA putative transport protein HsrA 0.32 HEPCGN_22875 macA macrolide transporter subunit MacA low > 87
Escherichia coli ECRC98 0.35 JDDGAC_18340 hsrA putative transport protein HsrA 0.32 JDDGAC_09445 macA macrolide transporter subunit MacA low > 86
Escherichia coli ECRC99 0.35 KEDOAH_13430 hsrA putative transport protein HsrA 0.32 KEDOAH_22100 macA macrolide transporter subunit MacA — —
Escherichia coli ECRC102 0.35 NIAGMN_12475 hsrA putative transport protein HsrA 0.32 NIAGMN_03850 macA macrolide transporter subunit MacA — —
Escherichia coli ECRC101 0.35 MCAODC_05225 hsrA putative transport protein HsrA 0.32 MCAODC_25025 macA macrolide transporter subunit MacA low > 87
Escherichia fergusonii Becca 0.35 EFB2_04879 putative transport protein HsrA 0.32 EFB2_03183 Macrolide export protein MacA low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_04296 putative transport protein HsrA 0.32 OHPLBJKB_02790 Macrolide export protein MacA low > 73
Escherichia coli Nissle 1917 0.35 ECOLIN_RS21590 multidrug transporter subunit MdtD 0.32 ECOLIN_RS04675 macrolide transporter subunit MacA — —
Escherichia coli ECRC62 0.35 BNILDI_04670 hsrA putative transport protein HsrA 0.32 BNILDI_20460 macA macrolide transporter subunit MacA low > 75
Escherichia coli ECOR27 0.35 NOLOHH_06855 hsrA putative transport protein HsrA 0.32 NOLOHH_22205 macA macrolide transporter subunit MacA low > 75
Variovorax sp. SCN45 0.35 GFF279 Uncharacterized MFS-type transporter 0.31 GFF1292 Macrolide-specific efflux protein MacA low > 127
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1079 Permeases of the major facilitator superfamily 0.32 PfGW456L13_2393 pyoverdine-specific efflux macA-like protein low > 87
Enterobacter asburiae PDN3 0.34 EX28DRAFT_4030 drug resistance transporter, EmrB/QacA subfamily 0.32 EX28DRAFT_2054 RND family efflux transporter, MFP subunit low > 76
Enterobacter sp. TBS_079 0.34 MPMX20_04613 putative transport protein HsrA 0.33 MPMX20_01540 Macrolide export protein MacA low > 85
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2413 Permeases of the major facilitator superfamily 0.32 Pf1N1B4_134 pyoverdine-specific efflux macA-like protein low > 87
Pseudomonas sp. RS175 0.34 PFR28_04171 putative transport protein HsrA 0.34 PFR28_02868 Macrolide export protein MacA low > 88
Pseudomonas fluorescens FW300-N2E2 0.34 Pf6N2E2_4674 Permeases of the major facilitator superfamily 0.34 Pf6N2E2_20 pyoverdine-specific efflux macA-like protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.34 AO356_13775 EmrB/QacA subfamily drug resistance transporter 0.34 AO356_21170 hemolysin secretion protein D low > 104
Pseudomonas putida KT2440 0.30 PP_4951 Drug resistance transporter, EmrB/QacA family 0.32 PP_4209 ABC export system, membrane fusion protein low > 96
Pseudomonas simiae WCS417 0.30 PS417_26365 EmrB/QacA subfamily drug resistance transporter 0.31 PS417_17635 hemolysin secretion protein D low > 88
Acinetobacter radioresistens SK82 0.30 MPMX26_00132 Putative multidrug resistance protein MdtD 0.32 MPMX26_00467 Macrolide export protein MacA low > 36
Pectobacterium carotovorum WPP14 0.29 HER17_RS06310 MFS transporter 0.29 HER17_RS17200 efflux RND transporter periplasmic adaptor subunit low > 75
Pseudomonas syringae pv. syringae B728a 0.28 Psyr_4769 Major facilitator superfamily 0.32 Psyr_2617 Secretion protein HlyD low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.28 Psyr_4769 Major facilitator superfamily 0.32 Psyr_2617 Secretion protein HlyD low > 86
Dickeya dianthicola ME23 0.27 DZA65_RS16175 MFS transporter 0.29 DZA65_RS04325 efflux RND transporter periplasmic adaptor subunit low > 75
Dickeya dadantii 3937 0.26 DDA3937_RS15275 multidrug transporter subunit MdtD 0.29 DDA3937_RS04450 efflux RND transporter periplasmic adaptor subunit low > 74

Not shown: 23 genomes with orthologs for SMc00813 only; 18 genomes with orthologs for SMc04350 only