Conservation of cofitness between PP_2601 and PP_4977 in Pseudomonas putida KT2440

34 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2601 Transcriptional regulator, IclR family 1.0 PP_4977 5,10-methylenetetrahydrofolate reductase 0.19 6
Pseudomonas fluorescens FW300-N1B4 0.77 Pf1N1B4_2744 Transcriptional regulator, IclR family 0.86 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 87
Pseudomonas fluorescens GW456-L13 0.76 PfGW456L13_1419 Transcriptional regulator, IclR family 0.87 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 87
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_06220 IclR family transcriptional regulator 0.88 AO353_08015 5,10-methylenetetrahydrofolate reductase low > 101
Pseudomonas sp. RS175 0.72 PFR28_03817 Transcriptional repressor IclR 0.87 PFR28_04202 5,10-methylenetetrahydrofolate reductase low > 88
Hydrogenophaga sp. GW460-11-11-14-LB1 0.51 GFF3860 Transcriptional regulator, IclR family 0.58 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Variovorax sp. OAS795 0.50 ABID97_RS29345 IclR family transcriptional regulator 0.54 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] low > 91
Paraburkholderia bryophila 376MFSha3.1 0.49 H281DRAFT_01807 transcriptional regulator, IclR family 0.55 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P)) low > 103
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS38820 IclR family transcriptional regulator 0.55 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] low > 153
Burkholderia phytofirmans PsJN 0.48 BPHYT_RS20440 IclR family transcriptional regulator 0.55 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase low > 109
Variovorax sp. SCN45 0.47 GFF1520 Transcriptional regulator, IclR family 0.55 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 127
Paraburkholderia graminis OAS925 0.40 ABIE53_001907 IclR family acetate operon transcriptional repressor 0.55 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH) low > 113
Pseudomonas fluorescens FW300-N2C3 0.32 AO356_27445 IclR family transcriptional regulator 0.87 AO356_13605 5,10-methylenetetrahydrofolate reductase low > 104
Pseudomonas fluorescens FW300-N2E2 0.31 Pf6N2E2_863 Transcriptional regulator, IclR family 0.87 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 103
Agrobacterium fabrum C58 0.29 Atu4599 IclR family transcriptional regulator 0.31 Atu2123 methylenetetrahydrofolate reductase low > 89
Enterobacter sp. TBS_079 0.21 MPMX20_00234 Transcriptional repressor IclR 0.37 MPMX20_04529 5,10-methylenetetrahydrofolate reductase low > 85
Enterobacter asburiae PDN3 0.20 EX28DRAFT_4327 transcriptional regulator, IclR family 0.36 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form low > 76
Pectobacterium carotovorum WPP14 0.20 HER17_RS02305 glyoxylate bypass operon transcriptional repressor IclR 0.35 HER17_RS00950 methylenetetrahydrofolate reductase low > 75
Klebsiella michiganensis M5al 0.20 BWI76_RS01680 transcriptional regulator IclR 0.36 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.27 58
Escherichia coli ECRC62 0.20 BNILDI_06135 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 BNILDI_05725 metF methylenetetrahydrofolate reductase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.20 OHPLBJKB_04031 Transcriptional repressor IclR 0.36 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase low > 73
Escherichia coli Nissle 1917 0.20 ECOLIN_RS23155 glyoxylate bypass operon transcriptional repressor IclR 0.36 ECOLIN_RS22760 methylenetetrahydrofolate reductase low > 52
Escherichia coli ECOR38 0.20 HEPCGN_11890 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 HEPCGN_12310 metF methylenetetrahydrofolate reductase low > 85
Escherichia coli BL21 0.20 ECD_03890 transcriptional repressor 0.36 ECD_03827 5,10-methylenetetrahydrofolate reductase low > 60
Escherichia coli ECRC102 0.20 NIAGMN_10995 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 0.20 MCAODC_03745 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 MCAODC_04165 metF methylenetetrahydrofolate reductase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.20 GFF1356 Acetate operon repressor 0.36 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 78
Escherichia coli ECRC99 0.20 KEDOAH_14915 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli ECOR27 0.20 NOLOHH_05385 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 NOLOHH_05810 metF methylenetetrahydrofolate reductase low > 57
Escherichia coli BW25113 0.20 b4018 iclR repressor of aceBA operon (VIMSS) 0.36 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.70 22
Escherichia coli ECRC101 0.20 OKFHMN_13245 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 OKFHMN_13665 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC98 0.20 JDDGAC_16870 iclR glyoxylate bypass operon transcriptional repressor IclR 0.36 JDDGAC_17290 metF methylenetetrahydrofolate reductase
Escherichia fergusonii Becca 0.20 EFB2_04593 Transcriptional repressor IclR 0.36 EFB2_04672 5,10-methylenetetrahydrofolate reductase low > 86
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS01425 IclR family transcriptional regulator 0.19 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] low > 61
Shewanella sp. ANA-3 0.11 Shewana3_1275 IclR family transcriptional regulator (RefSeq) 0.36 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) low > 73

Not shown: 1 genomes with orthologs for PP_2601 only; 65 genomes with orthologs for PP_4977 only