Conservation of cofitness between NOLOHH_15540 and NOLOHH_16680 in Escherichia coli ECOR27

39 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 NOLOHH_16680 yecE UPF0759 protein YecE 0.60 6
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_00810 yecE UPF0759 protein YecE low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_26235 yecE UPF0759 protein YecE low > 80
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_19170 yecE UPF0759 protein YecE low > 87
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_01825 yecE UPF0759 protein YecE — —
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_01870 yecE UPF0759 protein YecE — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.90 ECOLIN_RS10685 DUF72 domain-containing protein low > 55
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b1868 yecE hypothetical protein (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.99 EFB2_02074 hypothetical protein low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_01860 hypothetical protein low > 73
Escherichia coli BL21 1.00 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_01839 UPF0759 family protein — —
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_15470 yecE UPF0759 protein YecE low > 75
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_04645 yecE UPF0759 protein YecE low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.85 GFF1649 FIG003003: hypothetical protein low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.81 BWI76_RS18180 hypothetical protein low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.82 MPMX20_02773 hypothetical protein low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.83 EX28DRAFT_0689 Uncharacterized conserved protein low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 IAI46_14660 DUF72 domain-containing protein low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.62 IAI47_08420 DUF72 domain-containing protein low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.69 LU632_RS13445 DUF72 domain-containing protein low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 HER17_RS11875 DUF72 domain-containing protein low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 DDA3937_RS10050 DUF72 domain-containing protein low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.61 DZA65_RS10490 DUF72 domain-containing protein low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.62 HGI48_RS10080 DUF72 domain-containing protein low > 71
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.30 PFR28_00372 hypothetical protein low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.31 AO356_06165 hypothetical protein low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.60 EX31_RS17275 DUF72 domain-containing protein low > 89
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.35 PP_1509 conserved protein of unknown function low > 96
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.30 Pf6N2E2_3099 FIG003003: hypothetical protein low > 103
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.32 PfGW456L13_4736 FIG003003: hypothetical protein low > 87
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.35 OH686_06775 UPF0759 protein YecE low > 80
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.31 AO353_16330 hypothetical protein low > 101
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.33 PFLU_RS06150 DUF72 domain-containing protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.33 PFLU_RS06150 DUF72 domain-containing protein low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.34 PS417_06080 hypothetical protein low > 88
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.30 Pf1N1B4_3055 FIG003003: hypothetical protein low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.10 QEN71_RS13175 DUF72 domain-containing protein low > 153
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.34 Psyr_1322 Protein of unknown function DUF72 low > 86
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.34 Psyr_1322 Protein of unknown function DUF72 low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.33 Psest_1561 Uncharacterized conserved protein low > 67

Not shown: 27 genomes with orthologs for NOLOHH_15540 only; 9 genomes with orthologs for NOLOHH_16680 only