Conservation of cofitness between HER17_RS01300 and HER17_RS16005 in Pectobacterium carotovorum WPP14

26 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Pectobacterium carotovorum WPP14	1.0	HER17_RS01300		protoheme IX biogenesis protein HemY	1.0	HER17_RS16005		peroxiredoxin C	0.76	5
Serratia liquefaciens MT49	0.79	IAI46_00680		protoheme IX biogenesis protein HemY	0.93	IAI46_04825		peroxiredoxin C	low	> 86
Dickeya dadantii 3937	0.76	DDA3937_RS19935		protoheme IX biogenesis protein HemY	0.94	DDA3937_RS05455		peroxiredoxin C	—	—
Rahnella sp. WP5	0.75	EX31_RS15130		protoheme IX biogenesis protein HemY	0.91	EX31_RS22080		peroxiredoxin C	low	> 89
Dickeya dianthicola ME23	0.74	DZA65_RS21135		protoheme IX biogenesis protein HemY	0.94	DZA65_RS05840		peroxiredoxin C	low	> 75
Dickeya dianthicola 67-19	0.74	HGI48_RS20090		protoheme IX biogenesis protein HemY	0.94	HGI48_RS05515		peroxiredoxin C	—	—
Erwinia tracheiphila SCR3	0.73	LU632_RS24175	hemY	protoheme IX biogenesis protein HemY	0.92	LU632_RS18475		peroxiredoxin C	low	> 74
Enterobacter sp. TBS_079	0.71	MPMX20_04473		Protein HemY	0.91	MPMX20_00994		Alkyl hydroperoxide reductase C	low	> 85
Enterobacter asburiae PDN3	0.71	EX28DRAFT_4471		heme biosynthesis-associated TPR protein	0.91	EX28DRAFT_2568		Peroxiredoxin	low	> 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.69	GFF226		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.89	GFF4302		Alkyl hydroperoxide reductase subunit C-like protein	low	> 78
Klebsiella michiganensis M5al	0.69	BWI76_RS01165		protoheme IX biogenesis protein HemY	0.89	BWI76_RS06285		peroxiredoxin	low	> 92
Vibrio cholerae E7946 ATCC 55056	0.25	CSW01_00595		heme biosynthesis protein HemY	0.75	CSW01_03815		peroxidase	low	> 62
Kangiella aquimarina DSM 16071	0.18	B158DRAFT_0255		Uncharacterized enzyme of heme biosynthesis	0.77	B158DRAFT_1235		Peroxiredoxin	low	> 40
Pseudomonas fluorescens FW300-N2E2	0.15	Pf6N2E2_4433		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.69	Pf6N2E2_5586		Alkyl hydroperoxide reductase subunit C-like protein	low	> 103
Pseudomonas fluorescens FW300-N2C3	0.14	AO356_12800		heme biosynthesis protein HemY	0.69	AO356_18305		alkyl hydroperoxide reductase	low	> 104
Pseudomonas simiae WCS417	0.13	PS417_27515		heme biosynthesis protein HemY	0.68	PS417_05620		alkyl hydroperoxide reductase	low	> 88
Pseudomonas fluorescens GW456-L13	0.13	PfGW456L13_859		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.69	PfGW456L13_1745		Alkyl hydroperoxide reductase subunit C-like protein	low	> 87
Pseudomonas fluorescens FW300-N2E3	0.13	AO353_08975		heme biosynthesis protein HemY	0.70	AO353_04125		alkyl hydroperoxide reductase	low	> 101
Alteromonas macleodii MIT1002	0.13	MIT1002_00099		putative protoheme IX biogenesis protein	0.77	MIT1002_01241		putative peroxiredoxin	low	> 70
Pseudomonas fluorescens FW300-N1B4	0.13	Pf1N1B4_2188		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.69	Pf1N1B4_746		Alkyl hydroperoxide reductase subunit C-like protein	—	—
Shewanella sp. ANA-3	0.12	Shewana3_0383		HemY domain-containing protein (RefSeq)	0.78	Shewana3_2541		alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen (RefSeq)	low	> 73
Pseudomonas fluorescens SBW25-INTG	0.12	PFLU_RS29195		heme biosynthesis protein HemY	0.68	PFLU_RS05705		peroxiredoxin	low	> 109
Pseudomonas fluorescens SBW25	0.12	PFLU_RS29195		heme biosynthesis protein HemY	0.68	PFLU_RS05705		peroxiredoxin	low	> 109
Shewanella loihica PV-4	0.12	Shew_0315		HemY domain-containing protein (RefSeq)	0.80	Shew_1516		alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (RefSeq)	—	—
Pseudomonas sp. RS175	0.12	PFR28_04363		Protein HemY	0.69	PFR28_03357		Alkyl hydroperoxide reductase C	low	> 88
Pseudomonas putida KT2440	0.12	PP_0189		putative heme biosynthesis protein	0.70	PP_1084		putative peroxiredoxin	low	> 96
Shewanella amazonensis SB2B	0.12	Sama_3257		HemY protein (RefSeq)	0.82	Sama_2094		alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen (RefSeq)	low	> 62

Not shown: 20 genomes with orthologs for HER17_RS01300 only; 11 genomes with orthologs for HER17_RS16005 only