Conservation of cofitness between HEPCGN_02880 and HEPCGN_08550 in Escherichia coli ECOR38

36 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 HEPCGN_08550 yacG DNA gyrase inhibitor YacG 0.64 5
Escherichia coli ECOR27 0.99 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NOLOHH_02915 yacG DNA gyrase inhibitor YacG — —
Escherichia coli BL21 0.99 ECD_01981 multidrug efflux system, subunit C 1.00 ECD_00101 DNA gyrase inhibitor — —
Escherichia coli ECRC62 0.99 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 BNILDI_08695 yacG DNA gyrase inhibitor YacG — —
Escherichia coli ECRC101 0.99 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_01085 yacG DNA gyrase inhibitor YacG — —
Escherichia coli ECRC100 0.99 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_10570 yacG DNA gyrase inhibitor YacG — —
Escherichia coli ECRC102 0.99 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_08420 yacG DNA gyrase inhibitor YacG — —
Escherichia coli ECRC99 0.99 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_17585 yacG DNA gyrase inhibitor YacG — —
Escherichia coli ECRC98 0.99 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 JDDGAC_14165 yacG DNA gyrase inhibitor YacG — —
Escherichia coli BW25113 0.99 b2076 mdtC multidrug efflux system, subunit C (NCBI) 1.00 b0101 yacG zinc-binding protein (NCBI) low > 76
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 0.99 ECOLIN_RS00545 DNA gyrase inhibitor YacG — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_03559 DNA gyrase inhibitor YacG — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 1.00 EFB2_03947 DNA gyrase inhibitor YacG — —
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.85 EX28DRAFT_3695 Uncharacterized protein conserved in bacteria — —
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.83 MPMX20_00793 DNA gyrase inhibitor YacG low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.68 GFF137 FIG003276: zinc-binding protein — —
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.84 BWI76_RS04810 DNA gyrase inhibitor YacG — —
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.77 IAI46_03495 DNA gyrase inhibitor YacG — —
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.64 HER17_RS03215 DNA gyrase inhibitor YacG low > 75
Pantoea sp. MT58 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC 0.77 IAI47_15880 DNA gyrase inhibitor YacG low > 76
Dickeya dianthicola 67-19 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC 0.66 HGI48_RS17925 DNA gyrase inhibitor YacG low > 71
Dickeya dadantii 3937 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC 0.69 DDA3937_RS17990 DNA gyrase inhibitor YacG low > 74
Dickeya dianthicola ME23 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC 0.66 DZA65_RS19070 DNA gyrase inhibitor YacG low > 75
Erwinia tracheiphila SCR3 0.73 LU632_RS08685 mdtC multidrug efflux RND transporter permease subunit MdtC 0.72 LU632_RS03005 yacG DNA gyrase inhibitor YacG low > 74
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit 0.47 ABZR87_RS01870 DNA gyrase inhibitor YacG low > 80
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_22900 acriflavine resistance protein B 0.53 AO353_14310 DNA gyrase inhibitor — —
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.50 OH686_16485 DNA gyrase inhibitor YacG — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.52 PFLU_RS03930 DNA gyrase inhibitor YacG 0.48 34
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.52 PFLU_RS03930 DNA gyrase inhibitor YacG low > 109
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.77 EX31_RS03550 DNA gyrase inhibitor YacG low > 89
Pseudomonas simiae WCS417 0.52 PS417_12750 acriflavine resistance protein B 0.52 PS417_03885 DNA gyrase inhibitor — —
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein 0.53 Pf6N2E2_5138 FIG003276: zinc-binding protein — —
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_25880 acriflavine resistance protein B 0.55 AO356_15995 DNA gyrase inhibitor — —
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS29845 efflux RND transporter permease subunit 0.45 QEN71_RS27330 DNA gyrase inhibitor YacG 0.29 88
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_06491 multidrug efflux pump 0.45 H281DRAFT_06252 hypothetical protein — —
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS07780 nodulation protein 0.45 BPHYT_RS17170 hypothetical protein low > 109
Acinetobacter radioresistens SK82 0.23 MPMX26_02516 Multidrug resistance protein MdtC 0.45 MPMX26_00298 DNA gyrase inhibitor YacG low > 36

Not shown: 27 genomes with orthologs for HEPCGN_02880 only; 5 genomes with orthologs for HEPCGN_08550 only