Conservation of cofitness between GFF2976 and GFF4533 in Sphingobium sp. HT1-2

26 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Sphingobium sp. HT1-2	1.0	GFF2976		RND efflux system, membrane fusion protein	1.0	GFF4533		Na+-driven multidrug efflux pump	0.74	8
Pseudomonas fluorescens FW300-N2E3	0.31	AO353_23965		RND transporter MFP subunit	0.23	AO353_23335		MATE family efflux transporter	low	> 101
Pseudomonas fluorescens FW300-N1B4	0.31	Pf1N1B4_4865		Multidrug efflux membrane fusion protein MexE	0.23	Pf1N1B4_4134		Na+ driven multidrug efflux pump	low	> 87
Pseudomonas sp. DMC3	0.31	GFF2877		Efflux pump periplasmic linker BepF	0.22	GFF1563		Multidrug export protein MepA	low	> 89
Pseudomonas segetis P6	0.31	MPMX49_02402		Efflux pump periplasmic linker BepF	0.16	MPMX49_01439		Multidrug resistance protein NorM	low	> 75
Pseudomonas fluorescens GW456-L13	0.30	PfGW456L13_3061		Multidrug efflux membrane fusion protein MexE	0.23	PfGW456L13_2743		Na+ driven multidrug efflux pump	low	> 87
Pseudomonas fluorescens SBW25-INTG	0.30	PFLU_RS14265		efflux RND transporter periplasmic adaptor subunit	0.23	PFLU_RS12410		MATE family efflux transporter	low	> 109
Pseudomonas fluorescens SBW25	0.30	PFLU_RS14265		efflux RND transporter periplasmic adaptor subunit	0.23	PFLU_RS12410		MATE family efflux transporter	low	> 109
Acinetobacter baumannii LAC-4	0.30	RR41_RS06070		multidrug efflux RND transporter periplasmic adaptor subunit AdeF	0.23	RR41_RS00520		MATE family efflux transporter	low	> 55
Ralstonia solanacearum GMI1000	0.30	RS_RS22485		MexE family multidrug efflux RND transporter periplasmic adaptor subunit	0.34	RS_RS17925		MATE family efflux transporter	low	> 80
Cupriavidus basilensis FW507-4G11	0.29	RR42_RS27680		MexE family multidrug efflux RND transporter periplasmic adaptor subunit	0.47	RR42_RS34880		multidrug transporter MatE	low	> 128
Pseudomonas simiae WCS417	0.29	PS417_13195		RND transporter MFP subunit	0.23	PS417_11670		multidrug transporter MATE	low	> 88
Pseudomonas lactucae CFBP13502	0.29	GEMAOFIL_03222		Efflux pump periplasmic linker BepF	0.22	GEMAOFIL_02586		Multidrug export protein MepA	low	> 96
Pseudomonas sp. RS175	0.29	PFR28_01729		Efflux pump periplasmic linker BepF	0.22	PFR28_02508		Multidrug export protein MepA	low	> 88
Pseudomonas fluorescens FW300-N2E2	0.29	Pf6N2E2_825		Multidrug efflux membrane fusion protein MexE	0.22	Pf6N2E2_422		Na+ driven multidrug efflux pump	low	> 103
Pseudomonas orientalis W4I3	0.29	QF045_RS16755		efflux RND transporter periplasmic adaptor subunit	0.23	QF045_RS13765		MATE family efflux transporter	low	> 93
Xanthomonas campestris pv. campestris strain 8004	0.28	Xcc-8004.3478.1		RND efflux system, membrane fusion protein CmeA	0.41	Xcc-8004.3764.1		Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog	low	> 74
Lysobacter sp. OAE881	0.28	ABIE51_RS01055		efflux RND transporter periplasmic adaptor subunit	0.43	ABIE51_RS07765		MATE family efflux transporter	low	> 62
Dyella japonica UNC79MFTsu3.2	0.28	ABZR86_RS15405		efflux RND transporter periplasmic adaptor subunit	0.45	ABZR86_RS14750		MATE family efflux transporter	low	> 74
Variovorax sp. SCN45	0.27	GFF430		RND efflux system, membrane fusion protein	0.24	GFF1403		MATE efflux family protein	low	> 127
Acidovorax sp. GW101-3H11	0.27	Ac3H11_259		Probable Co/Zn/Cd efflux system membrane fusion protein	0.18	Ac3H11_4355		Na+ driven multidrug efflux pump	low	> 79
Agrobacterium fabrum C58	0.25	Atu2482		HlyD family secretion protein	0.06	Atu3669		siderophore biosynthesis protein	low	> 89
Rhodospirillum rubrum S1H	0.25	Rru_A0887		Secretion protein HlyD (NCBI)	0.07	Rru_A0678		Multi antimicrobial extrusion protein MatE (NCBI)	low	> 58
Pontibacter actiniarum KMM 6156, DSM 19842	0.23	CA264_03650		MexE family multidrug efflux RND transporter periplasmic adaptor subunit	0.12	CA264_21515		MATE family efflux transporter	low	> 74
Bacteroides stercoris CC31F	0.21	HMPREF1181_RS14285		efflux RND transporter periplasmic adaptor subunit	0.15	HMPREF1181_RS16845		MATE family efflux transporter	low	> 56
Phocaeicola vulgatus CL09T03C04	0.20	HMPREF1058_RS05165		efflux RND transporter periplasmic adaptor subunit	0.16	HMPREF1058_RS16270		MATE family efflux transporter	low	> 67
Phocaeicola dorei CL03T12C01	0.20	ABI39_RS18720		efflux RND transporter periplasmic adaptor subunit	0.16	ABI39_RS12160		MATE family efflux transporter	low	> 72

Not shown: 41 genomes with orthologs for GFF2976 only; 16 genomes with orthologs for GFF4533 only