Conservation of cofitness between ECD_00288 and ECD_02140 in Escherichia coli BL21

32 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00288 2-methylcitrate dehydratase 1.0 ECD_02140 fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase low > 61
Escherichia coli BW25113 1.00 b0334 prpD 2-methylcitrate dehydratase (NCBI) 0.99 b2213 ada fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03337 2-methylcitrate dehydratase 0.99 OHPLBJKB_01497 Bifunctional transcriptional activator/DNA repair enzyme Ada low > 73
Escherichia coli ECOR27 1.00 NOLOHH_01765 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 NOLOHH_14785 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 75
Escherichia fergusonii Becca 1.00 EFB2_03704 2-methylcitrate dehydratase 0.97 EFB2_01642 Bifunctional transcriptional activator/DNA repair enzyme Ada low > 86
Escherichia coli ECRC62 1.00 BNILDI_23180 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 BNILDI_13705 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 75
Escherichia coli ECRC100 0.99 OKFHMN_08890 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 OKFHMN_23210 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 80
Escherichia coli ECRC99 0.99 KEDOAH_19075 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 KEDOAH_04975 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada — —
Escherichia coli ECRC101 0.99 MCAODC_28120 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 MCAODC_14260 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02160 2-methylcitrate dehydratase 0.97 ECOLIN_RS12925 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada — —
Escherichia coli ECRC98 0.99 JDDGAC_12545 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 JDDGAC_27170 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 86
Escherichia coli ECRC102 0.99 NIAGMN_06945 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 NIAGMN_20975 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada — —
Escherichia coli ECOR38 0.99 HEPCGN_07475 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 HEPCGN_22475 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF4265 2-methylcitrate dehydratase (EC 4.2.1.79) 0.74 GFF1827 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) low > 78
Paraburkholderia graminis OAS925 0.82 ABIE53_004759 2-methylcitrate dehydratase 0.41 ABIE53_000315 AraC family transcriptional regulator of adaptative response/methylated-DNA-[protein]-cysteine methyltransferase low > 113
Paraburkholderia sabiae LMG 24235 0.82 QEN71_RS17540 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.44 QEN71_RS29610 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 153
Paraburkholderia bryophila 376MFSha3.1 0.82 H281DRAFT_06607 2-methylcitrate dehydratase 0.41 H281DRAFT_02337 AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase — —
Burkholderia phytofirmans PsJN 0.81 BPHYT_RS33975 2-methylcitrate dehydratase 0.40 BPHYT_RS19690 AraC family transcriptional regulator low > 109
Ralstonia solanacearum GMI1000 0.79 RS_RS10060 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.50 RS_RS12885 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 80
Ralstonia solanacearum PSI07 0.79 RPSI07_RS14630 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.51 RPSI07_RS12035 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 81
Ralstonia solanacearum UW163 0.78 UW163_RS11040 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.48 UW163_RS08360 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada — —
Ralstonia solanacearum IBSBF1503 0.78 RALBFv3_RS02685 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.48 RALBFv3_RS05265 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada 0.44 19
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_00880 2-methylcitrate dehydratase 0.48 AO353_27015 6-O-methylguanine DNA methyltransferase low > 101
Pseudomonas fluorescens GW456-L13 0.61 PfGW456L13_4114 2-methylcitrate dehydratase (EC 4.2.1.79) 0.49 PfGW456L13_2914 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) low > 87
Pseudomonas fluorescens FW300-N1B4 0.60 Pf1N1B4_3823 2-methylcitrate dehydratase (EC 4.2.1.79) 0.50 Pf1N1B4_5024 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) low > 87
Pseudomonas fluorescens SBW25 0.60 PFLU_RS22670 2-methylcitrate dehydratase 0.49 PFLU_RS14505 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 109
Pseudomonas fluorescens SBW25-INTG 0.60 PFLU_RS22670 2-methylcitrate dehydratase 0.49 PFLU_RS14505 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 109
Pseudomonas simiae WCS417 0.60 PS417_21060 2-methylcitrate dehydratase 0.49 PS417_14105 6-O-methylguanine DNA methyltransferase low > 88
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS00675 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.49 LRK54_RS18115 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 59
Rhodanobacter denitrificans MT42 0.59 LRK55_RS00450 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.50 LRK55_RS17970 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 63
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_06580 prpD bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.52 OKGIIK_07195 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 52
Pseudomonas putida KT2440 0.58 PP_2338 2-methylcitrate dehydratase 0.51 PP_0706 fused O(6)-alkylguanine DNA alkyltransferase - transcriptional activator low > 96
Rahnella sp. WP5 0.46 EX31_RS11170 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.50 EX31_RS21655 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada low > 89

Not shown: 7 genomes with orthologs for ECD_00288 only; 21 genomes with orthologs for ECD_02140 only