| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05290 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 1.0 | CSW01_13470 | | transcriptional regulator | 0.64 | 17 |
| Rahnella sp. WP5 | 0.70 | EX31_RS09915 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.36 | EX31_RS23790 | | transcriptional regulator | low | > 89 |
| Shewanella amazonensis SB2B | 0.69 | Sama_0766 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | 0.49 | Sama_2786 | | putative transcriptional regulator (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.69 | Shewana3_3274 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | 0.47 | Shewana3_3176 | | transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.68 | Shew_0718 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | 0.50 | Shew_0915 | | putative transcriptional regulator (RefSeq) | — | — |
| Serratia liquefaciens MT49 | 0.67 | IAI46_13990 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.45 | IAI46_24615 | | HTH domain-containing protein | low | > 87 |
| Shewanella oneidensis MR-1 | 0.67 | SO1039 | cobO | cob(I)alamin adenosyltransferase (NCBI ptt file) | 0.47 | SO3584 | | conserved hypothetical protein (NCBI ptt file) | low | > 76 |
| Cupriavidus basilensis FW507-4G11 | 0.52 | RR42_RS16125 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.40 | RR42_RS27660 | | transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.51 | AO353_02640 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.39 | AO353_17750 | | transcriptional regulator | low | > 101 |
| Pseudomonas sp. SVBP6 | 0.48 | COO64_RS07250 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.41 | COO64_RS10740 | | metalloregulator ArsR/SmtB family transcription factor | low | > 93 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS10920 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.39 | ABZR86_RS09450 | | winged helix-turn-helix transcriptional regulator | low | > 74 |
| Rhizobium sp. OAE497 | 0.41 | ABIE40_RS11150 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.36 | ABIE40_RS04555 | | MarR family transcriptional regulator | low | > 107 |
| Synechococcus elongatus PCC 7942 | 0.40 | Synpcc7942_0957 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.26 | Synpcc7942_1733 | sufR | transcriptional regulator | — | — |
| Herbaspirillum seropedicae SmR1 | 0.39 | HSERO_RS13260 | | cobinamide adenolsyltransferase | 0.38 | HSERO_RS06885 | | transcriptional regulator | — | — |
| Synechocystis sp000284455 PCC 6803 | 0.39 | SGL_RS08905 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.29 | SGL_RS15245 | | iron-sulfur cluster biosynthesis transcriptional regulator SufR | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.34 | GFF3983 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.37 | GFF5265 | | hypothetical protein | low | > 90 |
| Variovorax sp. SCN45 | 0.33 | GFF444 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) @ Cob(I)alamin adenosyltransferase (EC 2.5.1.17), clustered with cobalamin synthesis | 0.41 | GFF3507 | | Transcriptional regulator, DeoR family | low | > 127 |
| Variovorax sp. OAS795 | 0.32 | ABID97_RS17395 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.40 | ABID97_RS01035 | | metalloregulator ArsR/SmtB family transcription factor | low | > 91 |
Not shown: 78 genomes with orthologs for CSW01_05290 only; 0 genomes with orthologs for CSW01_13470 only