Conservation of cofitness between CSW01_13830 and CSW01_01465 in Vibrio cholerae E7946 ATCC 55056

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13830 YihY/virulence factor BrkB family protein 1.0 CSW01_01465 ketohydroxyglutarate aldolase 0.42 12
Shewanella oneidensis MR-1 0.51 SO4401 rbn ribonuclease BN (NCBI ptt file) 0.44 SO2486 eda 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI ptt file) — —
Shewanella loihica PV-4 0.49 Shew_3545 rbn ribonuclease BN (RefSeq) 0.43 Shew_2045 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) — —
Shewanella amazonensis SB2B 0.45 Sama_3404 rbn ribonuclease BN (RefSeq) 0.42 Sama_1809 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) — —
Serratia liquefaciens MT49 0.44 IAI46_24935 virulence factor BrkB family protein 0.44 IAI46_23180 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 87
Alteromonas macleodii MIT1002 0.44 MIT1002_03671 ribonuclease BN/unknown domain fusion protein 0.42 MIT1002_02403 KHG/KDPG aldolase — —
Enterobacter sp. TBS_079 0.43 MPMX20_04583 hypothetical protein 0.44 MPMX20_02755 KHG/KDPG aldolase low > 85
Enterobacter asburiae PDN3 0.43 EX28DRAFT_4368 Predicted membrane protein 0.44 EX28DRAFT_0706 Entner-Doudoroff aldolase low > 76
Klebsiella pneumoniae MKP103 0.42 KDGMDA_09030 virulence factor BrkB family protein 0.38 KDGMDA_25360 keto-deoxy-phosphogluconate aldolase low > 95
Pantoea agglomerans CFBP13505 P0401 0.42 PagCFBP13505_RS18870 virulence factor BrkB family protein 0.44 PagCFBP13505_RS02380 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 74
Klebsiella michiganensis M5al 0.41 BWI76_RS00420 hypothetical protein 0.38 BWI76_RS18095 ketohydroxyglutarate aldolase — —
Rahnella sp. WP5 0.41 EX31_RS15855 virulence factor BrkB family protein 0.43 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 89
Pantoea sp. MT58 0.41 IAI47_00475 virulence factor BrkB family protein 0.44 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 76
Escherichia coli ECRC99 0.41 KEDOAH_14150 yihY virulence factor BrkB family protein 0.40 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase — —
Escherichia coli ECOR38 0.41 HEPCGN_12640 yihY virulence factor BrkB family protein 0.40 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 88
Escherichia coli ECRC102 0.41 NIAGMN_11760 yihY virulence factor BrkB family protein 0.40 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase — —
Escherichia coli ECRC100 0.41 OKFHMN_14005 yihY virulence factor BrkB family protein 0.40 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 79
Escherichia coli BL21 0.41 ECD_03771 BrkB family putative transporter, inner membrane protein 0.40 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase — —
Escherichia coli ECRC62 0.41 BNILDI_05390 yihY virulence factor BrkB family protein 0.40 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 75
Escherichia coli Nissle 1917 0.41 ECOLIN_RS22380 virulence factor BrkB family protein 0.40 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase — —
Escherichia coli ECRC101 0.41 MCAODC_04505 yihY virulence factor BrkB family protein 0.40 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 87
Escherichia fergusonii Becca 0.41 EFB2_04732 hypothetical protein 0.40 EFB2_02093 KHG/KDPG aldolase low > 86
Escherichia coli ECRC98 0.41 JDDGAC_17630 yihY virulence factor BrkB family protein 0.40 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.41 GFF2241 Inner membrane protein YihY, formerly thought to be RNase BN 0.42 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) low > 78
Escherichia coli BW25113 0.41 b3886 rbn ribonuclease BN (NCBI) 0.40 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.41 OHPLBJKB_04168 hypothetical protein 0.40 OHPLBJKB_01879 KHG/KDPG aldolase low > 74
Escherichia coli ECOR27 0.40 NOLOHH_06140 yihY virulence factor BrkB family protein 0.39 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 76
Erwinia tracheiphila SCR3 0.39 LU632_RS22160 virulence factor BrkB family protein 0.39 LU632_RS13355 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase low > 73
Erwinia tracheiphila HP pepo 2.2 0.39 IJEDHG_08310 virulence factor BrkB family protein 0.39 IJEDHG_22200 eda keto-deoxy-phosphogluconate aldolase low > 61
Variovorax sp. OAS795 0.26 ABID97_RS28975 YihY family inner membrane protein 0.38 ABID97_RS21295 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase — —
Methylophilus sp. DMC18 0.13 GFF518 hypothetical protein 0.32 GFF286 KHG/KDPG aldolase — —
Sphingobium sp. HT1-2 0.09 GFF1875 Ribonuclease BN 0.37 GFF1595 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) — —
Pseudomonas fluorescens FW300-N1B4 0.09 Pf1N1B4_569 Ribonuclease BN (EC 3.1.-.-) 0.36 Pf1N1B4_587 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.09 Echvi_3363 Predicted membrane protein 0.20 Echvi_3630 Entner-Doudoroff aldolase low > 79
Pseudomonas fluorescens FW300-N2E3 0.09 AO353_03295 ribonuclease BN 0.35 AO353_03350 keto-deoxy-phosphogluconate aldolase — —
Pseudomonas fluorescens GW456-L13 0.08 PfGW456L13_1913 Ribonuclease BN (EC 3.1.-.-) 0.35 PfGW456L13_1903 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) — —

Not shown: 3 genomes with orthologs for CSW01_13830 only; 72 genomes with orthologs for CSW01_01465 only