Conservation of cofitness between b4238 and b4053 in Escherichia coli BW25113

31 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4238 nrdD anaerobic ribonucleoside triphosphate reductase (NCBI) 1.0 b4053 alr alanine racemase (NCBI) 0.66 2
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03797 Anaerobic ribonucleoside-triphosphate reductase 1.00 OHPLBJKB_03990 Alanine racemase, biosynthetic low > 73
Escherichia coli ECOR38 1.00 HEPCGN_10100 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 HEPCGN_11540 alr alanine racemase low > 85
Escherichia coli ECRC62 1.00 BNILDI_07340 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 BNILDI_06350 alr alanine racemase — —
Escherichia coli BL21 1.00 ECD_04106 anaerobic ribonucleoside-triphosphate reductase 1.00 ECD_03925 alanine racemase, biosynthetic, PLP-binding low > 60
Escherichia coli ECOR27 1.00 NOLOHH_04170 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 NOLOHH_05175 alr alanine racemase low > 57
Escherichia coli ECRC101 1.00 MCAODC_02410 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 MCAODC_03435 alr alanine racemase — —
Escherichia coli ECRC98 1.00 JDDGAC_15545 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 JDDGAC_16560 alr alanine racemase — —
Escherichia coli ECRC102 1.00 NIAGMN_09755 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 NIAGMN_10770 alr alanine racemase — —
Escherichia coli ECRC101 1.00 OKFHMN_11905 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 OKFHMN_12925 alr alanine racemase — —
Escherichia coli ECRC99 1.00 KEDOAH_16250 nrdD anaerobic ribonucleoside-triphosphate reductase 1.00 KEDOAH_15225 alr alanine racemase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS24585 anaerobic ribonucleoside-triphosphate reductase 0.94 ECOLIN_RS23405 alanine racemase low > 52
Escherichia fergusonii Becca 1.00 EFB2_04295 Anaerobic ribonucleoside-triphosphate reductase 1.00 EFB2_04547 Alanine racemase, biosynthetic low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF919 Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) 0.92 GFF1422 Alanine racemase (EC 5.1.1.1) low > 78
Klebsiella michiganensis M5al 0.95 BWI76_RS02935 anaerobic ribonucleoside triphosphate reductase 0.91 BWI76_RS01920 alanine racemase low > 92
Enterobacter sp. TBS_079 0.95 MPMX20_00531 Anaerobic ribonucleoside-triphosphate reductase 0.90 MPMX20_00269 Alanine racemase, biosynthetic low > 85
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3437 ribonucleoside-triphosphate reductase class III catalytic subunit (EC 1.17.4.2) 0.90 EX28DRAFT_4259 alanine racemase low > 76
Dickeya dianthicola ME23 0.88 DZA65_RS01880 anaerobic ribonucleoside-triphosphate reductase 0.68 DZA65_RS18650 alanine racemase 0.49 28
Dickeya dianthicola 67-19 0.88 HGI48_RS01825 anaerobic ribonucleoside-triphosphate reductase 0.67 HGI48_RS17565 alanine racemase low > 71
Dickeya dadantii 3937 0.88 DDA3937_RS01875 anaerobic ribonucleoside-triphosphate reductase 0.68 DDA3937_RS17510 alanine racemase — —
Pectobacterium carotovorum WPP14 0.87 HER17_RS19525 anaerobic ribonucleoside-triphosphate reductase 0.72 HER17_RS03655 alanine racemase low > 75
Serratia liquefaciens MT49 0.87 IAI46_02135 anaerobic ribonucleoside-triphosphate reductase 0.74 IAI46_22945 alanine racemase low > 86
Rahnella sp. WP5 0.87 EX31_RS08395 anaerobic ribonucleoside-triphosphate reductase 0.72 EX31_RS11885 alanine racemase low > 89
Shewanella oneidensis MR-1 0.80 SO2834 nrdD anaerobic ribonucleoside-triphosphate reductase (NCBI ptt file) 0.56 SO3916 alr alanine racemase, biosynthetic (NCBI ptt file) — —
Shewanella sp. ANA-3 0.79 Shewana3_2603 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.55 Shewana3_0714 alr alanine racemase (RefSeq) — —
Shewanella loihica PV-4 0.78 Shew_2449 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.55 Shew_3277 alr alanine racemase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_16800 anaerobic ribonucleoside-triphosphate reductase 0.61 CSW01_01955 alanine racemase — —
Shewanella amazonensis SB2B 0.77 Sama_1275 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.57 Sama_3057 alr alanine racemase (RefSeq) — —
Bifidobacterium breve UCC2003 0.43 BBR_RS17915 anaerobic ribonucleoside-triphosphate reductase 0.16 BBR_RS13170 alanine racemase — —
Desulfovibrio vulgaris Miyazaki F 0.09 DvMF_1473 anaerobic ribonucleoside triphosphate reductase (RefSeq) 0.24 DvMF_1349 alanine racemase (RefSeq) low > 51
Kangiella aquimarina DSM 16071 0.09 B158DRAFT_1727 ribonucleoside-triphosphate reductase class III catalytic subunit (EC 1.17.4.2) 0.46 B158DRAFT_2013 alanine racemase low > 40
Pseudomonas stutzeri RCH2 0.08 Psest_0840 anaerobic ribonucleoside-triphosphate reductase 0.38 Psest_0699 alanine racemase — —

Not shown: 24 genomes with orthologs for b4238 only; 20 genomes with orthologs for b4053 only