Conservation of cofitness between b1768 and b3125 in Escherichia coli BW25113

33 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1768 ydjB orf, hypothetical protein (VIMSS) 1.0 b3125 garR tartronate semialdehyde reductase (RefSeq) 0.19 11
Escherichia coli BL21 1.00 ECD_01737 nicotinamidase/pyrazinamidase 1.00 ECD_02990 tartronate semialdehyde reductase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01964 Nicotinamidase 1.00 OHPLBJKB_00578 2-hydroxy-3-oxopropionate reductase low > 73
Escherichia coli ECRC101 1.00 OKFHMN_26800 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 OKFHMN_18370 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECRC102 1.00 NIAGMN_01265 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 NIAGMN_16130 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECRC99 1.00 KEDOAH_01310 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 KEDOAH_09780 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECRC101 0.99 MCAODC_18610 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 MCAODC_08880 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECRC98 0.99 JDDGAC_01375 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 JDDGAC_22000 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECOR27 0.99 NOLOHH_17315 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 NOLOHH_10150 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli ECOR38 0.99 HEPCGN_05175 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 HEPCGN_17205 garR 2-hydroxy-3-oxopropionate reductase low > 85
Escherichia coli ECRC62 0.98 BNILDI_16100 pncA bifunctional nicotinamidase/pyrazinamidase 1.00 BNILDI_01380 garR 2-hydroxy-3-oxopropionate reductase — —
Escherichia coli Nissle 1917 0.97 ECOLIN_RS09865 bifunctional nicotinamidase/pyrazinamidase 1.00 ECOLIN_RS17960 2-hydroxy-3-oxopropionate reductase — —
Escherichia fergusonii Becca 0.97 EFB2_02226 Nicotinamidase 0.99 EFB2_00694 2-hydroxy-3-oxopropionate reductase low > 86
Enterobacter asburiae PDN3 0.85 EX28DRAFT_1769 Amidases related to nicotinamidase 0.91 EX28DRAFT_3182 2-hydroxy-3-oxopropionate reductase low > 76
Enterobacter sp. TBS_079 0.85 MPMX20_01848 Nicotinamidase 0.93 MPMX20_04033 2-hydroxy-3-oxopropionate reductase low > 85
Klebsiella michiganensis M5al 0.84 BWI76_RS11575 nicotinamidase/pyrazinamidase 0.95 BWI76_RS24825 2-hydroxy-3-oxopropionate reductase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.82 GFF3481 Nicotinamidase (EC 3.5.1.19) 0.98 GFF1536 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) low > 78
Rahnella sp. WP5 0.58 EX31_RS06295 bifunctional nicotinamidase/pyrazinamidase 0.84 EX31_RS07980 2-hydroxy-3-oxopropionate reductase low > 89
Dickeya dadantii 3937 0.58 DDA3937_RS10280 bifunctional nicotinamidase/pyrazinamidase 0.85 DDA3937_RS17035 2-hydroxy-3-oxopropionate reductase low > 74
Dickeya dianthicola 67-19 0.57 HGI48_RS10290 bifunctional nicotinamidase/pyrazinamidase 0.86 HGI48_RS17090 2-hydroxy-3-oxopropionate reductase low > 71
Dickeya dianthicola ME23 0.57 DZA65_RS10765 bifunctional nicotinamidase/pyrazinamidase 0.86 DZA65_RS18165 2-hydroxy-3-oxopropionate reductase low > 75
Pantoea sp. MT58 0.56 IAI47_08960 bifunctional nicotinamidase/pyrazinamidase 0.84 IAI47_04100 2-hydroxy-3-oxopropionate reductase low > 76
Erwinia tracheiphila SCR3 0.56 LU632_RS12980 pncA bifunctional nicotinamidase/pyrazinamidase 0.88 LU632_RS06330 garR 2-hydroxy-3-oxopropionate reductase low > 74
Pectobacterium carotovorum WPP14 0.56 HER17_RS11115 bifunctional nicotinamidase/pyrazinamidase 0.84 HER17_RS04095 2-hydroxy-3-oxopropionate reductase low > 75
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_17740 nicotinamidase/pyrazinamidase 0.31 CSW01_14090 NAD(P)-dependent oxidoreductase low > 62
Rhodospirillum rubrum S1H 0.37 Rru_A3002 Nicotinamidase (NCBI) 0.20 Rru_A1833 3-hydroxyisobutyrate dehydrogenase (NCBI) low > 58
Phaeobacter inhibens DSM 17395 0.36 PGA1_c32150 pyrazinamidase/nicotinamidase 0.26 PGA1_c14880 putative 3-hydroxyisobutyrate dehydrogenase low > 62
Rhodanobacter sp. FW510-T8 0.35 OKGIIK_00440 pncA bifunctional nicotinamidase/pyrazinamidase 0.19 OKGIIK_03510 mmsB 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase low > 52
Dyella japonica UNC79MFTsu3.2 0.34 ABZR86_RS18095 bifunctional nicotinamidase/pyrazinamidase 0.24 ABZR86_RS00420 NAD(P)-dependent oxidoreductase low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS09310 bifunctional nicotinamidase/pyrazinamidase 0.23 A4249_RS06070 NAD(P)-dependent oxidoreductase low > 48
Acinetobacter radioresistens SK82 0.34 MPMX26_02980 Nicotinamidase 0.28 MPMX26_01549 3-hydroxyisobutyrate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.34 LRK54_RS06180 bifunctional nicotinamidase/pyrazinamidase 0.19 LRK54_RS14685 NAD(P)-dependent oxidoreductase low > 59
Rhodanobacter denitrificans MT42 0.34 LRK55_RS05925 bifunctional nicotinamidase/pyrazinamidase 0.19 LRK55_RS14400 NAD(P)-dependent oxidoreductase low > 63
Mycobacterium tuberculosis H37Rv 0.24 Rv2043c Pyrazinamidase/nicotinamidase PncA (PZase) 0.22 Rv0751c Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh) low > 58

Not shown: 25 genomes with orthologs for b1768 only; 11 genomes with orthologs for b3125 only