Conservation of cofitness between JDDGAC_28300 and JDDGAC_13665 in Escherichia coli ECRC98

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC98 1.0 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 JDDGAC_13665 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO 0.58 14
Escherichia coli ECRC101 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_00585 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_18085 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO — —
Escherichia coli ECRC102 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_07920 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO — —
Escherichia coli ECRC100 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_10070 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 80
Escherichia coli ECOR27 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NOLOHH_02415 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 75
Escherichia coli BL21 1.00 ECD_01981 multidrug efflux system, subunit C 0.99 ECD_00194 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase, SAM-dependent low > 61
Escherichia coli ECRC62 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 0.99 BNILDI_09255 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 75
Escherichia coli BW25113 0.99 b2076 mdtC multidrug efflux system, subunit C (NCBI) 1.00 b0195 yaeB hypothetical protein (NCBI) 0.18 10
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_03466 tRNA (adenine(37)-N6)-methyltransferase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 0.99 HEPCGN_08010 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 0.99 ECOLIN_RS01075 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 0.98 EFB2_03848 tRNA (adenine(37)-N6)-methyltransferase low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.85 EX28DRAFT_3783 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.84 MPMX20_00879 tRNA (adenine(37)-N6)-methyltransferase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.89 GFF25 COG1720: Uncharacterized conserved protein low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.85 BWI76_RS05345 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 92
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.74 IAI46_20095 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 86
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.71 HER17_RS04360 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 75
Pantoea sp. MT58 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC 0.70 IAI47_15405 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 76
Dickeya dianthicola 67-19 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC 0.70 HGI48_RS16935 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 71
Dickeya dadantii 3937 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC 0.72 DDA3937_RS16865 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 74
Dickeya dianthicola ME23 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC 0.70 DZA65_RS18010 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 75
Erwinia tracheiphila SCR3 0.73 LU632_RS08685 mdtC multidrug efflux RND transporter permease subunit MdtC 0.69 LU632_RS19840 tsaA tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 74
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_22900 acriflavine resistance protein B 0.41 AO353_16855 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA low > 101
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.39 OH686_18830 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA low > 80
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein 0.39 PfGW456L13_4658 COG1720: Uncharacterized conserved protein low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.53 Psyr_2484 Acriflavin resistance protein 0.39 Psyr_1388 Protein of unknown function UPF0066 low > 86
Pseudomonas syringae pv. syringae B728a 0.53 Psyr_2484 Acriflavin resistance protein 0.39 Psyr_1388 Protein of unknown function UPF0066 low > 86
Pseudomonas stutzeri RCH2 0.53 Psest_2140 Cation/multidrug efflux pump 0.39 Psest_2637 putative methyltransferase, YaeB/AF_0241 family low > 67
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.39 PFLU_RS05930 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 109
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.39 PFLU_RS05930 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 109
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.71 EX31_RS12900 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO low > 89
Pseudomonas putida KT2440 0.52 PP_3583 multidrug efflux transport system - membrane subunit 0.39 PP_1189 conserved hypothetical protein low > 96
Pseudomonas simiae WCS417 0.52 PS417_12750 acriflavine resistance protein B 0.38 PS417_05860 hypothetical protein low > 88
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein 0.36 Pf6N2E2_2982 COG1720: Uncharacterized conserved protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_25880 acriflavine resistance protein B 0.40 AO356_05620 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA low > 104
Pseudomonas sp. RS175 0.51 PFR28_02193 Multidrug resistance protein MdtC 0.39 PFR28_00482 tRNA (adenine(37)-N6)-methyltransferase low > 88
Acinetobacter radioresistens SK82 0.23 MPMX26_02516 Multidrug resistance protein MdtC 0.36 MPMX26_02038 tRNA (adenine(37)-N6)-methyltransferase low > 36

Not shown: 25 genomes with orthologs for JDDGAC_28300 only; 8 genomes with orthologs for JDDGAC_13665 only