Conservation of cofitness between JDDGAC_28300 and JDDGAC_11300 in Escherichia coli ECRC98

32 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC98 1.0 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 JDDGAC_11300 ybdK YbdK family carboxylate-amine ligase 0.62 5
Escherichia coli ECRC99 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_20315 ybdK YbdK family carboxylate-amine ligase — —
Escherichia coli ECRC101 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_26870 ybdK YbdK family carboxylate-amine ligase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_05710 ybdK YbdK family carboxylate-amine ligase — —
Escherichia coli ECRC100 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_07655 ybdK YbdK family carboxylate-amine ligase low > 80
Escherichia coli ECOR27 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 0.99 NOLOHH_24035 ybdK YbdK family carboxylate-amine ligase low > 75
Escherichia coli BL21 1.00 ECD_01981 multidrug efflux system, subunit C 0.99 ECD_00542 weak gamma-glutamyl:cysteine ligase low > 61
Escherichia coli ECRC62 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 0.99 BNILDI_22045 ybdK YbdK family carboxylate-amine ligase low > 75
Escherichia coli BW25113 0.99 b2076 mdtC multidrug efflux system, subunit C (NCBI) 0.99 b0581 ybdK gamma-glutamyl:cysteine ligase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01628 Multidrug resistance protein MdtC 0.99 OHPLBJKB_03128 Putative glutamate--cysteine ligase 2 low > 73
Escherichia coli ECOR38 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 0.99 HEPCGN_00635 ybdK YbdK family carboxylate-amine ligase low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 0.98 ECOLIN_RS03175 YbdK family carboxylate-amine ligase — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 0.98 EFB2_03513 Putative glutamate--cysteine ligase 2 low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.78 EX28DRAFT_2417 carboxylate-amine ligase, YbdK family low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.78 MPMX20_01143 Putative glutamate--cysteine ligase 2 low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.86 GFF4487 FIG00638355: hypothetical protein low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.74 BWI76_RS07515 glutamate--cysteine ligase low > 92
Ralstonia solanacearum PSI07 0.63 RPSI07_RS05520 nodulation protein 0.45 RPSI07_RS08555 glutamate--cysteine ligase low > 81
Ralstonia solanacearum GMI1000 0.63 RS_RS22920 nodulation protein 0.45 RS_RS16525 glutamate--cysteine ligase low > 80
Ralstonia solanacearum UW163 0.63 UW163_RS21015 nodulation protein 0.45 UW163_RS04900 glutamate--cysteine ligase — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS18115 nodulation protein 0.45 RALBFv3_RS08710 glutamate--cysteine ligase low > 76
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit 0.43 ABZR87_RS03955 YbdK family carboxylate-amine ligase low > 80
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS07655 nodulation protein 0.39 HSERO_RS04340 gamma-glutamyl ligase low > 78
Acidovorax sp. GW101-3H11 0.56 Ac3H11_3620 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.44 Ac3H11_753 FIG074102: hypothetical protein — —
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.12 OH686_01215 hypothetical protein low > 80
Pseudomonas putida KT2440 0.52 PP_3583 multidrug efflux transport system - membrane subunit 0.10 PP_3253 Carboxylate-amine ligase PP_3253 low > 96
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS29845 efflux RND transporter permease subunit 0.46 QEN71_RS29475 YbdK family carboxylate-amine ligase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein 0.40 GFF358 FIG074102: hypothetical protein low > 90
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_06491 multidrug efflux pump 0.44 H281DRAFT_02362 carboxylate-amine ligase low > 103
Azospirillum brasilense Sp245 0.44 AZOBR_RS14670 multidrug transporter 0.18 AZOBR_RS11345 carboxylate-amine ligase low > 97
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS07780 nodulation protein 0.44 BPHYT_RS19565 gamma-glutamyl:cysteine ligase 0.32 30
Bosea sp. OAE506 0.41 ABIE41_RS20140 efflux RND transporter permease subunit 0.14 ABIE41_RS23095 carboxylate-amine ligase low > 77
Variovorax sp. OAS795 0.39 ABID97_RS06490 efflux RND transporter permease subunit 0.41 ABID97_RS04885 YbdK family carboxylate-amine ligase low > 91

Not shown: 31 genomes with orthologs for JDDGAC_28300 only; 9 genomes with orthologs for JDDGAC_11300 only