Conservation of cofitness between HER17_RS16865 and HER17_RS07420 in Pectobacterium carotovorum WPP14

19 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Pectobacterium carotovorum WPP14	1.0	HER17_RS16865		NAD(P)H-dependent oxidoreductase	1.0	HER17_RS07420		SMR family transporter	0.46	17
Pseudomonas fluorescens FW300-N2E3	0.59	AO353_26030		NAD(P)H dehydrogenase	0.44	AO353_12990		multidrug DMT transporter	low	> 101
Rhodospirillum rubrum S1H	0.57	Rru_A3066		NAD(P)H dehydrogenase (quinone) (NCBI)	0.36	Rru_A3353		Small multidrug resistance protein (NCBI)	low	> 58
Xanthomonas campestris pv. campestris strain 8004	0.57	Xcc-8004.74.1		NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) @ Putative NADPH-quinone reductase (modulator of drug activity B) @ Flavodoxin 2	0.49	Xcc-8004.2118.1		Ethidium bromide-methyl viologen resistance protein EmrE	low	> 74
Pseudomonas fluorescens FW300-N2C3	0.57	AO356_26190		NAD(P)H dehydrogenase	0.44	AO356_08830		multidrug DMT transporter	low	> 104
Pseudomonas fluorescens FW300-N2E2	0.57	Pf6N2E2_1112		NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) @ Putative NADPH-quinone reductase (modulator of drug activity B) @ Flavodoxin 2	0.43	Pf6N2E2_3648		Ethidium bromide-methyl viologen resistance protein EmrE	—	—
Pseudomonas sp. RS175	0.55	PFR28_01850		Glutathione-regulated potassium-efflux system ancillary protein KefF	0.43	PFR28_05087		Multidrug transporter	low	> 88
Hydrogenophaga sp. GW460-11-11-14-LB1	0.54	GFF3563		NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) @ Putative NADPH-quinone reductase (modulator of drug activity B) @ Flavodoxin 2	0.52	GFF4245		Ethidium bromide-methyl viologen resistance protein EmrE	low	> 90
Pseudomonas fluorescens SBW25	0.53	PFLU_RS13525		NAD(P)H-dependent oxidoreductase	0.41	PFLU_RS02410		multidrug efflux SMR transporter	low	> 109
Pseudomonas fluorescens SBW25-INTG	0.53	PFLU_RS13525		NAD(P)H-dependent oxidoreductase	0.41	PFLU_RS02410		multidrug efflux SMR transporter	low	> 109
Pantoea sp. MT58	0.51	IAI47_20545		NAD(P)H-dependent oxidoreductase	0.26	IAI47_08635		multidrug/spermidine efflux SMR transporter subunit MdtI	low	> 76
Pseudomonas simiae WCS417	0.50	PS417_12845		NAD(P)H dehydrogenase	0.42	PS417_02335		multidrug DMT transporter	low	> 88
Pseudomonas syringae pv. syringae B728a	0.48	Psyr_0122		NAD(P)H dehydrogenase (quinone)	0.46	Psyr_0541		Small multidrug resistance protein	low	> 86
Pseudomonas syringae pv. syringae B728a ΔmexB	0.48	Psyr_0122		NAD(P)H dehydrogenase (quinone)	0.46	Psyr_0541		Small multidrug resistance protein	low	> 86
Enterobacter asburiae PDN3	0.39	EX28DRAFT_1395		Putative NADPH-quinone reductase (modulator of drug activity B)	0.30	EX28DRAFT_1508		Membrane transporters of cations and cationic drugs	low	> 76
Sinorhizobium meliloti 1021	0.21	SMc00379		oxidoreductase	0.49	SMc01523		methyl viologen/ethidium resistance transmembrane protein	low	> 103
Acidovorax sp. GW101-3H11	0.20	Ac3H11_4280		NAD(P)H dehydrogenase, quinone family	0.55	Ac3H11_2948		Ethidium bromide-methyl viologen resistance protein EmrE	0.25	64
Paraburkholderia graminis OAS925	0.19	ABIE53_005186		NAD(P)H dehydrogenase (quinone)	0.48	ABIE53_001959		small multidrug resistance pump	low	> 113
Rhizobium sp. OAE497	0.18	ABIE40_RS01210		NAD(P)H-dependent oxidoreductase	0.47	ABIE40_RS14355		SMR family transporter	low	> 107
Serratia liquefaciens MT49	0.16	IAI46_12660		NAD(P)H-dependent oxidoreductase	0.51	IAI46_13370		QacE family quaternary ammonium compound efflux SMR transporter	—	—

Not shown: 4 genomes with orthologs for HER17_RS16865 only; 42 genomes with orthologs for HER17_RS07420 only