Conservation of cofitness between GFF5010 and GFF4076 in Sphingobium sp. HT1-2

22 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Sphingobium sp. HT1-2	1.0	GFF5010		Protein formerly called heavy metal resistance transcriptional regulator HmrR	1.0	GFF4076		Two-component transcriptional response regulator, LuxR family	0.66	16
Pseudomonas sp. S08-1	0.58	OH686_07400		Cu(I)-responsive transcriptional regulator	0.46	OH686_00055		Two-component system response regulator QseB	low	> 80
Pseudomonas simiae WCS417	0.57	PS417_03155		transcriptional regulator	0.46	PS417_10270		transcriptional regulator	low	> 88
Pseudomonas sp. RS175	0.57	PFR28_05243		HTH-type transcriptional regulator HmrR	0.46	PFR28_02847		Transcriptional regulatory protein QseB	low	> 88
Bosea sp. OAE506	0.57	ABIE41_RS15580		Cu(I)-responsive transcriptional regulator	0.71	ABIE41_RS21475		response regulator transcription factor	low	> 77
Pseudomonas fluorescens FW300-N1B4	0.57	Pf1N1B4_1263		Cu(I)-responsive transcriptional regulator	0.46	Pf1N1B4_105		Two-component system response regulator QseB	—	—
Pseudomonas fluorescens FW300-N2C3	0.57	AO356_08070		transcriptional regulator	0.46	AO356_21280		transcriptional regulator	low	> 104
Pseudomonas fluorescens FW300-N2E3	0.57	AO353_06160		transcriptional regulator	0.47	AO353_19775		transcriptional regulator	low	> 101
Pseudomonas fluorescens FW300-N2E2	0.57	Pf6N2E2_3488		Cu(I)-responsive transcriptional regulator	0.46	Pf6N2E2_41		Two-component system response regulator QseB	low	> 103
Pseudomonas sp. DMC3	0.56	GFF3355		HTH-type transcriptional regulator HmrR	0.47	GFF1365		Transcriptional regulatory protein QseB	low	> 89
Pseudomonas fluorescens SBW25	0.56	PFLU_RS03235		Cu(I)-responsive transcriptional regulator	0.46	PFLU_RS10435		response regulator transcription factor	low	> 109
Pseudomonas fluorescens GW456-L13	0.56	PfGW456L13_25		Cu(I)-responsive transcriptional regulator	0.47	PfGW456L13_2451		Two-component system response regulator QseB	low	> 87
Pseudomonas fluorescens SBW25-INTG	0.56	PFLU_RS03235		Cu(I)-responsive transcriptional regulator	0.46	PFLU_RS10435		response regulator transcription factor	low	> 109
Pseudomonas sp. SVBP6	0.55	COO64_RS26335	cueR	Cu(I)-responsive transcriptional regulator	0.47	COO64_RS17260		response regulator transcription factor	low	> 93
Pseudomonas putida KT2440	0.55	PP_0585		putative metal-sensitive transcriptional regulator, MerR family	0.46	PP_2347		DNA-binding response regulator	low	> 96
Pseudomonas sp. BP01	0.55	JOY50_RS23260	cueR	Cu(I)-responsive transcriptional regulator	0.46	JOY50_RS10885		response regulator transcription factor	low	> 84
Dechlorosoma suillum PS	0.54	Dsui_1064		Cu(I)-responsive transcriptional regulator	0.42	Dsui_2248		response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	low	> 51
Pseudomonas stutzeri RCH2	0.54	Psest_0737		Cu(I)-responsive transcriptional regulator	0.47	Psest_3533		Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	low	> 67
Azospirillum sp. SherDot2	0.54	MPMX19_04396		HTH-type transcriptional regulator HmrR	0.71	MPMX19_04078		Virulence transcriptional regulatory protein PhoP	low	> 112
Erwinia tracheiphila SCR3	0.40	LU632_RS15290	cueR	Cu(I)-responsive transcriptional regulator	0.42	LU632_RS21175	pmrA	two-component system response regulator PmrA	low	> 74
Erwinia tracheiphila HP pepo 2.2	0.39	IJEDHG_01065	cueR	Cu(I)-responsive transcriptional regulator	0.42	IJEDHG_13855	pmrA	two-component system response regulator PmrA	low	> 61
Shewanella oneidensis MR-1	0.37	SO1687		transcriptional regulator, MerR family (NCBI ptt file)	0.54	SO4647		DNA-binding response regulator (NCBI ptt file)	low	> 76
Shewanella sp. ANA-3	0.35	Shewana3_2762		MerR family transcriptional regulator (RefSeq)	0.53	Shewana3_4025		two component transcriptional regulator (RefSeq)	—	—

Not shown: 10 genomes with orthologs for GFF5010 only; 62 genomes with orthologs for GFF4076 only