Conservation of cofitness between CSW01_12320 and CSW01_05935 in Vibrio cholerae E7946 ATCC 55056

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12320 3',5'-cyclic-AMP phosphodiesterase 1.0 CSW01_05935 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.82 16
Dickeya dadantii 3937 0.54 DDA3937_RS01755 3',5'-cyclic-AMP phosphodiesterase 0.59 DDA3937_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Pantoea sp. MT58 0.53 IAI47_03150 3',5'-cyclic-AMP phosphodiesterase 0.58 IAI47_09175 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 76
Erwinia amylovora T8 0.53 OLJFJH_07690 3' 5'-cyclic-AMP phosphodiesterase 0.57 OLJFJH_13480 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 58
Dickeya dianthicola 67-19 0.53 HGI48_RS01650 3',5'-cyclic-AMP phosphodiesterase 0.58 HGI48_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 71
Dickeya dianthicola ME23 0.53 DZA65_RS01725 3',5'-cyclic-AMP phosphodiesterase 0.58 DZA65_RS10950 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 75
Pantoea agglomerans CFBP13505 P0401 0.53 PagCFBP13505_RS11970 3',5'-cyclic-AMP phosphodiesterase 0.58 PagCFBP13505_RS07010 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Rahnella sp. WP5 0.53 EX31_RS25975 3',5'-cyclic-AMP phosphodiesterase 0.58 EX31_RS09970 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.55 67
Klebsiella michiganensis M5al 0.52 BWI76_RS24385 phosphodiesterase 0.58 BWI76_RS11850 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase low > 92
Serratia liquefaciens MT49 0.51 IAI46_21930 3',5'-cyclic-AMP phosphodiesterase 0.60 IAI46_14035 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 86
Erwinia tracheiphila HP pepo 2.2 0.51 IJEDHG_14450 cpdA 3' 5'-cyclic-AMP phosphodiesterase 0.58 IJEDHG_23495 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 61
Erwinia tracheiphila SCR3 0.51 LU632_RS20620 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.58 LU632_RS12765 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Escherichia fergusonii Becca 0.50 EFB2_00776 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA 0.58 EFB2_02664 Tryptophan biosynthesis protein TrpCF low > 86
Escherichia coli Nissle 1917 0.50 ECOLIN_RS17500 3',5'-cyclic-AMP phosphodiesterase 0.58 ECOLIN_RS07605 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 55
Escherichia coli ECRC98 0.50 JDDGAC_22455 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.57 JDDGAC_05210 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 87
Escherichia coli ECRC99 0.50 KEDOAH_09325 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.57 KEDOAH_26085 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_00671 '3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA' transl_table=11 0.58 OHPLBJKB_02421 Tryptophan biosynthesis protein TrpCF low > 74
Escherichia coli ECOR38 0.50 HEPCGN_17695 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.58 HEPCGN_25525 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 88
Escherichia coli ECRC102 0.50 NIAGMN_16585 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.57 NIAGMN_26835 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 80
Escherichia coli ECRC101 0.50 MCAODC_09335 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.57 MCAODC_15600 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 88
Escherichia coli ECOR27 0.50 NOLOHH_10625 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.58 NOLOHH_20325 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD low > 76
Escherichia coli BW25113 0.50 b3032 cpdA cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) 0.58 b1262 trpC N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) low > 76
Escherichia coli ECRC62 0.50 BNILDI_00890 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.58 BNILDI_18470 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD low > 75
Escherichia coli ECRC100 0.50 OKFHMN_18820 cpdA 3',5'-cyclic-AMP phosphodiesterase 0.57 OKFHMN_02665 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 79
Escherichia coli BL21 0.49 ECD_02904 3',5' cAMP phosphodiesterase 0.58 ECD_01236 indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.49 GFF3146 '3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)' transl_table=11 0.59 GFF2724 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24) low > 78
Klebsiella pneumoniae MKP103 0.48 KDGMDA_05210 3' 5'-cyclic-AMP phosphodiesterase 0.57 KDGMDA_19555 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 95
Pectobacterium carotovorum WPP14 0.48 HER17_RS19810 3',5'-cyclic-AMP phosphodiesterase 0.57 HER17_RS10930 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 75
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3070 Predicted phosphohydrolases 0.57 EX28DRAFT_0934 indole-3-glycerol phosphate synthase (EC 4.1.1.48) low > 76
Enterobacter sp. TBS_079 0.48 MPMX20_03879 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA 0.58 MPMX20_02512 Tryptophan biosynthesis protein TrpCF 0.27 62
Shewanella sp. ANA-3 0.44 Shewana3_0728 calcineurin phosphoesterase C-terminal domain-containing protein (RefSeq) 0.43 Shewana3_1517 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.63 39
Shewanella oneidensis MR-1 0.44 SO3901 icc lacZ expression regulator (NCBI ptt file) 0.41 SO3022 trpC/F indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.43 Sama_3045 lacZ expression regulator (RefSeq) 0.50 Sama_2132 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) low > 62
Shewanella loihica PV-4 0.41 Shew_0547 calcineurin phosphoesterase C-terminal domain-containing protein (RefSeq) 0.49 Shew_2254 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq)
Kangiella aquimarina DSM 16071 0.31 B158DRAFT_0977 Predicted phosphohydrolases 0.36 B158DRAFT_2428 indole-3-glycerol phosphate synthase (EC 4.1.1.48) low > 40
Alteromonas macleodii MIT1002 0.21 MIT1002_00673 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA 0.52 MIT1002_01427 Tryptophan biosynthesis protein TrpCF low > 70

Not shown: 33 genomes with orthologs for CSW01_12320 only; 0 genomes with orthologs for CSW01_05935 only