| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_08765 | | TetR/AcrR family transcriptional regulator | 1.0 | CSW01_00595 | | heme biosynthesis protein HemY | 0.68 | 4 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.26 | Psyr_3324 | | transcriptional regulator, TetR family | 0.14 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.26 | Psyr_3324 | | transcriptional regulator, TetR family | 0.14 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | low | > 86 |
| Pseudomonas sp. RS175 | 0.25 | PFR28_03298 | | Nucleoid occlusion factor SlmA | 0.14 | PFR28_04363 | | Protein HemY | low | > 88 |
| Paraburkholderia sabiae LMG 24235 | 0.25 | QEN71_RS09875 | | TetR/AcrR family transcriptional regulator | 0.08 | QEN71_RS24940 | | heme biosynthesis protein HemY | low | > 153 |
| Pseudomonas fluorescens FW300-N1B4 | 0.25 | Pf1N1B4_3415 | | Transcriptional regulator, TetR family | 0.13 | Pf1N1B4_2188 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | — | — |
| Pseudomonas orientalis W4I3 | 0.24 | QF045_RS23950 | | TetR/AcrR family transcriptional regulator | 0.15 | QF045_RS01875 | | heme biosynthesis protein HemY | low | > 93 |
| Pseudomonas fluorescens GW456-L13 | 0.24 | PfGW456L13_1949 | | Transcriptional regulator, TetR family | 0.14 | PfGW456L13_859 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | low | > 87 |
| Shewanella loihica PV-4 | 0.24 | Shew_0299 | | TetR family transcriptional regulator (RefSeq) | 0.12 | Shew_0315 | | HemY domain-containing protein (RefSeq) | low | > 60 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.24 | H281DRAFT_01360 | | transcriptional regulator, TetR family | 0.08 | H281DRAFT_00200 | | HemY protein | — | — |
| Pseudomonas fluorescens SBW25 | 0.24 | PFLU_RS23430 | | TetR/AcrR family transcriptional regulator | 0.15 | PFLU_RS29195 | | heme biosynthesis protein HemY | 0.54 | 16 |
| Pseudomonas fluorescens SBW25-INTG | 0.24 | PFLU_RS23430 | | TetR/AcrR family transcriptional regulator | 0.15 | PFLU_RS29195 | | heme biosynthesis protein HemY | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.23 | GEMAOFIL_04508 | | HTH-type transcriptional regulator RutR | 0.16 | GEMAOFIL_05641 | | Protein HemY | 0.64 | 62 |
| Shewanella sp. ANA-3 | 0.23 | Shewana3_0292 | | TetR family transcriptional regulator (RefSeq) | 0.11 | Shewana3_0383 | | HemY domain-containing protein (RefSeq) | low | > 73 |
| Pseudomonas simiae WCS417 | 0.23 | PS417_21830 | | TetR family transcriptional regulator | 0.15 | PS417_27515 | | heme biosynthesis protein HemY | low | > 88 |
| Paraburkholderia graminis OAS925 | 0.23 | ABIE53_004009 | | TetR/AcrR family transcriptional regulator of autoinduction and epiphytic fitness | 0.08 | ABIE53_001317 | | HemY protein | low | > 113 |
| Pseudomonas sp. DMC3 | 0.23 | GFF4900 | | HTH-type transcriptional regulator RutR | 0.15 | GFF355 | | Protein HemY | low | > 89 |
| Pseudomonas fluorescens FW300-N2E3 | 0.22 | AO353_03115 | | TetR family transcriptional regulator | 0.15 | AO353_08975 | | heme biosynthesis protein HemY | low | > 101 |
| Burkholderia phytofirmans PsJN | 0.22 | BPHYT_RS09345 | | TetR family transcriptional regulator | 0.08 | BPHYT_RS05240 | | heme biosynthesis protein HemY | — | — |
| Shewanella amazonensis SB2B | 0.20 | Sama_0792 | | TetR family transcriptional regulator (RefSeq) | 0.12 | Sama_3257 | | HemY protein (RefSeq) | low | > 62 |
| Dickeya dianthicola 67-19 | 0.15 | HGI48_RS04175 | | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | 0.24 | HGI48_RS20090 | | protoheme IX biogenesis protein HemY | low | > 71 |
Not shown: 5 genomes with orthologs for CSW01_08765 only; 45 genomes with orthologs for CSW01_00595 only