Conservation of cofitness between BWI76_RS19845 and BWI76_RS19805 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS19845 phosphatase 1.0 BWI76_RS19805 Bcr/CflA family multidrug efflux MFS transporter 0.44 19
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF3747 FIG001881: hydrolase of alkaline phosphatase superfamily 0.84 GFF3754 MFS family multidrug transport protein, bicyclomycin resistance protein low > 78
Escherichia coli Nissle 1917 0.83 ECOLIN_RS12785 LPS biosynthesis-modulating metalloenzyme YejM 0.84 ECOLIN_RS12755 multidrug efflux MFS transporter Bcr — —
Escherichia coli BL21 0.83 ECD_02118 essential inner membrane DUF3413 domain-containing protein; lipid A production and membrane permeability factor 0.82 ECD_02112 bicyclomycin/cysteine/sulfonamide efflux transporter low > 61
Escherichia coli ECRC99 0.83 KEDOAH_04850 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.84 KEDOAH_04820 bcr multidrug efflux MFS transporter Bcr — —
Escherichia fergusonii Becca 0.83 EFB2_01668 Inner membrane protein YejM 0.84 EFB2_01674 Bicyclomycin resistance protein low > 86
Escherichia coli ECRC102 0.83 NIAGMN_21100 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.84 NIAGMN_21130 bcr multidrug efflux MFS transporter Bcr — —
Escherichia coli ECRC98 0.83 JDDGAC_27295 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.84 JDDGAC_27325 bcr multidrug efflux MFS transporter Bcr low > 86
Escherichia coli ECOR38 0.83 HEPCGN_22600 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.84 HEPCGN_22630 bcr multidrug efflux MFS transporter Bcr low > 87
Escherichia coli ECRC100 0.83 OKFHMN_23335 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.83 OKFHMN_23365 bcr multidrug efflux MFS transporter Bcr low > 80
Enterobacter asburiae PDN3 0.83 EX28DRAFT_0373 Predicted hydrolase of alkaline phosphatase superfamily 0.86 EX28DRAFT_0379 drug resistance transporter, Bcr/CflA subfamily low > 76
Escherichia coli ECRC101 0.83 MCAODC_14385 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.84 MCAODC_14415 bcr multidrug efflux MFS transporter Bcr low > 87
Escherichia coli BW25113 0.83 b2188 yejM predicted hydrolase, inner membrane (NCBI) 0.82 b2182 bcr bicyclomycin/multidrug efflux system (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01521 Inner membrane protein YejM 0.82 OHPLBJKB_01527 Bicyclomycin resistance protein low > 73
Escherichia coli ECOR27 0.83 NOLOHH_14910 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 NOLOHH_14940 bcr multidrug efflux MFS transporter Bcr low > 75
Escherichia coli ECRC62 0.83 BNILDI_13830 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 BNILDI_13860 bcr multidrug efflux MFS transporter Bcr low > 75
Enterobacter sp. TBS_079 0.82 MPMX20_03154 Inner membrane protein YejM 0.85 MPMX20_03148 Bicyclomycin resistance protein low > 85
Erwinia tracheiphila SCR3 0.66 LU632_RS17620 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.61 LU632_RS17590 Bcr/CflA family multidrug efflux MFS transporter — —
Pantoea sp. MT58 0.66 IAI47_06560 DUF3413 domain-containing protein 0.71 IAI47_06590 Bcr/CflA family multidrug efflux MFS transporter low > 76
Rahnella sp. WP5 0.63 EX31_RS19220 DUF3413 domain-containing protein 0.67 EX31_RS19190 Bcr/CflA family multidrug efflux MFS transporter low > 89
Serratia liquefaciens MT49 0.63 IAI46_17370 DUF3413 domain-containing protein 0.73 IAI46_17340 Bcr/CflA family multidrug efflux MFS transporter low > 86
Dickeya dadantii 3937 0.62 DDA3937_RS09115 DUF3413 domain-containing protein 0.71 DDA3937_RS09165 Bcr/CflA family multidrug efflux MFS transporter low > 74
Dickeya dianthicola 67-19 0.62 HGI48_RS09155 DUF3413 domain-containing protein 0.70 HGI48_RS09205 Bcr/CflA family multidrug efflux MFS transporter low > 71
Dickeya dianthicola ME23 0.61 DZA65_RS09455 DUF3413 domain-containing protein 0.70 DZA65_RS09505 Bcr/CflA family multidrug efflux MFS transporter low > 75
Pectobacterium carotovorum WPP14 0.61 HER17_RS12985 LPS biosynthesis-modulating metalloenzyme YejM 0.73 HER17_RS12945 Bcr/CflA family multidrug efflux MFS transporter low > 75
Vibrio cholerae E7946 ATCC 55056 0.38 CSW01_10200 DUF3413 domain-containing protein 0.44 CSW01_08215 Bcr/CflA family drug resistance efflux transporter low > 62
Shewanella sp. ANA-3 0.24 Shewana3_2428 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (RefSeq) 0.23 Shewana3_2268 Bcr/CflA subfamily drug resistance transporter (RefSeq) low > 73
Shewanella oneidensis MR-1 0.24 SO2175 conserved hypothetical protein (NCBI ptt file) 0.23 SO2280 bicyclomycin resistance protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.22 Shew_1470 sulfatase (RefSeq) 0.24 Shew_1777 Bcr/CflA subfamily drug resistance transporter (RefSeq) — —
Shewanella amazonensis SB2B 0.19 Sama_1555 hypothetical protein (RefSeq) 0.24 Sama_2017 bicyclomycin resistance protein (RefSeq) low > 62
Lysobacter sp. OAE881 0.12 ABIE51_RS08280 sulfatase-like hydrolase/transferase 0.19 ABIE51_RS14645 multidrug effflux MFS transporter low > 62

Not shown: 0 genomes with orthologs for BWI76_RS19845 only; 40 genomes with orthologs for BWI76_RS19805 only