Conservation of cofitness between BWI76_RS11275 and BWI76_RS01165 in Klebsiella michiganensis M5al

36 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS11275 sensor protein PhoQ 1.0 BWI76_RS01165 protoheme IX biogenesis protein HemY 0.37 12
Enterobacter asburiae PDN3 0.83 EX28DRAFT_1801 Signal transduction histidine kinase 0.86 EX28DRAFT_4471 heme biosynthesis-associated TPR protein low > 76
Escherichia coli BL21 0.83 ECD_01127 sensory histidine kinase in two-component regulatory system with PhoP 0.90 ECD_03677 putative protoheme IX synthesis protein — —
Escherichia coli ECRC62 0.82 BNILDI_19085 phoQ two-component system sensor histidine kinase PhoQ 0.90 BNILDI_04925 hemY protoheme IX biogenesis protein HemY low > 75
Escherichia coli BW25113 0.82 b1129 phoQ sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) 0.90 b3802 hemY predicted protoheme IX synthesis protein (NCBI) low > 76
Escherichia coli ECOR38 0.82 HEPCGN_24195 phoQ two-component system sensor histidine kinase PhoQ 0.90 HEPCGN_13185 hemY protoheme IX biogenesis protein HemY low > 87
Escherichia coli ECOR27 0.82 NOLOHH_20920 phoQ two-component system sensor histidine kinase PhoQ 0.90 NOLOHH_06610 hemY protoheme IX biogenesis protein HemY low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.82 OHPLBJKB_02539 Sensor protein PhoQ 0.90 OHPLBJKB_04251 Protein HemY low > 73
Escherichia fergusonii Becca 0.82 EFB2_02846 Sensor protein PhoQ 0.90 EFB2_04836 Protein HemY low > 86
Escherichia coli ECRC100 0.82 OKFHMN_00725 phoQ two-component system sensor histidine kinase PhoQ 0.90 OKFHMN_14465 hemY protoheme IX biogenesis protein HemY low > 80
Escherichia coli ECRC102 0.82 NIAGMN_24870 phoQ two-component system sensor histidine kinase PhoQ 0.90 NIAGMN_12220 hemY protoheme IX biogenesis protein HemY — —
Escherichia coli ECRC101 0.82 MCAODC_22360 phoQ two-component system sensor histidine kinase PhoQ 0.90 MCAODC_04970 hemY protoheme IX biogenesis protein HemY 0.53 30
Escherichia coli Nissle 1917 0.82 ECOLIN_RS06605 two-component system sensor histidine kinase PhoQ 0.90 ECOLIN_RS21820 protoheme IX biogenesis protein HemY low > 55
Escherichia coli ECRC99 0.82 KEDOAH_24810 phoQ two-component system sensor histidine kinase PhoQ 0.90 KEDOAH_13685 hemY protoheme IX biogenesis protein HemY — —
Escherichia coli ECRC98 0.82 JDDGAC_06640 phoQ two-component system sensor histidine kinase PhoQ 0.90 JDDGAC_18090 hemY protoheme IX biogenesis protein HemY low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.82 GFF3414 Sensor protein PhoQ (EC 2.7.13.3) 0.85 GFF226 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) low > 78
Enterobacter sp. TBS_079 0.81 MPMX20_01810 Virulence sensor histidine kinase PhoQ 0.85 MPMX20_04473 Protein HemY low > 85
Rahnella sp. WP5 0.59 EX31_RS24555 two-component system sensor histidine kinase PhoQ 0.71 EX31_RS15130 protoheme IX biogenesis protein HemY low > 89
Erwinia tracheiphila SCR3 0.59 LU632_RS14595 phoQ two-component system sensor histidine kinase PhoQ 0.74 LU632_RS24175 hemY protoheme IX biogenesis protein HemY low > 74
Dickeya dadantii 3937 0.58 DDA3937_RS11505 two-component system sensor histidine kinase PhoQ 0.66 DDA3937_RS19935 protoheme IX biogenesis protein HemY low > 74
Pantoea sp. MT58 0.58 IAI47_11935 two-component system sensor histidine kinase PhoQ 0.70 IAI47_18440 protoheme IX biogenesis protein HemY low > 76
Serratia liquefaciens MT49 0.58 IAI46_10390 two-component system sensor histidine kinase PhoQ 0.68 IAI46_00680 protoheme IX biogenesis protein HemY low > 86
Dickeya dianthicola 67-19 0.58 HGI48_RS11550 two-component system sensor histidine kinase PhoQ 0.65 HGI48_RS20090 protoheme IX biogenesis protein HemY low > 71
Pectobacterium carotovorum WPP14 0.57 HER17_RS11645 two-component system sensor histidine kinase PhoQ 0.69 HER17_RS01300 protoheme IX biogenesis protein HemY low > 75
Dickeya dianthicola ME23 0.57 DZA65_RS11885 two-component system sensor histidine kinase PhoQ 0.65 DZA65_RS21135 protoheme IX biogenesis protein HemY low > 75
Pseudomonas sp. RS175 0.23 PFR28_03243 Virulence sensor histidine kinase PhoQ 0.12 PFR28_04363 Protein HemY low > 88
Pseudomonas fluorescens FW300-N2E3 0.22 AO353_02810 histidine kinase 0.12 AO353_08975 heme biosynthesis protein HemY low > 101
Pseudomonas fluorescens FW300-N2C3 0.22 AO356_18970 histidine kinase 0.14 AO356_12800 heme biosynthesis protein HemY low > 104
Pseudomonas fluorescens FW300-N2E2 0.22 Pf6N2E2_5705 Sensor protein PhoQ (EC 2.7.13.3) 0.14 Pf6N2E2_4433 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) low > 103
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_3484 Sensor protein PhoQ (EC 2.7.13.3) 0.11 Pf1N1B4_2188 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) — —
Pseudomonas fluorescens GW456-L13 0.21 PfGW456L13_2012 Sensor protein PhoQ (EC 2.7.13.3) 0.12 PfGW456L13_859 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) low > 87
Pseudomonas stutzeri RCH2 0.21 Psest_3884 Signal transduction histidine kinase 0.17 Psest_3745 Uncharacterized enzyme of heme biosynthesis low > 67
Pseudomonas putida KT2440 0.20 PP_1187 sensor protein 0.12 PP_0189 putative heme biosynthesis protein low > 96
Kangiella aquimarina DSM 16071 0.20 B158DRAFT_1561 Signal transduction histidine kinase 0.17 B158DRAFT_0255 Uncharacterized enzyme of heme biosynthesis low > 40
Pseudomonas fluorescens SBW25-INTG 0.18 PFLU_RS23125 HAMP domain-containing protein 0.12 PFLU_RS29195 heme biosynthesis protein HemY low > 109
Pseudomonas fluorescens SBW25 0.18 PFLU_RS23125 HAMP domain-containing protein 0.12 PFLU_RS29195 heme biosynthesis protein HemY low > 109
Pseudomonas simiae WCS417 0.18 PS417_21510 histidine kinase 0.12 PS417_27515 heme biosynthesis protein HemY low > 88

Not shown: 1 genomes with orthologs for BWI76_RS11275 only; 9 genomes with orthologs for BWI76_RS01165 only