Conservation of cofitness between BWI76_RS02510 and BWI76_RS00985 in Klebsiella michiganensis M5al

33 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS02510 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 1.0 BWI76_RS00985 transcriptional regulator IlvY 0.26 3
Enterobacter asburiae PDN3 0.80 EX28DRAFT_3364 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.92 EX28DRAFT_4445 Transcriptional regulator low > 76
Escherichia coli Nissle 1917 0.79 ECOLIN_RS24205 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 ECOLIN_RS21675 HTH-type transcriptional activator IlvY low > 55
Enterobacter sp. TBS_079 0.79 MPMX20_00448 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.92 MPMX20_04497 HTH-type transcriptional regulator GltC low > 85
Escherichia coli BW25113 0.79 b4167 yjeF predicted carbohydrate kinase (NCBI) 0.93 b3773 ilvY DNA-binding transcriptional dual regulator (NCBI) low > 76
Escherichia coli BL21 0.79 ECD_04034 bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase 0.93 ECD_03651 transcriptional activator of ilvC; autorepressor low > 61
Escherichia coli ECRC102 0.78 NIAGMN_10130 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 NIAGMN_12385 ilvY HTH-type transcriptional activator IlvY — —
Escherichia coli ECRC100 0.78 OKFHMN_12280 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 OKFHMN_14630 ilvY HTH-type transcriptional activator IlvY low > 80
Escherichia coli ECRC99 0.78 KEDOAH_15875 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 KEDOAH_13520 ilvY HTH-type transcriptional activator IlvY — —
Escherichia coli ECRC98 0.78 JDDGAC_15920 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 JDDGAC_18250 ilvY HTH-type transcriptional activator IlvY low > 86
Escherichia coli ECRC101 0.78 MCAODC_02795 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 MCAODC_05135 ilvY HTH-type transcriptional activator IlvY low > 87
Escherichia fergusonii Becca 0.78 EFB2_04368 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.92 EFB2_04863 HTH-type transcriptional regulator HdfR low > 86
Escherichia coli ECOR27 0.78 NOLOHH_04545 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 NOLOHH_06765 ilvY HTH-type transcriptional activator IlvY low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.78 OHPLBJKB_03875 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.93 OHPLBJKB_04280 HTH-type transcriptional regulator GltC low > 73
Escherichia coli ECRC62 0.78 BNILDI_06945 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 BNILDI_04760 ilvY HTH-type transcriptional activator IlvY low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF820 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.92 GFF2897 HTH-type transcriptional regulator IlvY low > 78
Escherichia coli ECOR38 0.78 HEPCGN_10510 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.92 HEPCGN_13340 ilvY HTH-type transcriptional activator IlvY low > 87
Erwinia tracheiphila SCR3 0.67 LU632_RS02030 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.77 LU632_RS24390 ilvY HTH-type transcriptional activator IlvY low > 74
Rahnella sp. WP5 0.65 EX31_RS08845 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.74 EX31_RS15015 HTH-type transcriptional activator IlvY low > 89
Pantoea sp. MT58 0.64 IAI47_02565 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.72 IAI47_01045 HTH-type transcriptional activator IlvY low > 76
Dickeya dianthicola 67-19 0.64 HGI48_RS18570 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.67 HGI48_RS20275 HTH-type transcriptional activator IlvY low > 71
Dickeya dianthicola ME23 0.63 DZA65_RS19705 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.67 DZA65_RS21315 HTH-type transcriptional activator IlvY low > 75
Serratia liquefaciens MT49 0.63 IAI46_01600 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.71 IAI46_24330 HTH-type transcriptional activator IlvY low > 86
Pectobacterium carotovorum WPP14 0.62 HER17_RS02560 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.70 HER17_RS01095 HTH-type transcriptional activator IlvY low > 75
Dickeya dadantii 3937 0.60 DDA3937_RS18635 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.67 DDA3937_RS20135 HTH-type transcriptional activator IlvY low > 74
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_14940 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.45 CSW01_00835 HTH-type transcriptional activator IlvY low > 62
Alteromonas macleodii MIT1002 0.38 MIT1002_03793 Nicotinamide nucleotide repair protein 0.41 MIT1002_04044 HTH-type transcriptional regulator GltC low > 70
Shewanella amazonensis SB2B 0.36 Sama_3030 YjeF protein (RefSeq) 0.48 Sama_3283 DNA-binding transcriptional regulator IlvY (RefSeq) low > 62
Shewanella sp. ANA-3 0.36 Shewana3_0592 carbohydrate kinase, YjeF related protein (RefSeq) 0.53 Shewana3_0354 DNA-binding transcriptional regulator IlvY (RefSeq) low > 73
Shewanella oneidensis MR-1 0.36 SO0598 yjeF yjeF protein (NCBI ptt file) 0.53 SO4350 ilvY transcriptional regulator ilvY (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.34 Shew_0561 carbohydrate kinase, YjeF-related protein (RefSeq) 0.51 Shew_0287 DNA-binding transcriptional regulator IlvY (RefSeq) low > 60
Pseudomonas stutzeri RCH2 0.31 Psest_0678 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.16 Psest_2671 Transcriptional regulator low > 67
Pseudomonas sp. S08-1 0.28 OH686_09495 NAD(P)H-hydrate epimerase / ADP-dependent (S)-NAD(P)H-hydrate dehydratase 0.40 OH686_08120 Transcriptional regulator IlvY, LysR family low > 80
Variovorax sp. SCN45 0.17 GFF397 NAD(P)H-hydrate epimerase (EC 5.1.99.6) / ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) 0.17 GFF1571 Transcriptional regulator, LysR family low > 127

Not shown: 61 genomes with orthologs for BWI76_RS02510 only; 0 genomes with orthologs for BWI76_RS00985 only