Conservation of cofitness between A4249_RS13190 and A4249_RS10720 in Brevundimonas sp. GW460-12-10-14-LB2

31 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS13190 2-oxo acid dehydrogenase subunit E2 1.0 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.92 11
Shewanella sp. ANA-3 0.30 Shewana3_2129 dihydrolipoamide acetyltransferase (RefSeq) 0.44 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.29 Sama_1711 dihydrolipoamide acetyltransferase (RefSeq) 0.41 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.29 SO2341 alpha keto acid dehydrogenase complex, E2 component (NCBI ptt file) 0.45 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.28 Shew_1927 dihydrolipoamide acetyltransferase (RefSeq) 0.44 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.23 MIT1002_02014 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 0.47 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase low > 70
Klebsiella michiganensis M5al 0.20 BWI76_RS04885 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.47 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase — —
Rahnella sp. WP5 0.19 EX31_RS03475 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.41 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Pantoea sp. MT58 0.19 IAI47_15805 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.47 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia fergusonii Becca 0.19 EFB2_03930 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 0.43 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE — —
Pectobacterium carotovorum WPP14 0.19 HER17_RS03295 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.41 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC100 0.18 OKFHMN_10495 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.44 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC101 0.18 MCAODC_01010 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.44 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC99 0.18 KEDOAH_17660 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.44 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli BL21 0.18 ECD_00114 pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2 0.47 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase — —
Erwinia tracheiphila SCR3 0.18 LU632_RS03085 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.41 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.18 OHPLBJKB_03546 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 0.48 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE — —
Escherichia coli BW25113 0.18 b0115 aceF dihydrolipoamide acetyltransferase (NCBI) 0.47 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) — —
Escherichia coli ECRC102 0.18 NIAGMN_08345 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.44 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC62 0.18 BNILDI_08770 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.47 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 75
Escherichia coli ECRC98 0.18 JDDGAC_14090 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.44 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECOR27 0.18 NOLOHH_02840 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.45 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECOR38 0.18 HEPCGN_08475 aceF pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.47 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 87
Xanthomonas campestris pv. campestris strain 8004 0.18 Xcc-8004.4587.1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) 0.48 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) — —
Enterobacter asburiae PDN3 0.18 EX28DRAFT_3711 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form 0.47 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.18 GFF121 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) 0.45 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 78
Dickeya dianthicola ME23 0.18 DZA65_RS18995 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.45 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Vibrio cholerae E7946 ATCC 55056 0.18 CSW01_12215 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.46 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase — —
Dickeya dianthicola 67-19 0.17 HGI48_RS17845 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.45 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Dickeya dadantii 3937 0.17 DDA3937_RS17920 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase 0.45 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Dyella japonica UNC79MFTsu3.2 0.17 ABZR86_RS12285 dihydrolipoyllysine-residue acetyltransferase 0.46 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Enterobacter sp. TBS_079 0.17 MPMX20_00808 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 0.48 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE — —

Not shown: 19 genomes with orthologs for A4249_RS13190 only; 18 genomes with orthologs for A4249_RS10720 only