Conservation of cofitness between b1850 and b1241 in Escherichia coli BW25113

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 1.0 b1241 adhE fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) 0.40 7
Escherichia coli ECRC101 1.00 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 MCAODC_21655 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli ECRC99 1.00 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 KEDOAH_25600 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia fergusonii Becca 1.00 EFB2_02093 KHG/KDPG aldolase 1.00 EFB2_02686 Aldehyde-alcohol dehydrogenase low > 86
Escherichia coli ECRC98 1.00 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 JDDGAC_05970 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli ECRC102 1.00 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NIAGMN_27630 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01879 KHG/KDPG aldolase 1.00 OHPLBJKB_02444 Aldehyde-alcohol dehydrogenase low > 73
Escherichia coli BL21 1.00 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 1.00 ECD_01215 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 ECOLIN_RS07500 bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli ECRC62 1.00 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 BNILDI_18590 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli ECOR38 1.00 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 HEPCGN_25070 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 85
Escherichia coli ECRC101 1.00 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 OKFHMN_28605 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Escherichia coli ECOR27 0.99 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NOLOHH_20445 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.94 GFF2749 Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_0706 Entner-Doudoroff aldolase 0.93 EX28DRAFT_0865 Alcohol dehydrogenase, class IV low > 76
Enterobacter sp. TBS_079 0.96 MPMX20_02755 KHG/KDPG aldolase 0.93 MPMX20_02589 Aldehyde-alcohol dehydrogenase low > 85
Pectobacterium carotovorum WPP14 0.91 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.89 HER17_RS11030 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 75
Dickeya dadantii 3937 0.91 DDA3937_RS10140 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.89 DDA3937_RS10360 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 74
Dickeya dianthicola 67-19 0.91 HGI48_RS10170 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.90 HGI48_RS10370 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 71
Dickeya dianthicola ME23 0.91 DZA65_RS10585 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.90 DZA65_RS10845 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 75
Pantoea sp. MT58 0.89 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.90 IAI47_09055 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.25 76
Rahnella sp. WP5 0.88 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.90 EX31_RS10075 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 89
Serratia liquefaciens MT49 0.88 IAI46_14570 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.90 IAI46_14220 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.34 85
Klebsiella michiganensis M5al 0.87 BWI76_RS18095 ketohydroxyglutarate aldolase 0.93 BWI76_RS17250 bifunctional acetaldehyde-CoA/alcohol dehydrogenase — —
Erwinia tracheiphila SCR3 0.81 LU632_RS13355 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.89 LU632_RS12895 adhE bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 74
Shewanella amazonensis SB2B 0.68 Sama_1809 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.74 Sama_1693 bifunctional acetaldehyde-CoA/alcohol dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.66 SO2486 eda 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI ptt file) 0.76 SO2136 adhE aldehyde-alcohol dehydrogenase (NCBI ptt file) — —
Shewanella loihica PV-4 0.65 Shew_2045 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.73 Shew_1910 bifunctional acetaldehyde-CoA/alcohol dehydrogenase (RefSeq) — —
Shewanella sp. ANA-3 0.65 Shewana3_2148 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.76 Shewana3_1788 bifunctional acetaldehyde-CoA/alcohol dehydrogenase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_01465 ketohydroxyglutarate aldolase 0.78 CSW01_10165 bifunctional acetaldehyde-CoA/alcohol dehydrogenase low > 62
Azospirillum brasilense Sp245 0.39 AZOBR_RS29850 ketohydroxyglutarate aldolase 0.75 AZOBR_RS32240 acetaldehyde dehydrogenase — —

Not shown: 54 genomes with orthologs for b1850 only; 3 genomes with orthologs for b1241 only