| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15945 | | helix-turn-helix domain-containing protein | insig. | 100 | 100 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS11905 | | helix-turn-helix domain-containing protein | insig. | 59 | 99 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02065 | | response regulator receiver domain protein | insig. | 37 | 84 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04371 | | response regulator receiver domain protein | insig. | 35 | 84 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1635 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 34 | 84 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4137 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 34 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3172 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 33 | 81 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS02825 | | response regulator | insig. | 34 | 82 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08595 | | response regulator | insig. | 34 | 82 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2826 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | cofit | 32 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03504 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 32 | 84 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS02790 | | response regulator | insig. | 33 | 82 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS05430 | | response regulator | insig. | 32 | 84 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS05130 | | response regulator | insig. | 31 | 78 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS11775 | | response regulator | sig. | 30 | 78 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS13160 | | response regulator | cofit | 28 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01894 | | transcriptional regulator, AraC family | strong | 23 | 98 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS07185 | | two-component regulator propeller domain-containing protein | insig. | 24 | 87 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS04050 | | helix-turn-helix domain-containing protein | insig. | 22 | 99 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4663 | | two-component system sensor histidine kinase/response (NCBI ptt file) | strong | 23 | 84 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_05479 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 83 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS13495 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 23 | 91 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS00710 | | hypothetical protein | insig. | 24 | 84 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06050 | | hypothetical protein | insig. | 23 | 88 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08545 | | response regulator | insig. | 23 | 84 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS06690 | | response regulator | sig. | 22 | 85 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04483 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 24 | 82 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03607 | | putative flagellar protein FliS | insig. | 22 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02648 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 23 | 84 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2923 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 84 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3754 | | Signal transduction histidine kinase | insig. | 24 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00493 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 85 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08430 | | response regulator | insig. | 22 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02182 | | response regulator receiver domain protein | cofit | 22 | 84 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11130 | | two-component regulator propeller domain-containing protein | cofit | 23 | 85 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4259 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Y_Y_Y domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase./Two component regulator propeller./Bacterial regulatory helix-turn-helix proteins, AraC family. | insig. | 23 | 88 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14215 | | hypothetical protein | insig. | 24 | 84 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 22 | 82 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06780 | | hybrid sensor histidine kinase/response regulator | insig. | 24 | 81 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04394 | | response regulator receiver domain protein | strong | 22 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01840 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 22 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02065 | | response regulator receiver domain protein | insig. | 56 | 13 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS02335 | | response regulator | strong | 29 | 41 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS03465 | | response regulator | sig. | 21 | 94 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS02485 | | hypothetical protein | insig. | 27 | 45 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2760 | | Signal transduction histidine kinase | insig. | 24 | 40 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS02790 | | response regulator | insig. | 45 | 16 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14910 | | helix-turn-helix domain-containing protein | insig. | 22 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3465 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 81 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10630 | | helix-turn-helix domain-containing protein | insig. | 22 | 87 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03437 | | response regulator receiver domain protein | strong | 22 | 77 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS08945 | | helix-turn-helix domain-containing protein | insig. | 25 | 43 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS05430 | | response regulator | insig. | 44 | 15 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS13435 | | helix-turn-helix domain-containing protein | insig. | 25 | 43 |
| | Cellulophaga baltica 18 | M666_RS18760 | | sensor histidine kinase | insig. | 22 | 92 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS13410 | | hypothetical protein | insig. | 21 | 82 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2860 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | insig. | 20 | 82 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03441 | | response regulator receiver domain protein | insig. | 22 | 83 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11200 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 21 | 91 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS15155 | | hybrid sensor histidine kinase/response regulator transcription factor | cofit | 23 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1635 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 43 | 16 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS02825 | | response regulator | insig. | 42 | 16 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08595 | | response regulator | insig. | 41 | 16 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0504 | | Signal transduction histidine kinase | insig. | 22 | 81 |
| | Cellulophaga baltica 18 | M666_RS02185 | | two-component regulator propeller domain-containing protein | insig. | 22 | 80 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3172 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 42 | 16 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03504 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 39 | 19 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS08375 | | two-component regulator propeller domain-containing protein | insig. | 22 | 83 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4137 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 41 | 16 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS00165 | | response regulator | strong | 20 | 83 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19095 | | hybrid sensor histidine kinase/response regulator | insig. | 19 | 80 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS05785 | | hypothetical protein | insig. | 22 | 78 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4346 | | Signal transduction histidine kinase | insig. | 22 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3334 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | strong | 27 | 40 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS03955 | | response regulator | insig. | 21 | 80 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS09500 | | response regulator | insig. | 21 | 80 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04371 | | response regulator receiver domain protein | insig. | 40 | 15 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS12100 | | hybrid sensor histidine kinase/response regulator | strong | 19 | 80 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01996 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | strong | 26 | 40 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS00425 | | helix-turn-helix domain-containing protein | insig. | 24 | 43 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15110 | | response regulator | insig. | 20 | 80 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS12365 | | ATP-binding protein | insig. | 19 | 80 |
| | Cellulophaga baltica 18 | M666_RS00005 | | two-component regulator propeller domain-containing protein | insig. | 24 | 78 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10925 | | response regulator | insig. | 21 | 83 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS11435 | | two-component regulator propeller domain-containing protein | cofit | 26 | 44 |
| | Shewanella sp. ANA-3 | Shewana3_3829 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | cofit | 21 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3660 | | transcriptional regulator (NCBI ptt file) | insig. | 23 | 40 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01673 | | response regulator receiver domain protein | insig. | 22 | 82 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02857 | | conserved hypothetical protein TIGR03982 | insig. | 21 | 83 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS10265 | | hypothetical protein | insig. | 23 | 79 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00239 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 78 |
| | Shewanella oneidensis MR-1 | SO0341 | | sensory box protein (NCBI ptt file) | insig. | 25 | 39 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0958 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | insig. | 20 | 92 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03489 | | transcriptional regulator, AraC family | insig. | 24 | 43 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2897 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 86 |
| | Shewanella amazonensis SB2B | Sama_3298 | | sensory box protein (RefSeq) | insig. | 21 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2826 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | cofit | 45 | 12 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08780 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 25 | 40 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15170 | | response regulator | insig. | 20 | 83 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08780 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 21 | 79 |