Conservation of cofitness between RR42_RS15890 and RR42_RS14790 in Cupriavidus basilensis FW507-4G11

15 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Cupriavidus basilensis FW507-4G11	1.0	RR42_RS15890		heme biosynthesis protein HemY	1.0	RR42_RS14790		cobalamin biosynthesis protein CobD	0.86	2
Ralstonia sp. UNC404CL21Col	0.73	ABZR87_RS16125		heme biosynthesis protein HemY	0.62	ABZR87_RS09625		CobD/CbiB family protein	0.74	1
Ralstonia solanacearum PSI07	0.73	RPSI07_RS13115		heme biosynthesis protein HemY	0.63	RPSI07_RS19540		threonine-phosphate decarboxylase	0.97	2
Ralstonia solanacearum IBSBF1503	0.73	RALBFv3_RS04235		heme biosynthesis protein HemY	0.59	RALBFv3_RS13930		cobalamin biosynthesis protein CobD	0.81	2
Ralstonia solanacearum UW163	0.73	UW163_RS09435		heme biosynthesis protein HemY	0.59	UW163_RS15880		cobalamin biosynthesis protein CobD	—	—
Ralstonia solanacearum GMI1000	0.71	RS_RS11825		heme biosynthesis protein HemY	0.63	RS_RS04665		cobalamin biosynthesis protein CobD	0.86	1
Paraburkholderia bryophila 376MFSha3.1	0.47	H281DRAFT_00200		HemY protein	0.59	H281DRAFT_04297		adenosylcobinamide-phosphate synthase	—	—
Burkholderia phytofirmans PsJN	0.47	BPHYT_RS05240		heme biosynthesis protein HemY	0.59	BPHYT_RS14740		threonine-phosphate decarboxylase	—	—
Paraburkholderia graminis OAS925	0.47	ABIE53_001317		HemY protein	0.60	ABIE53_003123		adenosylcobinamide-phosphate synthase	0.87	1
Paraburkholderia sabiae LMG 24235	0.47	QEN71_RS24940		heme biosynthesis protein HemY	0.56	QEN71_RS04235		CobD/CbiB family protein	0.74	5
Herbaspirillum seropedicae SmR1	0.42	HSERO_RS14650		porphyrin biosynthesis protein	0.46	HSERO_RS07600		threonine-phosphate decarboxylase	—	—
Dechlorosoma suillum PS	0.23	Dsui_1599		putative enzyme of heme biosynthesis	0.36	Dsui_3240		cobalamin biosynthesis protein cobD/CbiB	low	> 51
Acidovorax sp. GW101-3H11	0.14	Ac3H11_3549		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.36	Ac3H11_1681		Similar to cobalamin biosynthesis protein CbiB	0.57	16
Variovorax sp. OAS795	0.13	ABID97_RS08240		heme biosynthesis HemY N-terminal domain-containing protein	0.37	ABID97_RS08765		CobD/CbiB family protein	0.63	1
Hydrogenophaga sp. GW460-11-11-14-LB1	0.09	GFF119		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.30	GFF5735		Adenosylcobinamide-phosphate synthase (EC 6.3.1.10)	0.88	2
Variovorax sp. SCN45	0.07	GFF3842		Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	0.37	GFF3954		Similar to cobalamin biosynthesis protein CbiB	low	> 127

Not shown: 18 genomes with orthologs for RR42_RS15890 only; 3 genomes with orthologs for RR42_RS14790 only